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Q0UVK7 (DAPB_PHANO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable dipeptidyl-aminopeptidase B

Short name=DPAP B
EC=3.4.14.5
Gene names
Name:DAPB
ORF Names:SNOG_04207
OrganismPhaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum) [Reference proteome]
Taxonomic identifier321614 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesPleosporomycetidaePleosporalesPleosporineaePhaeosphaeriaceaeParastagonospora

Protein attributes

Sequence length911 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline By similarity.

Catalytic activity

Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.

Subcellular location

Vacuole membrane; Single-pass type II membrane protein By similarity. Note: Lysosome-like vacuoles By similarity.

Sequence similarities

Belongs to the peptidase S9B family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 911911Probable dipeptidyl-aminopeptidase B
PRO_0000412158

Regions

Topological domain1 – 9797Cytoplasmic Potential
Transmembrane98 – 11821Helical; Signal-anchor for type II membrane protein; Potential
Topological domain119 – 911793Vacuolar Potential

Sites

Active site7551Charge relay system By similarity
Active site8321Charge relay system By similarity
Active site8651Charge relay system By similarity

Amino acid modifications

Glycosylation2681N-linked (GlcNAc...) Potential
Glycosylation5641N-linked (GlcNAc...) Potential
Glycosylation8091N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q0UVK7 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 2B7D140A51D8324E

FASTA911103,088
        10         20         30         40         50         60 
MPRPRAAKEE ETELLAQHQE SPRPSSDGSE ASASSISTTS LVLEHINDGG FNGARSKVSE 

        70         80         90        100        110        120 
KYTDDGNGDL GHARERFDIE DGKFHPLTPV DKKARRTLWI VGTICAVGWA LALVSFLMNG 

       130        140        150        160        170        180 
NYKHSSTRPH DPDASVTKGS GKKITLDNVL GGQFYPQSQS VSWIAGPKGE DGLLLEKGVS 

       190        200        210        220        230        240 
GKDYLVVEDI RSKGNTEAAG DKFTLMKKGN FQIGEDIFIY PSNVWPSADF KKVLVMSEQQ 

       250        260        270        280        290        300 
KNWRHSYTGL YWIFDVETQT GEPLDPENQS ARVQYASFSP QSDAVVFTRD NNLYLRKLDS 

       310        320        330        340        350        360 
QKVVKITHDG GSELFYGVPD WVYEEEVFQD NSATWWSEDG KYVAFLRTDE SMVPTYPVQY 

       370        380        390        400        410        420 
FVSRPSGKQP DAGKESYPEV REIKYPKAGA PNPIVTLQFY DIEKSEMFRV DIDNDFTDKD 

       430        440        450        460        470        480 
RLITEIVWAG KSGQVLVRET NRESDILKLI LIDVSKRTGK TIREENVAKL DGGWFEVSHK 

       490        500        510        520        530        540 
TTFIPADSSL GRANDGYIDS VIHEGYDHIG YFTPLDSDKP ILLTKGEWEV VEAPSRVDLK 

       550        560        570        580        590        600 
NNLVYYVSTE RGSMERHPYV VALNGTDKRE VMDHSGPAYY DSSFSTGGGY ALMSYQGPGI 

       610        620        630        640        650        660 
PWQKIVSTPS NTEKFEKVLE ENKALEKMVQ KHELPILKYQ TIDVDGFKLN VLERRPPHFS 

       670        680        690        700        710        720 
EKRKYPVLFY QYSGPGSQQV QRKFEVDFQS YIAANLGYIV VTVDGRGTGF LGRKLRCITR 

       730        740        750        760        770        780 
DNIGYYEAYD QIAAAKMWAA KKYVDAEKLA IWGWSYGGFT TLKTIEMDGG RTFKYGMAVA 

       790        800        810        820        830        840 
PVTDWRFYDS IYTERYMHTP QNNPTGYDNT SITDVHSLSQ NVRFLIMHGV ADDNVHMQNT 

       850        860        870        880        890        900 
LTLLDKLDVA GVENYDVHVF PDSDHSIYFH NAHKIVYDKL TWWLTNAFNG EWLKIQKVRP 

       910 
KAQADARSLG R 

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References

[1]"Dothideomycete-plant interactions illuminated by genome sequencing and EST analysis of the wheat pathogen Stagonospora nodorum."
Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L., Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E., Torriani S.F.F., McDonald B.A., Oliver R.P.
Plant Cell 19:3347-3368(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SN15 / ATCC MYA-4574 / FGSC 10173.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH445330 Genomic DNA. Translation: EAT87967.1.
RefSeqXP_001794630.1. XM_001794578.1.

3D structure databases

ProteinModelPortalQ0UVK7.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

MEROPSS09.006.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSNOT_04207; SNOT_04207; SNOG_04207.
GeneID5971498.
KEGGpno:SNOG_04207.

Phylogenomic databases

KOK01282.
OMAWQSRDQQ.
OrthoDBEOG72VHFG.

Family and domain databases

Gene3D2.140.10.30. 1 hit.
InterProIPR001375. Peptidase_S9.
IPR002469. Peptidase_S9B.
[Graphical view]
PfamPF00930. DPPIV_N. 1 hit.
PF00326. Peptidase_S9. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDAPB_PHANO
AccessionPrimary (citable) accession number: Q0UVK7
Entry history
Integrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: September 5, 2006
Last modified: April 16, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries