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Q0TUR6

- BGAL_CLOP1

UniProt

Q0TUR6 - BGAL_CLOP1

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Protein
Beta-galactosidase Pbg
Gene
pbg, CPF_0160
Organism
Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei118 – 1181Substrate By similarity
Metal bindingi122 – 1221Zinc By similarity
Binding sitei156 – 1561Substrate By similarity
Active sitei157 – 1571Proton donor By similarity
Metal bindingi162 – 1621Zinc By similarity
Metal bindingi164 – 1641Zinc By similarity
Metal bindingi167 – 1671Zinc By similarity
Active sitei318 – 3181Nucleophile By similarity
Binding sitei326 – 3261Substrate By similarity

GO - Molecular functioni

  1. beta-galactosidase activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. galactose metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciCPER195103:GHAW-169-MONOMER.

Protein family/group databases

CAZyiGH42. Glycoside Hydrolase Family 42.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidase Pbg (EC:3.2.1.23)
Short name:
Beta-gal
Gene namesi
Name:pbg
Ordered Locus Names:CPF_0160
OrganismiClostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A)
Taxonomic identifieri195103 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000001823: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. beta-galactosidase complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 689689Beta-galactosidase Pbg
PRO_0000407688Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi195103.CPF_0160.

Structurei

3D structure databases

ProteinModelPortaliQ0TUR6.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni366 – 3694Substrate binding

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1874.
HOGENOMiHOG000117811.
KOiK12308.
OMAiCFLGGFP.
OrthoDBiEOG6GTZGG.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
3.40.50.880. 1 hit.
InterProiIPR013739. Beta_galactosidase_C.
IPR013738. Beta_galactosidase_Trimer.
IPR029062. Class_I_gatase-like.
IPR013780. Glyco_hydro_13_b.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02449. Glyco_hydro_42. 1 hit.
PF08533. Glyco_hydro_42C. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view]
PIRSFiPIRSF001084. B-galactosidase. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52317. SSF52317. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0TUR6-1 [UniParc]FASTAAdd to Basket

« Hide

MKNYGPISSK VTKMLHGADY NPEQWIDMPN IWGEDVRLMK LSHTNVVAVG    50
IFSWTMLEPE EGKFNFEWLD EIMDLMHKNG NYVILATPSG AKPIWMAHKY 100
PETLRVAQNR VRNLYGERHN HCYTSPIYRE KIAIIDRLLA ERYKDHPALI 150
LWHISNEFEG QCYCPLCEEA FRDFLREKYD NDINKLNKAW WTKFWSHTYA 200
SFDEIEAPAP HGEPALHGLN LDWMRFVTHQ TLDYYKHERS ILKEITPDIP 250
VTTNFHDYIS LFRGIDYWKF APYLDVVSWD NYPYWHGERT DDHEGSRIGF 300
VHDLNRAILN GKPFMMMESS PSSTNWQPVA KLRRPGMHVL SSLQAVAHGS 350
DTVQYFQWRK SRGSSEKFHG AVVDHCGHEN TRVFRDVTKV GEILSKLDDV 400
IGTSVEPQVA VIYDWENYWA INDAQGPRIE QKDYFETCQK HYKAFWDMSI 450
PTDVINMDCD FSKYKVVVAP MLYMVRPGVG ERLEEFVKNG GTLVTTYWSG 500
IVDENDLCFL GGFPGPLKKV TGIWAEELDA LYDEDVNYVS VEEGNSLGMK 550
GEYEARIFCD LIHSEGAEVL ATYKTDFYKG MPALTCNNFG EGQAYYIAFR 600
NNDEFLSDFY SSLAKKLTLK RAIEIDLPKG INAQVRMDEK NEFVFFMNFS 650
SEEKTIDIKD LDLTDMVTGE KVAKEMEIEP YGVRIVRRK 689
Length:689
Mass (Da):79,981
Last modified:September 5, 2006 - v1
Checksum:i6034BFC444243857
GO

Sequence cautioni

The sequence BAA08485.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D49537 Genomic DNA. Translation: BAA08485.1. Different initiation.
CP000246 Genomic DNA. Translation: ABG83924.1.
RefSeqiYP_694624.1. NC_008261.1.

Genome annotation databases

EnsemblBacteriaiABG83924; ABG83924; CPF_0160.
GeneIDi4202873.
KEGGicpf:CPF_0160.
PATRICi19482617. VBICloPer106549_0147.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D49537 Genomic DNA. Translation: BAA08485.1 . Different initiation.
CP000246 Genomic DNA. Translation: ABG83924.1 .
RefSeqi YP_694624.1. NC_008261.1.

3D structure databases

ProteinModelPortali Q0TUR6.
ModBasei Search...

Protein-protein interaction databases

STRINGi 195103.CPF_0160.

Protein family/group databases

CAZyi GH42. Glycoside Hydrolase Family 42.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABG83924 ; ABG83924 ; CPF_0160 .
GeneIDi 4202873.
KEGGi cpf:CPF_0160.
PATRICi 19482617. VBICloPer106549_0147.

Phylogenomic databases

eggNOGi COG1874.
HOGENOMi HOG000117811.
KOi K12308.
OMAi CFLGGFP.
OrthoDBi EOG6GTZGG.

Enzyme and pathway databases

BioCyci CPER195103:GHAW-169-MONOMER.

Family and domain databases

Gene3Di 2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
3.40.50.880. 1 hit.
InterProi IPR013739. Beta_galactosidase_C.
IPR013738. Beta_galactosidase_Trimer.
IPR029062. Class_I_gatase-like.
IPR013780. Glyco_hydro_13_b.
IPR003476. Glyco_hydro_42.
IPR013529. Glyco_hydro_42_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF02449. Glyco_hydro_42. 1 hit.
PF08533. Glyco_hydro_42C. 1 hit.
PF08532. Glyco_hydro_42M. 1 hit.
[Graphical view ]
PIRSFi PIRSF001084. B-galactosidase. 1 hit.
SUPFAMi SSF51445. SSF51445. 1 hit.
SSF52317. SSF52317. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence analysis of flanking regions of the pfoA gene of Clostridium perfringens: beta-galactosidase gene (pbg) is located in the 3'-flanking region."
    Shimizu T., Kobayashi T., Ba-Thein W., Ohtani K., Hayashi H.
    Microbiol. Immunol. 39:677-686(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 13124 / NCTC 8237 / Type A.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13124 / NCTC 8237 / Type A.

Entry informationi

Entry nameiBGAL_CLOP1
AccessioniPrimary (citable) accession number: Q0TUR6
Secondary accession number(s): Q46253, Q59312
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 3, 2011
Last sequence update: September 5, 2006
Last modified: June 11, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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