Q0U3B5 (Q0U3B5_PHANO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
mRNA-capping enzyme subunit alpha PIRNR PIRNR036959
EC=2.7.7.50 PIRNR PIRNR036959

Alternative name(s):
GTP--RNA guanylyltransferase PIRNR PIRNR036959
mRNA guanylyltransferase PIRNR PIRNR036959

Gene names

ORF Names:

SNOG_13749 EMBL EAT78773.1

Organism

Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)

Taxonomic identifier

321614 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Dothideomycetes › Pleosporomycetidae › Pleosporales › Pleosporineae › Phaeosphaeriaceae › Phaeosphaeria

Protein attributes

Sequence length	424 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate By similarity. PIRNR PIRNR036959
Catalytic activity	GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA. PIRNR PIRNR036959
Subunit structure	The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an RNA 5'-triphosphatase By similarity. PIRNR PIRNR036959
Subcellular location	Nucleus By similarity PIRNR PIRNR036959.
Sequence similarities	Belongs to the eukaryotic GTase family. PIRNR PIRNR036959

Ontologies

Keywords
Biological process	mRNA capping PIRNR PIRNR036959 mRNA processing
Cellular component	Nucleus PIRNR PIRNR036959
Ligand	GTP-binding PIRNR PIRNR036959 Nucleotide-binding
Molecular function	Nucleotidyltransferase PIRNR PIRNR036959 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	mRNA capping Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	mRNA cap methyltransferase complex Inferred from electronic annotation. Source: InterPro
Molecular function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW mRNA guanylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0U3B5 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 488BB74AF8FB0783	FASTA	424	48,921
	10 20 30 40 50 60 MPSIVTSHAP PPPMPGFQVP NDDASYLKGV VADILQRDNM RFPGAQPVSF AREHVAELKR 70 80 90 100 110 120 QEYFMCEKTD GLRCLLFIHW QQDHNGNPQP ATYLIDRKNN YYQLQPPLRI PYYKDPTNPE 130 140 150 160 170 180 PFLYGTILDG ELVHDQYPNE ATPRLNFYIF DALAVDSENL TGKTLDKRLG RFQEWVLKPY 190 200 210 220 230 240 HKKLTSTPNP DLRPFALKEK KTYPAYSIRQ MFDNVLPTLK HGNDGLIFTC KSTRYEFGTD 250 260 270 280 290 300 RHILKWKPPH ENTIDFKLRI GEFPLMDPMD GEEGLIPDYD AMPTSFELLV LHNNSNYERF 310 320 330 340 350 360 ANLAITPAEW EILKSLEQQL DGRIIECYRN LDGQWKFKAD GDGTPRWRDD KKDANHISTV 370 380 390 400 410 420 KSVLESIESP VTEDMLLQNE EGIKKAVYTI QGRADKYQPP SQQDGERDAK KRKFNETTSN GGAH

References

[1]

"Dothideomycete-plant interactions illuminated by genome sequencing and EST analysis of the wheat pathogen Stagonospora nodorum." Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L., Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E., Torriani S.F.F., McDonald B.A., Oliver R.P. Plant Cell 19:3347-3368(2007) [PubMed: 18024570] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: SN15 / ATCC MYA-4574 / FGSC 10173.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH445352 Genomic DNA. Translation: EAT78773.1.
RefSeq	XP_001803956.1. XM_001803904.1.
3D structure databases
ProteinModelPortal	Q0U3B5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	SNOT_13749; SNOT_13749; SNOG_13749.
GeneID	5980878.
KEGG	pno:SNOG_13749.
Phylogenomic databases
OMA	GSQPVSF.
OrthoDB	EOG4RV611.
PhylomeDB	Q0U3B5.
Family and domain databases
InterPro	IPR001339. mRNA_cap_enzyme. IPR013846. mRNA_cap_enzyme_C. IPR017075. mRNA_capping_enz_asu. IPR012340. NA-bd_OB-fold. IPR016027. NA-bd_OB-fold-like. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
KO	K00987.
Pfam	PF03919. mRNA_cap_C. 1 hit. PF01331. mRNA_cap_enzyme. 1 hit. [Graphical view]
PIRSF	PIRSF036959. mRNA_cap_alpha. 1 hit.
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q0U3B5_PHANO

Accession

Primary (citable) accession number: Q0U3B5

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2006
Last sequence update:	September 5, 2006
Last modified:	January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)