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Q0U5H7 (CARA_PHANO) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Carbamoyl-phosphate synthase arginine-specific small chain

Short name=CPS-A
EC=6.3.5.5
Alternative name(s):
Arginine-specific carbamoyl-phosphate synthetase, glutamine chain
Gene names
Name:CPA1
ORF Names:SNOG_12987
OrganismPhaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)
Taxonomic identifier321614 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesPleosporomycetidaePleosporalesPleosporineaePhaeosphaeriaceaePhaeosphaeria

Protein attributes

Sequence length476 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 ATP + L-glutamine + HCO3- + H2O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate.

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.

Subunit structure

Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the CarA family.

Contains 1 glutamine amidotransferase type-1 domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 476476Carbamoyl-phosphate synthase arginine-specific small chain
PRO_0000290598

Regions

Domain228 – 415188Glutamine amidotransferase type-1

Sites

Active site3041Nucleophile By similarity
Active site3881 By similarity
Active site3901 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0U5H7 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: AEBD2D76D5F792E3

FASTA47652,138
        10         20         30         40         50         60 
MFSHLLKPAA RSAGLLGHVN RRYLATVHTN TAREIPKPSR KPTPISLENA TFTIKNGPIF 

        70         80         90        100        110        120 
SGKSFGAKAN ISGEAVFTTS LVGYPESMTD PSYRGQILVF TQPLIGNYGV PSSARDEHGL 

       130        140        150        160        170        180 
LRYFESPNIQ ASGIVVQDYA LKHSHWTAVE SLAQWCAREG VPAISGVDTR EVVTYLREQG 

       190        200        210        220        230        240 
SSLARITVGE EYDADEDEAY IDPEAINLVR RVSTKAPFHV SSSLGDMHVA LIDCGVKENI 

       250        260        270        280        290        300 
LRSLVSRGAS VTCFPFDYPI HKVAHHFDGV FISNGPGDPT HCTSTVYNLR KLFETSQLPV 

       310        320        330        340        350        360 
MGICMGHQLI ALAAGAKTIK LKYGNRAHNI PALDLTTGKC HITSQNHGYA VDPTTLTSEW 

       370        380        390        400        410        420 
KEYFTNLNDQ SNEGLIHASR PIFSAQFHPE AKGGPMDSSY LFDKYIQNVQ RYKDHQSSFS 

       430        440        450        460        470 
EKSNKPSPLL VDLLSKERVG VHPAQPDFEM HVPGRVEQVD VGGPVAPPYQ PITAAA 

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References

[1]"Dothideomycete-plant interactions illuminated by genome sequencing and EST analysis of the wheat pathogen Stagonospora nodorum."
Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L., Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E., Torriani S.F.F., McDonald B.A., Oliver R.P.
Plant Cell 19:3347-3368(2007) [PubMed: 18024570] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SN15 / ATCC MYA-4574 / FGSC 10173.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH445348 Genomic DNA. Translation: EAT79787.1.
RefSeqXP_001803201.1. XM_001803149.1.

3D structure databases

ProteinModelPortalQ0U5H7.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSNOT_12987; SNOT_12987; SNOG_12987.
GeneID5980114.
KEGGpno:SNOG_12987.

Phylogenomic databases

OMAQNHSYVV.
OrthoDBEOG4N8VDH.
PhylomeDBQ0U5H7.

Family and domain databases

InterProIPR006274. CarbamoylP_synth_ssu.
IPR002474. CarbamoylP_synth_ssu_N.
IPR017926. GATASE_1.
[Graphical view]
Gene3DG3DSA:3.50.30.20. G3DSA:3.50.30.20. 1 hit.
KOK01956.
PfamPF00988. CPSase_sm_chain. 1 hit.
PF00117. GATase. 1 hit.
[Graphical view]
SMARTSM01097. CPSase_sm_chain. 1 hit.
[Graphical view]
SUPFAMSSF52021. CP_synthsmall. 1 hit.
TIGRFAMsTIGR01368. CPSaseIIsmall. 1 hit.
PROSITEPS51273. GATASE_TYPE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCARA_PHANO
AccessionPrimary (citable) accession number: Q0U5H7
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: September 5, 2006
Last modified: January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families