Q0UTC7 (Q0UTC7_PHANO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Delta-aminolevulinic acid dehydratase RuleBase RU000515
EC=4.2.1.24 RuleBase RU000515

Gene names

ORF Names:

SNOG_04987 EMBL EAT87378.1

Organism

Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)

Taxonomic identifier

321614 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Dothideomycetes › Pleosporomycetidae › Pleosporales › Pleosporineae › Phaeosphaeriaceae › Phaeosphaeria

Protein attributes

Sequence length	376 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2 5-aminolevulinate = porphobilinogen + 2 H2O. RuleBase RU000515
Subunit structure	Homooctamer By similarity. PIRSR PIRSR001415-3 RuleBase RU000515
Sequence similarities	Belongs to the ALADH family. RuleBase RU004161

Ontologies

Keywords
Biological process	Porphyrin biosynthesis RuleBase RU000515
Ligand	Metal-binding PIRSR PIRSR001415-3 Zinc PIRSR PIRSR001415-3
Molecular function	Lyase RuleBase RU000515
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	porphyrin-containing compound biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW porphobilinogen synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	246	1	Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
	Active site	299	1	Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
	Metal binding	169	1	Zinc; catalytic By similarity PIRSR PIRSR001415-3
	Metal binding	171	1	Zinc; catalytic By similarity PIRSR PIRSR001415-3
	Metal binding	179	1	Zinc; catalytic By similarity PIRSR PIRSR001415-3
	Binding site	256	1	Substrate 1 By similarity PIRSR PIRSR001415-2
	Binding site	268	1	Substrate 1 By similarity PIRSR PIRSR001415-2
	Binding site	326	1	Substrate 2 By similarity PIRSR PIRSR001415-2
	Binding site	365	1	Substrate 2 By similarity PIRSR PIRSR001415-2

Sequences

	Sequence		Length	Mass (Da)
	Q0UTC7 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 25F75A01DBCF93AB	FASTA	376	40,739
	10 20 30 40 50 60 MSFSSLVSDI AYRSSERPER PDYRTQVSEA RSTRSYASTA ATSVSIAGDI KSQLHGGYSH 70 80 90 100 110 120 PLSRAWQAEK QLTKSMLIYP LFISDQPDEE TLIPSLPNQH RRGLNKIVPY LTPLVAKGLK 130 140 150 160 170 180 SVILFGVPIA PGAKDALGTN ADDPKGPVIR AIRLLRRSFP DLFIVADVCL CEYTSHGHCG 190 200 210 220 230 240 ILRDDGSLNN ALSVERVSDV AMSYAMAGAH CVAPSDMNDG RIRAIKLKLI EAGIAHQILL 250 260 270 280 290 300 MSYSAKFSGC LYGPFRDAAG SVPSFGDRRC YQLPPGGRGL ARRAIVRDIN EGADIIMVKP 310 320 330 340 350 360 ASQYLDIISD AKELGKDMPV AAYQVSGEYA MIHAAAAAGV FDLRQMAEEA TQGILRAGAS 370 IVVSYFTPEF LDWLGN

References

[1]

"Dothideomycete-plant interactions illuminated by genome sequencing and EST analysis of the wheat pathogen Stagonospora nodorum." Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L., Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E., Torriani S.F.F., McDonald B.A., Oliver R.P. Plant Cell 19:3347-3368(2007) [PubMed: 18024570] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SN15 / ATCC MYA-4574 / FGSC 10173.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH445331 Genomic DNA. Translation: EAT87378.1.
RefSeq	XP_001795400.1. XM_001795348.1.
3D structure databases
ProteinModelPortal	Q0UTC7.
SMR	Q0UTC7. Positions 49-374.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	SNOT_04987; SNOT_04987; SNOG_04987.
GeneID	5972275.
KEGG	pno:SNOG_04987.
Phylogenomic databases
OMA	GAHCVAP.
OrthoDB	EOG454D75.
PhylomeDB	Q0UTC7.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR001731. Porphobilinogen_synth. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01698.
PANTHER	PTHR11458. AlaD_dehydratase. 1 hit.
Pfam	PF00490. ALAD. 1 hit. [Graphical view]
PIRSF	PIRSF001415. Porphbilin_synth. 1 hit.
PRINTS	PR00144. DALDHYDRTASE.
SMART	SM01004. ALAD. 1 hit. [Graphical view]
PROSITE	PS00169. D_ALA_DEHYDRATASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q0UTC7_PHANO

Accession

Primary (citable) accession number: Q0UTC7

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2006
Last sequence update:	September 5, 2006
Last modified:	January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)