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Q0UWR1

- Q0UWR1_PHANO

UniProt

Q0UWR1 - Q0UWR1_PHANO

Protein

Histone-lysine N-methyltransferase, H3 lysine-4 specific

Gene

SNOG_03803

Organism
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (05 Sep 2006)
      Previous versions | rss
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    Functioni

    Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.UniRule annotation

    Catalytic activityi

    S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].UniRule annotationSAAS annotation

    GO - Molecular functioni

    1. histone-lysine N-methyltransferase activity Source: UniProtKB-EC
    2. nucleic acid binding Source: InterPro
    3. nucleotide binding Source: InterPro

    Keywords - Molecular functioni

    Chromatin regulatorUniRule annotation, MethyltransferaseUniRule annotationSAAS annotation, Transferase

    Keywords - Ligandi

    S-adenosyl-L-methionineUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histone-lysine N-methyltransferase, H3 lysine-4 specificUniRule annotation (EC:2.1.1.43UniRule annotation)
    Gene namesi
    ORF Names:SNOG_03803Imported
    OrganismiPhaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)Imported
    Taxonomic identifieri321614 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesPleosporomycetidaePleosporalesPleosporineaePhaeosphaeriaceaeParastagonospora
    ProteomesiUP000001055: Unassembled WGS sequence

    Subcellular locationi

    Nucleus UniRule annotation

    GO - Cellular componenti

    1. chromosome Source: UniProtKB-KW
    2. Set1C/COMPASS complex Source: InterPro

    Keywords - Cellular componenti

    ChromosomeUniRule annotation, NucleusUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Component of the COMPASS (Set1C) complex.UniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliQ0UWR1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SET domain.
    Contains 1 post-SET domain.UniRule annotation
    Contains SET domain.SAAS annotation
    Contains post-SET domain.SAAS annotation

    Phylogenomic databases

    KOiK11422.
    OMAiDKTGYYI.
    OrthoDBiEOG7P8PH3.

    Family and domain databases

    Gene3Di3.30.70.330. 1 hit.
    InterProiIPR024657. COMPASS_Set1_N-SET.
    IPR017111. Hist_H3-K4_MeTrfase_1_fun.
    IPR012677. Nucleotide-bd_a/b_plait.
    IPR003616. Post-SET_dom.
    IPR000504. RRM_dom.
    IPR024636. SET_assoc.
    IPR001214. SET_dom.
    [Graphical view]
    PfamiPF11764. N-SET. 1 hit.
    PF00076. RRM_1. 1 hit.
    PF00856. SET. 1 hit.
    PF11767. SET_assoc. 1 hit.
    [Graphical view]
    PIRSFiPIRSF037104. Histone_H3-K4_mtfrase_Set1_fun. 1 hit.
    SMARTiSM00508. PostSET. 1 hit.
    SM00360. RRM. 1 hit.
    SM00317. SET. 1 hit.
    [Graphical view]
    PROSITEiPS50868. POST_SET. 1 hit.
    PS50102. RRM. 1 hit.
    PS51572. SAM_MT43_1. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q0UWR1-1 [UniParc]FASTAAdd to Basket

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    MSRSGQAISL SALTPLTTSS PSPRSAKTSY DTMNGTSSSR AAPSSAPENV     50
    ANTITPVNTP PETRKSVFPA DGVMAKRILY DPYSDAKLEK KVRHSKPAQY 100
    KTVLDKGDPS PPPDPRLALA GYTSGSYILK PTAKSKLRIA PYIAKPYAFD 150
    NRISCGPGPA TQVVVTGFDP LTPDSQLRGF FSTYGDVESL RAEVHPDNGS 200
    PLGICLIKFR DTPQARGSVA IKASTSAKRA EREGSNQRLG QQVIKVHTDR 250
    EGRRCAKLVE LVVQKSRKQE ENIRAKAAAK AAKASALATP ATFDLPANVP 300
    KGPSGRGARP PIPVPREPLN KKAALSHLIE KDPIKPKLKR APYLFIAHQY 350
    VPVLSTTIDH LKRRLKNFRW DALRCDQTGY YVVFASTKHG EDEAVRCFRE 400
    CHMKPLFTYV MNMECQQYGD PDYERSPSPE RVMADKKRKA IEDRMDQEES 450
    ADLELEKTQR AEAMDPVVAA LEQLKQELQE KILGDIKTRI AAPTLLELMQ 500
    PERHVEKRRR LNIAEPRKKE EDIRPPSLLV PGLDPFGAGT PKSRAAGFSG 550
    RGRKALGPYD RNRPGKKPPR IVNAFADERR KASAPKPRVA RGLHRQMIEM 600
    FEGPEESDDE SRSNLTRGTE EQESRPISRA PSTDVEEEEE ESSRAHRAKR 650
    RRIEAGWGED SDDEMMDDSH ARSLLAHCIH KDPENMAEKE LEQVLAILPR 700
    SSPIWKKADK ALKGFRRLRK IEQEADAIFG VETSPVDKLD PEVIVTQDDE 750
    PSKPIETTEL PETLKSLKKK QAAAKPKKKT KKQLEEEAKS AKAEVTEISL 800
    PEEDIAEVKE HALVPEVSVT EDTPEEDDTG SVMWGVSSTE PRKTVEDDFS 850
    VVMDIDGWQH MLKDEEDLLH LKAALQSIEA AKIGDAQSWA WKQKSIKHLN 900
    RPGGEEGVSR TETKIEGYYV PNPTGSARTE GVKKIRESEK SKYLPHRIRV 950
    QREREERQRQ AKKAEHAVIS VEGFKFTTSS QKASTANSRA NRANNRRMVN 1000
    DINISKNMTG AEGDALRFNQ LKKRKKLVKF DRSAIHNWGL YAQENIVAND 1050
    MIIEYVGEKV RQRVADLREV RYDQQGVGSS YLFRIDEDTV IDATKMGGIA 1100
    RFINHSCTPN CTAKIIRVDN TKRIVIYALR DIGQDEELTY DYKFEREMDA 1150
    TDRIPCLCGS VGCKGFLN 1168
    Length:1,168
    Mass (Da):130,831
    Last modified:September 5, 2006 - v1
    Checksum:i7E8780CBF58846D8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH445329 Genomic DNA. Translation: EAT89008.1.
    RefSeqiXP_001794349.1. XM_001794297.1.

    Genome annotation databases

    EnsemblFungiiSNOT_03803; SNOT_03803; SNOG_03803.
    GeneIDi5971212.
    KEGGipno:SNOG_03803.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH445329 Genomic DNA. Translation: EAT89008.1 .
    RefSeqi XP_001794349.1. XM_001794297.1.

    3D structure databases

    ProteinModelPortali Q0UWR1.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii SNOT_03803 ; SNOT_03803 ; SNOG_03803 .
    GeneIDi 5971212.
    KEGGi pno:SNOG_03803.

    Phylogenomic databases

    KOi K11422.
    OMAi DKTGYYI.
    OrthoDBi EOG7P8PH3.

    Family and domain databases

    Gene3Di 3.30.70.330. 1 hit.
    InterProi IPR024657. COMPASS_Set1_N-SET.
    IPR017111. Hist_H3-K4_MeTrfase_1_fun.
    IPR012677. Nucleotide-bd_a/b_plait.
    IPR003616. Post-SET_dom.
    IPR000504. RRM_dom.
    IPR024636. SET_assoc.
    IPR001214. SET_dom.
    [Graphical view ]
    Pfami PF11764. N-SET. 1 hit.
    PF00076. RRM_1. 1 hit.
    PF00856. SET. 1 hit.
    PF11767. SET_assoc. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF037104. Histone_H3-K4_mtfrase_Set1_fun. 1 hit.
    SMARTi SM00508. PostSET. 1 hit.
    SM00360. RRM. 1 hit.
    SM00317. SET. 1 hit.
    [Graphical view ]
    PROSITEi PS50868. POST_SET. 1 hit.
    PS50102. RRM. 1 hit.
    PS51572. SAM_MT43_1. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Dothideomycete-plant interactions illuminated by genome sequencing and EST analysis of the wheat pathogen Stagonospora nodorum."
      Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L., Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E., Torriani S.F.F., McDonald B.A., Oliver R.P.
      Plant Cell 19:3347-3368(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SN15 / ATCC MYA-4574 / FGSC 10173Imported.

    Entry informationi

    Entry nameiQ0UWR1_PHANO
    AccessioniPrimary (citable) accession number: Q0UWR1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 5, 2006
    Last sequence update: September 5, 2006
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3