Q0TTV3 (Q0TTV3_CLOP1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
dTDP-glucose 4,6-dehydratase RuleBase RU004473
EC=4.2.1.46 RuleBase RU004473

Gene names

Name:	rfbB EMBL ABG82897.1
Ordered Locus Names:	CPF_0482

Organism

Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A) [Complete proteome] [HAMAP] EMBL ABG82897.1

Taxonomic identifier

195103 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium › Clostridium perfringens

Protein attributes

Sequence length	349 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O. RuleBase RU004473
Cofactor	NAD By similarity. RuleBase RU004473
Sequence similarities	Belongs to the sugar epimerase family. dTDP-glucose dehydratase subfamily. RuleBase RU004473

Ontologies

Keywords
Molecular function	Lyase RuleBase RU004473 EMBL ABG82897.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	nucleotide-sugar metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	coenzyme binding Inferred from electronic annotation. Source: InterPro dTDP-glucose 4,6-dehydratase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0TTV3 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: D3CB1AEB929364E4	FASTA	349	40,268
	10 20 30 40 50 60 MKTYLVTGGA GFIGSNFVLY MLKKYKDIKI INLDKLTYAG NLENLKSIEN DERHIFVQGD 70 80 90 100 110 120 ICDKELVSSL FEKYEIDYVA HFAAESHVDR SIREPEVFAK TNVLGTVNLL NCAKNAWETE 130 140 150 160 170 180 EGWKEGVKFL HVSTDEVYGS LGETGYFMET TPLDPHSPYS SSKASSDLMV KAYADTYKMP 190 200 210 220 230 240 VNITRCSNNY GPFQFPEKLI PLLINNCLNH KDLPVYGDGM NIRDWLFVED HAKAIDMVIN 250 260 270 280 290 300 GGRLGEVYNV GGHNERTNIQ IVKTVIEYLH DNVDEEITEN LIKYVEDRKG HDRRYGIDPT 310 320 330 340 KIKEELGWYP ETTFEVGIKK TIKWYLDNKE WMENVTSGDY QKYYEKMYK

References

[1]

"Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens." Myers G.S., Rasko D.A., Cheung J.K., Ravel J., Seshadri R., Deboy R.T., Ren Q., Varga J., Awad M.M., Brinkac L.M., Daugherty S.C., Haft D.H., Dodson R.J., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A., Khouri H. , Dimitrov G.I., Watkins K.L., Mulligan S., Benton J., Radune D., Fisher D.J., Atkins H.S., Hiscox T., Jost B.H., Billington S.J., Songer J.G., McClane B.A., Titball R.W., Rood J.I., Melville S.B., Paulsen I.T. Genome Res. 16:1031-1040(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13124 / NCTC 8237 / Type A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000246 Genomic DNA. Translation: ABG82897.1.
RefSeq	YP_694937.1. NC_008261.1.
3D structure databases
ProteinModelPortal	Q0TTV3.
ModBase	Search...
Protein-protein interaction databases
STRING	195103.CPF_0482.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABG82897; ABG82897; CPF_0482.
GeneID	4202087.
KEGG	cpf:CPF_0482.
PATRIC	19483268. VBICloPer106549_0462.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1088.
HOGENOM	HOG000168006.
KO	K01710.
OMA	LTYAGNY.
ProtClustDB	CLSK883116.
Enzyme and pathway databases
BioCyc	CPER195103:GHAW-497-MONOMER.
Family and domain databases
Gene3D	3.40.50.720. 1 hit.
InterPro	IPR005888. dTDP_Gluc_deHydtase. IPR001509. Epimerase_deHydtase. IPR016040. NAD(P)-bd_dom. [Graphical view]
PANTHER	PTHR10366:SF41. PTHR10366:SF41. 1 hit.
Pfam	PF01370. Epimerase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01181. dTDP_gluc_dehyt. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q0TTV3_CLOP1

Accession

Primary (citable) accession number: Q0TTV3

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2006
Last sequence update:	September 5, 2006
Last modified:	May 29, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)