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Protein

dTDP-glucose 4,6-dehydratase

Gene

rfbB

Organism
Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O.UniRule annotation

Cofactori

NAD(+)UniRule annotation

GO - Molecular functioni

  1. coenzyme binding Source: InterPro
  2. dTDP-glucose 4,6-dehydratase activity Source: UniProtKB-EC

GO - Biological processi

  1. nucleotide-sugar metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Enzyme and pathway databases

BioCyciCPER195103:GHAW-497-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
dTDP-glucose 4,6-dehydrataseUniRule annotation (EC:4.2.1.46UniRule annotation)
Gene namesi
Name:rfbBImported
Ordered Locus Names:CPF_0482Imported
OrganismiClostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A)Imported
Taxonomic identifieri195103 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000001823 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi195103.CPF_0482.

Structurei

3D structure databases

ProteinModelPortaliQ0TTV3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG1088.
HOGENOMiHOG000168006.
KOiK01710.
OMAiSETIDWY.
OrthoDBiEOG6PZXCX.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR005888. dTDP_Gluc_deHydtase.
IPR001509. Epimerase_deHydtase_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR10366:SF41. PTHR10366:SF41. 1 hit.
PfamiPF01370. Epimerase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01181. dTDP_gluc_dehyt. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0TTV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTYLVTGGA GFIGSNFVLY MLKKYKDIKI INLDKLTYAG NLENLKSIEN
60 70 80 90 100
DERHIFVQGD ICDKELVSSL FEKYEIDYVA HFAAESHVDR SIREPEVFAK
110 120 130 140 150
TNVLGTVNLL NCAKNAWETE EGWKEGVKFL HVSTDEVYGS LGETGYFMET
160 170 180 190 200
TPLDPHSPYS SSKASSDLMV KAYADTYKMP VNITRCSNNY GPFQFPEKLI
210 220 230 240 250
PLLINNCLNH KDLPVYGDGM NIRDWLFVED HAKAIDMVIN GGRLGEVYNV
260 270 280 290 300
GGHNERTNIQ IVKTVIEYLH DNVDEEITEN LIKYVEDRKG HDRRYGIDPT
310 320 330 340
KIKEELGWYP ETTFEVGIKK TIKWYLDNKE WMENVTSGDY QKYYEKMYK
Length:349
Mass (Da):40,268
Last modified:September 5, 2006 - v1
Checksum:iD3CB1AEB929364E4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000246 Genomic DNA. Translation: ABG82897.1.
RefSeqiYP_694937.1. NC_008261.1.

Genome annotation databases

EnsemblBacteriaiABG82897; ABG82897; CPF_0482.
KEGGicpf:CPF_0482.
PATRICi19483268. VBICloPer106549_0462.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000246 Genomic DNA. Translation: ABG82897.1.
RefSeqiYP_694937.1. NC_008261.1.

3D structure databases

ProteinModelPortaliQ0TTV3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi195103.CPF_0482.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG82897; ABG82897; CPF_0482.
KEGGicpf:CPF_0482.
PATRICi19483268. VBICloPer106549_0462.

Phylogenomic databases

eggNOGiCOG1088.
HOGENOMiHOG000168006.
KOiK01710.
OMAiSETIDWY.
OrthoDBiEOG6PZXCX.

Enzyme and pathway databases

BioCyciCPER195103:GHAW-497-MONOMER.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR005888. dTDP_Gluc_deHydtase.
IPR001509. Epimerase_deHydtase_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR10366:SF41. PTHR10366:SF41. 1 hit.
PfamiPF01370. Epimerase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01181. dTDP_gluc_dehyt. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13124 / NCTC 8237 / Type AImported.

Entry informationi

Entry nameiQ0TTV3_CLOP1
AccessioniPrimary (citable) accession number: Q0TTV3
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: April 1, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.