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Q0TUR6

- BGAL_CLOP1

UniProt

Q0TUR6 - BGAL_CLOP1

Protein

Beta-galactosidase Pbg

Gene

pbg

Organism
Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 1 (05 Sep 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei118 – 1181SubstrateBy similarity
    Metal bindingi122 – 1221ZincBy similarity
    Binding sitei156 – 1561SubstrateBy similarity
    Active sitei157 – 1571Proton donorBy similarity
    Metal bindingi162 – 1621ZincBy similarity
    Metal bindingi164 – 1641ZincBy similarity
    Metal bindingi167 – 1671ZincBy similarity
    Active sitei318 – 3181NucleophileBy similarity
    Binding sitei326 – 3261SubstrateBy similarity

    GO - Molecular functioni

    1. beta-galactosidase activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. galactose metabolic process Source: InterPro

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciCPER195103:GHAW-169-MONOMER.

    Protein family/group databases

    CAZyiGH42. Glycoside Hydrolase Family 42.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Beta-galactosidase Pbg (EC:3.2.1.23)
    Short name:
    Beta-galBy similarity
    Gene namesi
    Name:pbgImported
    Ordered Locus Names:CPF_0160
    OrganismiClostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A)
    Taxonomic identifieri195103 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
    ProteomesiUP000001823: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. beta-galactosidase complex Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 689689Beta-galactosidase PbgPRO_0000407688Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi195103.CPF_0160.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0TUR6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni366 – 3694Substrate bindingBy similarity

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 42 family.Sequence Analysis

    Phylogenomic databases

    eggNOGiCOG1874.
    HOGENOMiHOG000117811.
    KOiK12308.
    OMAiCFLGGFP.
    OrthoDBiEOG6GTZGG.

    Family and domain databases

    Gene3Di2.60.40.1180. 1 hit.
    3.20.20.80. 1 hit.
    3.40.50.880. 1 hit.
    InterProiIPR013739. Beta_galactosidase_C.
    IPR013738. Beta_galactosidase_Trimer.
    IPR029062. Class_I_gatase-like.
    IPR013780. Glyco_hydro_13_b.
    IPR003476. Glyco_hydro_42.
    IPR013529. Glyco_hydro_42_N.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF02449. Glyco_hydro_42. 1 hit.
    PF08533. Glyco_hydro_42C. 1 hit.
    PF08532. Glyco_hydro_42M. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001084. B-galactosidase. 1 hit.
    SUPFAMiSSF51445. SSF51445. 1 hit.
    SSF52317. SSF52317. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q0TUR6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKNYGPISSK VTKMLHGADY NPEQWIDMPN IWGEDVRLMK LSHTNVVAVG    50
    IFSWTMLEPE EGKFNFEWLD EIMDLMHKNG NYVILATPSG AKPIWMAHKY 100
    PETLRVAQNR VRNLYGERHN HCYTSPIYRE KIAIIDRLLA ERYKDHPALI 150
    LWHISNEFEG QCYCPLCEEA FRDFLREKYD NDINKLNKAW WTKFWSHTYA 200
    SFDEIEAPAP HGEPALHGLN LDWMRFVTHQ TLDYYKHERS ILKEITPDIP 250
    VTTNFHDYIS LFRGIDYWKF APYLDVVSWD NYPYWHGERT DDHEGSRIGF 300
    VHDLNRAILN GKPFMMMESS PSSTNWQPVA KLRRPGMHVL SSLQAVAHGS 350
    DTVQYFQWRK SRGSSEKFHG AVVDHCGHEN TRVFRDVTKV GEILSKLDDV 400
    IGTSVEPQVA VIYDWENYWA INDAQGPRIE QKDYFETCQK HYKAFWDMSI 450
    PTDVINMDCD FSKYKVVVAP MLYMVRPGVG ERLEEFVKNG GTLVTTYWSG 500
    IVDENDLCFL GGFPGPLKKV TGIWAEELDA LYDEDVNYVS VEEGNSLGMK 550
    GEYEARIFCD LIHSEGAEVL ATYKTDFYKG MPALTCNNFG EGQAYYIAFR 600
    NNDEFLSDFY SSLAKKLTLK RAIEIDLPKG INAQVRMDEK NEFVFFMNFS 650
    SEEKTIDIKD LDLTDMVTGE KVAKEMEIEP YGVRIVRRK 689
    Length:689
    Mass (Da):79,981
    Last modified:September 5, 2006 - v1
    Checksum:i6034BFC444243857
    GO

    Sequence cautioni

    The sequence BAA08485.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D49537 Genomic DNA. Translation: BAA08485.1. Different initiation.
    CP000246 Genomic DNA. Translation: ABG83924.1.
    RefSeqiYP_694624.1. NC_008261.1.

    Genome annotation databases

    EnsemblBacteriaiABG83924; ABG83924; CPF_0160.
    GeneIDi4202873.
    KEGGicpf:CPF_0160.
    PATRICi19482617. VBICloPer106549_0147.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D49537 Genomic DNA. Translation: BAA08485.1 . Different initiation.
    CP000246 Genomic DNA. Translation: ABG83924.1 .
    RefSeqi YP_694624.1. NC_008261.1.

    3D structure databases

    ProteinModelPortali Q0TUR6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 195103.CPF_0160.

    Protein family/group databases

    CAZyi GH42. Glycoside Hydrolase Family 42.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABG83924 ; ABG83924 ; CPF_0160 .
    GeneIDi 4202873.
    KEGGi cpf:CPF_0160.
    PATRICi 19482617. VBICloPer106549_0147.

    Phylogenomic databases

    eggNOGi COG1874.
    HOGENOMi HOG000117811.
    KOi K12308.
    OMAi CFLGGFP.
    OrthoDBi EOG6GTZGG.

    Enzyme and pathway databases

    BioCyci CPER195103:GHAW-169-MONOMER.

    Family and domain databases

    Gene3Di 2.60.40.1180. 1 hit.
    3.20.20.80. 1 hit.
    3.40.50.880. 1 hit.
    InterProi IPR013739. Beta_galactosidase_C.
    IPR013738. Beta_galactosidase_Trimer.
    IPR029062. Class_I_gatase-like.
    IPR013780. Glyco_hydro_13_b.
    IPR003476. Glyco_hydro_42.
    IPR013529. Glyco_hydro_42_N.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF02449. Glyco_hydro_42. 1 hit.
    PF08533. Glyco_hydro_42C. 1 hit.
    PF08532. Glyco_hydro_42M. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001084. B-galactosidase. 1 hit.
    SUPFAMi SSF51445. SSF51445. 1 hit.
    SSF52317. SSF52317. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of flanking regions of the pfoA gene of Clostridium perfringens: beta-galactosidase gene (pbg) is located in the 3'-flanking region."
      Shimizu T., Kobayashi T., Ba-Thein W., Ohtani K., Hayashi H.
      Microbiol. Immunol. 39:677-686(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 13124 / NCTC 8237 / Type AImported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 13124 / NCTC 8237 / Type AImported.

    Entry informationi

    Entry nameiBGAL_CLOP1
    AccessioniPrimary (citable) accession number: Q0TUR6
    Secondary accession number(s): Q46253, Q59312
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 3, 2011
    Last sequence update: September 5, 2006
    Last modified: October 1, 2014
    This is version 49 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3