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Protein

Mitochondrial thiamine pyrophosphate carrier 1

Gene

TPC1

Organism
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial thiamine pyrophosphate carrier 1
Gene namesi
Name:TPC1
ORF Names:SNOG_04593
OrganismiPhaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum)
Taxonomic identifieri321614 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesPleosporomycetidaePleosporalesPleosporineaePhaeosphaeriaceaeParastagonospora
Proteomesi
  • UP000001055 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei17 – 38Helical; Name=1Sequence analysisAdd BLAST22
Transmembranei91 – 107Helical; Name=2Sequence analysisAdd BLAST17
Transmembranei127 – 147Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei182 – 199Helical; Name=4Sequence analysisAdd BLAST18
Transmembranei213 – 231Helical; Name=5Sequence analysisAdd BLAST19
Transmembranei286 – 303Helical; Name=6Sequence analysisAdd BLAST18

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003204711 – 321Mitochondrial thiamine pyrophosphate carrier 1Add BLAST321

Structurei

3D structure databases

ProteinModelPortaliQ0UUH1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati12 – 110Solcar 1Add BLAST99
Repeati121 – 207Solcar 2Add BLAST87
Repeati216 – 311Solcar 3Add BLAST96

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ0UUH1.
KOiK15108.
OMAiWKGNVPA.
OrthoDBiEOG092C3KDM.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR002067. Mit_carrier.
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
PfamiView protein in Pfam
PF00153. Mito_carr. 3 hits.
PRINTSiPR00926. MITOCARRIER.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 3 hits.

Sequencei

Sequence statusi: Complete.

Q0UUH1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEGVAQLKH EGSRQQVVVA GAAAGLVSRF VIAPLDVIKI RLQLQIHSLS
60 70 80 90 100
EPTSYRGLNG PVYKGTLGTL KQILRDEGVT GLWKGNIPAE LLYLTYGSVQ
110 120 130 140 150
FSAYTNISQM LDTIPAPYTL PSSANSFISG AGAGAAATTV TYPLDLLRTR
160 170 180 190 200
FAAQGKDRVY TSIVASLKSI AQHEGPTGFF RGLGAGVSQI VPYMGLFFAS
210 220 230 240 250
YESLKPVMAD SPLPLPLGSS DAVAGVVASV VSKTAVYPLD TTRKRLQVQG
260 270 280 290 300
PNRARYVHRN IPTYSGVLMT LQHIWKHEGR RGMYRGLTVS LLKAAPASAV
310 320
TMWTYERAMG IMVAFEKDGM E
Length:321
Mass (Da):34,541
Last modified:February 26, 2008 - v3
Checksum:i45D0473DE1921E92
GO

Sequence cautioni

The sequence EAT88353 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH445330 Genomic DNA. Translation: EAT88353.2. Sequence problems.
RefSeqiXP_001795006.1. XM_001794954.1.

Genome annotation databases

GeneIDi5971874.
KEGGipno:SNOG_04593.

Similar proteinsi

Entry informationi

Entry nameiTPC1_PHANO
AccessioniPrimary (citable) accession number: Q0UUH1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: June 7, 2017
This is version 64 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families