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Q0TX62 (Q0TX62_PHANO) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phosphogluconate dehydrogenase, decarboxylating PIRNR PIRNR000109 RuleBase RU000485
EC=1.1.1.44 PIRNR PIRNR000109 RuleBase RU000485
Gene names
ORF Names:SNOG_15879 EMBL EAT76717.1
OrganismPhaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Septoria nodorum)
Taxonomic identifier321614 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Dothideomycetes › Pleosporomycetidae › Pleosporales › Pleosporineae › Phaeosphaeriaceae › Phaeosphaeria

Protein attributes

Sequence length492 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH By similarity. PIRNR PIRNR000109

Catalytic activity

6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH. PIRNR PIRNR000109 RuleBase RU000485

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3. PIRNR PIRNR000109 RuleBase RU004281

Subunit structure

Homodimer By similarity. PIRNR PIRNR000109

Sequence similarities

Belongs to the 6-phosphogluconate dehydrogenase family. PIRNR PIRNR000109 RuleBase RU000485

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding12 – 176NADP By similarity PIRSR PIRSR000109-3
Nucleotide binding35 – 373NADP By similarity PIRSR PIRSR000109-3
Nucleotide binding77 – 793NADP By similarity PIRSR PIRSR000109-3
Region133 – 1353Substrate binding By similarity PIRSR PIRSR000109-2
Region190 – 1912Substrate binding By similarity PIRSR PIRSR000109-2

Sites

Active site1871Proton acceptor By similarity PIRSR PIRSR000109-1
Active site1941Proton donor By similarity PIRSR PIRSR000109-1
Binding site1071NADP By similarity PIRSR PIRSR000109-3
Binding site1071Substrate By similarity PIRSR PIRSR000109-2
Binding site1951Substrate By similarity PIRSR PIRSR000109-2
Binding site2641Substrate; via amide nitrogen By similarity PIRSR PIRSR000109-2
Binding site2911Substrate By similarity PIRSR PIRSR000109-2
Binding site4491Substrate; shared with dimeric partner By similarity PIRSR PIRSR000109-2
Binding site4551Substrate; shared with dimeric partner By similarity PIRSR PIRSR000109-2

Sequences

Sequence LengthMass (Da)Tools
Q0TX62 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 6E7EB00139EC274B

FASTA49253,963
        10         20         30         40         50         60 
MTEAVGDFGL IGLAVMGQNL ILNAADHGFT VVAFNRTVAK VDRFLNDEAK GKSIVGAHSI 

        70         80         90        100        110        120 
KEFVAKLKKP RRMMMLVMAG KPVDDFIELL LTEGGAEEGD IIIDGGNSHY PDTNRRTKYL 

       130        140        150        160        170        180 
ASKGIRFVGS GVSGGEEGAR YGPSIMPGGN EEAWPYIKDV LQSISAKSDG EACCQWVGDE 

       190        200        210        220        230        240 
GAGHYVKMVH NGIEYGDMQL ICEAYDIMKR GLGMSNKEMG DVFTEWNKGV LDSFLIEITR 

       250        260        270        280        290        300 
DIMYKNDDDG VAIVEKIMDS AGQKGTGKWT AINALDLGMP VTLIGEAVFA RCLSSLKSER 

       310        320        330        340        350        360 
GRAAGLLDGP SPSFSGDRKA FIDNLEQALY ASKIISYAQG FMLIQNAAKE YNWKLNKPEI 

       370        380        390        400        410        420 
ALMWRGGCII RSVFLKDITK AYRANPELEN LLFDDFFNKA IHKAQSGWRD VVSKGALWGI 

       430        440        450        460        470        480 
PTPAFSTALS FYDGYRAKDL PANLLQAQRD YFGAHTFRIK PECATEQYKV GQDIHVNWTG 

       490 
RGGNISASTY NA

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References

[1]"Dothideomycete-plant interactions illuminated by genome sequencing and EST analysis of the wheat pathogen Stagonospora nodorum."
Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L., Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E., Torriani S.F.F., McDonald B.A., Oliver R.P.
Plant Cell 19:3347-3368(2007) [PubMed: 18024570] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SN15 / ATCC MYA-4574 / FGSC 10173.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CH445365 Genomic DNA. Translation: EAT76717.1.
RefSeqXP_001806016.1. XM_001805964.1.

3D structure databases

ProteinModelPortalQ0TX62.
SMRQ0TX62. Positions 6-479.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSNOT_15879; SNOT_15879; SNOG_15879.
GeneID5982946.
KEGGpno:SNOG_15879.

Phylogenomic databases

OMAITKAYRE.
OrthoDBEOG4VDT6Z.
PhylomeDBQ0TX62.

Family and domain databases

InterProIPR008927. 6-PGluconate_DH_C-like.
IPR006114. 6PGDH_C.
IPR006113. 6PGDH_decarbox.
IPR006115. 6PGDH_NADP-bd.
IPR006184. 6PGdom_BS.
IPR013328. DH_multihelical.
IPR012284. Fibritin/6PGD_C-extension.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:1.20.5.320. Fibritin/6PGD_C-extension. 1 hit.
G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KOK00033.
PfamPF00393. 6PGD. 1 hit.
PF03446. NAD_binding_2. 1 hit.
[Graphical view]
PIRSFPIRSF000109. 6PGD. 1 hit.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMsTIGR00873. Gnd. 1 hit.
PROSITEPS00461. 6PGD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ0TX62_PHANO
AccessionPrimary (citable) accession number: Q0TX62
Entry history
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info