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Q0UWR1

- Q0UWR1_PHANO

UniProt

Q0UWR1 - Q0UWR1_PHANO

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Protein

Histone-lysine N-methyltransferase, H3 lysine-4 specific

Gene

SNOG_03803

Organism
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].UniRule annotationSAAS annotation

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: UniProtKB-EC
  2. nucleic acid binding Source: InterPro
  3. nucleotide binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulatorUniRule annotation, MethyltransferaseUniRule annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferase, H3 lysine-4 specificUniRule annotation (EC:2.1.1.43UniRule annotation)
Gene namesi
ORF Names:SNOG_03803Imported
OrganismiPhaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)Imported
Taxonomic identifieri321614 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesPleosporomycetidaePleosporalesPleosporineaePhaeosphaeriaceaeParastagonospora
ProteomesiUP000001055: Unassembled WGS sequence

Subcellular locationi

Nucleus UniRule annotation

GO - Cellular componenti

  1. chromosome Source: UniProtKB-KW
  2. Set1C/COMPASS complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

ChromosomeUniRule annotation, NucleusUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Component of the COMPASS (Set1C) complex.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ0UWR1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.
Contains SET domain.SAAS annotation
Contains post-SET domain.SAAS annotation

Phylogenomic databases

InParanoidiQ0UWR1.
KOiK11422.
OMAiDKTGYYI.
OrthoDBiEOG7P8PH3.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
InterProiIPR024657. COMPASS_Set1_N-SET.
IPR017111. Hist_H3-K4_MeTrfase_1_fun.
IPR012677. Nucleotide-bd_a/b_plait.
IPR003616. Post-SET_dom.
IPR000504. RRM_dom.
IPR024636. SET_assoc.
IPR001214. SET_dom.
[Graphical view]
PfamiPF11764. N-SET. 1 hit.
PF00076. RRM_1. 1 hit.
PF00856. SET. 1 hit.
PF11767. SET_assoc. 1 hit.
[Graphical view]
PIRSFiPIRSF037104. Histone_H3-K4_mtfrase_Set1_fun. 1 hit.
SMARTiSM00508. PostSET. 1 hit.
SM00360. RRM. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS50868. POST_SET. 1 hit.
PS50102. RRM. 1 hit.
PS51572. SAM_MT43_1. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0UWR1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSRSGQAISL SALTPLTTSS PSPRSAKTSY DTMNGTSSSR AAPSSAPENV
60 70 80 90 100
ANTITPVNTP PETRKSVFPA DGVMAKRILY DPYSDAKLEK KVRHSKPAQY
110 120 130 140 150
KTVLDKGDPS PPPDPRLALA GYTSGSYILK PTAKSKLRIA PYIAKPYAFD
160 170 180 190 200
NRISCGPGPA TQVVVTGFDP LTPDSQLRGF FSTYGDVESL RAEVHPDNGS
210 220 230 240 250
PLGICLIKFR DTPQARGSVA IKASTSAKRA EREGSNQRLG QQVIKVHTDR
260 270 280 290 300
EGRRCAKLVE LVVQKSRKQE ENIRAKAAAK AAKASALATP ATFDLPANVP
310 320 330 340 350
KGPSGRGARP PIPVPREPLN KKAALSHLIE KDPIKPKLKR APYLFIAHQY
360 370 380 390 400
VPVLSTTIDH LKRRLKNFRW DALRCDQTGY YVVFASTKHG EDEAVRCFRE
410 420 430 440 450
CHMKPLFTYV MNMECQQYGD PDYERSPSPE RVMADKKRKA IEDRMDQEES
460 470 480 490 500
ADLELEKTQR AEAMDPVVAA LEQLKQELQE KILGDIKTRI AAPTLLELMQ
510 520 530 540 550
PERHVEKRRR LNIAEPRKKE EDIRPPSLLV PGLDPFGAGT PKSRAAGFSG
560 570 580 590 600
RGRKALGPYD RNRPGKKPPR IVNAFADERR KASAPKPRVA RGLHRQMIEM
610 620 630 640 650
FEGPEESDDE SRSNLTRGTE EQESRPISRA PSTDVEEEEE ESSRAHRAKR
660 670 680 690 700
RRIEAGWGED SDDEMMDDSH ARSLLAHCIH KDPENMAEKE LEQVLAILPR
710 720 730 740 750
SSPIWKKADK ALKGFRRLRK IEQEADAIFG VETSPVDKLD PEVIVTQDDE
760 770 780 790 800
PSKPIETTEL PETLKSLKKK QAAAKPKKKT KKQLEEEAKS AKAEVTEISL
810 820 830 840 850
PEEDIAEVKE HALVPEVSVT EDTPEEDDTG SVMWGVSSTE PRKTVEDDFS
860 870 880 890 900
VVMDIDGWQH MLKDEEDLLH LKAALQSIEA AKIGDAQSWA WKQKSIKHLN
910 920 930 940 950
RPGGEEGVSR TETKIEGYYV PNPTGSARTE GVKKIRESEK SKYLPHRIRV
960 970 980 990 1000
QREREERQRQ AKKAEHAVIS VEGFKFTTSS QKASTANSRA NRANNRRMVN
1010 1020 1030 1040 1050
DINISKNMTG AEGDALRFNQ LKKRKKLVKF DRSAIHNWGL YAQENIVAND
1060 1070 1080 1090 1100
MIIEYVGEKV RQRVADLREV RYDQQGVGSS YLFRIDEDTV IDATKMGGIA
1110 1120 1130 1140 1150
RFINHSCTPN CTAKIIRVDN TKRIVIYALR DIGQDEELTY DYKFEREMDA
1160
TDRIPCLCGS VGCKGFLN
Length:1,168
Mass (Da):130,831
Last modified:September 5, 2006 - v1
Checksum:i7E8780CBF58846D8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH445329 Genomic DNA. Translation: EAT89008.1.
RefSeqiXP_001794349.1. XM_001794297.1.

Genome annotation databases

EnsemblFungiiSNOT_03803; SNOT_03803; SNOG_03803.
GeneIDi5971212.
KEGGipno:SNOG_03803.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH445329 Genomic DNA. Translation: EAT89008.1 .
RefSeqi XP_001794349.1. XM_001794297.1.

3D structure databases

ProteinModelPortali Q0UWR1.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii SNOT_03803 ; SNOT_03803 ; SNOG_03803 .
GeneIDi 5971212.
KEGGi pno:SNOG_03803.

Phylogenomic databases

InParanoidi Q0UWR1.
KOi K11422.
OMAi DKTGYYI.
OrthoDBi EOG7P8PH3.

Family and domain databases

Gene3Di 3.30.70.330. 1 hit.
InterProi IPR024657. COMPASS_Set1_N-SET.
IPR017111. Hist_H3-K4_MeTrfase_1_fun.
IPR012677. Nucleotide-bd_a/b_plait.
IPR003616. Post-SET_dom.
IPR000504. RRM_dom.
IPR024636. SET_assoc.
IPR001214. SET_dom.
[Graphical view ]
Pfami PF11764. N-SET. 1 hit.
PF00076. RRM_1. 1 hit.
PF00856. SET. 1 hit.
PF11767. SET_assoc. 1 hit.
[Graphical view ]
PIRSFi PIRSF037104. Histone_H3-K4_mtfrase_Set1_fun. 1 hit.
SMARTi SM00508. PostSET. 1 hit.
SM00360. RRM. 1 hit.
SM00317. SET. 1 hit.
[Graphical view ]
PROSITEi PS50868. POST_SET. 1 hit.
PS50102. RRM. 1 hit.
PS51572. SAM_MT43_1. 1 hit.
PS50280. SET. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Dothideomycete-plant interactions illuminated by genome sequencing and EST analysis of the wheat pathogen Stagonospora nodorum."
    Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L., Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E., Torriani S.F.F., McDonald B.A., Oliver R.P.
    Plant Cell 19:3347-3368(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SN15 / ATCC MYA-4574 / FGSC 10173Imported.

Entry informationi

Entry nameiQ0UWR1_PHANO
AccessioniPrimary (citable) accession number: Q0UWR1
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: October 29, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3