SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q0TXL7

- PMIP_PHANO

UniProt

Q0TXL7 - PMIP_PHANO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Mitochondrial intermediate peptidase

Gene
OCT1, SNOG_15771
Organism
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane By similarity.

Catalytic activityi

Release of an N-terminal octapeptide as second stage of processing of some proteins imported into the mitochondrion.

Cofactori

Binds 1 zinc ion By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi570 – 5701Zinc; catalytic By similarity
Active sitei571 – 5711 By similarity
Metal bindingi574 – 5741Zinc; catalytic By similarity
Metal bindingi577 – 5771Zinc; catalytic By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. metalloendopeptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Metalloprotease, Protease

Keywords - Ligandi

Metal-binding, Zinc

Protein family/group databases

MEROPSiM03.006.

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial intermediate peptidase (EC:3.4.24.59)
Short name:
MIP
Alternative name(s):
Octapeptidyl aminopeptidase
Gene namesi
Name:OCT1
ORF Names:SNOG_15771
OrganismiPhaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)
Taxonomic identifieri321614 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesPleosporomycetidaePleosporalesPleosporineaePhaeosphaeriaceaeParastagonospora
ProteomesiUP000001055: Unassembled WGS sequence

Subcellular locationi

Mitochondrion matrix By similarity

GO - Cellular componenti

  1. mitochondrial matrix Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 2929Mitochondrion Reviewed predictionAdd
BLAST
Chaini30 – 790761Mitochondrial intermediate peptidasePRO_0000338591Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ0TXL7.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M3 family.

Keywords - Domaini

Transit peptide

Phylogenomic databases

KOiK01410.
OrthoDBiEOG71GB4R.

Family and domain databases

Gene3Di1.10.1370.10. 2 hits.
3.40.390.10. 2 hits.
InterProiIPR024079. MetalloPept_cat_dom.
IPR024077. Neurolysin/TOP_dom2.
IPR001567. Pept_M3A_M3B.
[Graphical view]
PfamiPF01432. Peptidase_M3. 1 hit.
[Graphical view]
PROSITEiPS00142. ZINC_PROTEASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q0TXL7-1 [UniParc]FASTAAdd to Basket

« Hide

MLKRLARNNS SPWICSRCLQ QSQRQRRFNS TFAATATARD HAPSALYGLS    50
ASGKTDDDAL RKVFDNASFW ESFKRGTSNK KPSGIIGNKY LTHPDGFIDF 100
VTVTIQRCNG VVEKVSRAET IEDFKYMVKD LDKLSDLLCR VIDLADFVRS 150
THPNRQFQIM AVKAYHTVFQ YMNQLNTTPV LYDQLKKASD IPEVFESWTE 200
EERIVARILM EDFARFGIGL DDATRQKLVD LSGEIAEVGS QFVEGMSPET 250
PTLKFESKRL KGLDPNLAKA LTKWGETRIS TMHHEAQAVL RFVDDAEVRR 300
ETYSAVRTAG SSTIARLEKM LKLRAELAQL SGYETFSHMT LENKMAKTPE 350
AVNTFLKALY EDSRPSVLAD LHELMELKRG DAHQDNFPNR MNAWDKFYYT 400
QKMLSTMEGA YKQRTADSLS AYFSVGTVLQ GISRLFDRLY GVRLVPQETQ 450
PGEVWEDGVR RLDVISDTEG HIAVLYCDLF SRPGKTPNPA HFTLRCSREI 500
LPAELEEMQH MPHRFSSPIE AATDGMSVSY NASRNSYFQL PTIALICDFS 550
KPSSPRPTLL NIHDVRTLFH EMGHALHSIL GRTALQNVSG TRCATDIAEL 600
PSVLMEHFAF DPSVLALYAR HWDTNAPLPL ALLENRLAID NRNGYSELES 650
QILLAMLDQA YHSNLPLDPA FNSTSVYHNT YTRFASVPEP AGTRWQGFFG 700
HLFGYGATYY SYLFDRAIAS RIWKGVFNEG RDGGSLDREK GELYKNEVLR 750
WGGGRDGWVC LAGVLRDGKV GEGGEGAMRE VGKWGIDAGK 790
Length:790
Mass (Da):89,067
Last modified:February 5, 2008 - v2
Checksum:i3E8AFBC2E8963A45
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH445364 Genomic DNA. Translation: EAT76866.2.
RefSeqiXP_001805910.1. XM_001805858.1.

Genome annotation databases

EnsemblFungiiSNOT_15771; SNOT_15771; SNOG_15771.
GeneIDi5982840.
KEGGipno:SNOG_15771.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CH445364 Genomic DNA. Translation: EAT76866.2 .
RefSeqi XP_001805910.1. XM_001805858.1.

3D structure databases

ProteinModelPortali Q0TXL7.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi M03.006.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii SNOT_15771 ; SNOT_15771 ; SNOG_15771 .
GeneIDi 5982840.
KEGGi pno:SNOG_15771.

Phylogenomic databases

KOi K01410.
OrthoDBi EOG71GB4R.

Family and domain databases

Gene3Di 1.10.1370.10. 2 hits.
3.40.390.10. 2 hits.
InterProi IPR024079. MetalloPept_cat_dom.
IPR024077. Neurolysin/TOP_dom2.
IPR001567. Pept_M3A_M3B.
[Graphical view ]
Pfami PF01432. Peptidase_M3. 1 hit.
[Graphical view ]
PROSITEi PS00142. ZINC_PROTEASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Dothideomycete-plant interactions illuminated by genome sequencing and EST analysis of the wheat pathogen Stagonospora nodorum."
    Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L., Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E., Torriani S.F.F., McDonald B.A., Oliver R.P.
    Plant Cell 19:3347-3368(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SN15 / ATCC MYA-4574 / FGSC 10173.

Entry informationi

Entry nameiPMIP_PHANO
AccessioniPrimary (citable) accession number: Q0TXL7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: February 5, 2008
Last modified: May 14, 2014
This is version 51 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi