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Q0TTQ4 (Q0TTQ4_CLOP1) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:nanJ EMBL ABG84247.1
Ordered Locus Names:CPF_0532 EMBL ABG84247.1
OrganismClostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A) [Complete proteome] [HAMAP] EMBL ABG84247.1
Taxonomic identifier195103 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length1173 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 fibronectin type-III domain. RuleBase RU000718

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2251Calcium 1 PDB 2V73
Metal binding2261Calcium 1; via carbonyl oxygen PDB 2V73
Metal binding2811Calcium 1; via carbonyl oxygen PDB 2V73
Metal binding3301Calcium 2 PDB 2V73
Metal binding3311Calcium 2; via carbonyl oxygen PDB 2V73
Metal binding3371Calcium 2 PDB 2V73

Sequences

Sequence LengthMass (Da)Tools
Q0TTQ4 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: D5A7CC27735851FE

FASTA1,173128,883
        10         20         30         40         50         60 
MKSKKIIATL VASLVISNMG GYLVKANPNV NHKAVIIEDR QAIIETAIPQ SEMTASATSE 

        70         80         90        100        110        120 
EGQDPASSAI DGNTNTMWHT KWNGSDALPQ SLSVNLGSSR KVSSIAITPR TSGNNGFITK 

       130        140        150        160        170        180 
YEIHAINNGV EALVAEGTWE ENNLVKTVTF DSPIDAEEIK ITAIQGVGGF ASIAELNVYE 

       190        200        210        220        230        240 
IKGEVDEIAN YGNLKITKEE ERVNITGDLE KFSSLEEGTI VTRFNMNDTS IQSLIGLSDG 

       250        260        270        280        290        300 
NKANNYFSLY VSGGKVGYEL RRQEGNGDFN VHHSADVTFN RGINTLALKI EKGIGAKIFL 

       310        320        330        340        350        360 
NGSLVKTVSD PNIKFLNAIN LNSGFIGKTD RANGYNEYLF RGNIDFMNIY DKPVSDNYLL 

       370        380        390        400        410        420 
RKTGETKAPL EDSLLPDDVY KTQPVELFYP GYLESRGYRI PALETTKKGT VLASIDVRNN 

       430        440        450        460        470        480 
GDHDAPNNNI DVGIRRKEVN GEWEEGKVIL DYPGKSAAID TSLMSATIEE NGIEKERIFL 

       490        500        510        520        530        540 
IVTHFPEGYG FPNTEGGSGY REIDGKYYFI LKDAQNNEYT VREDGIVYNS EGNQTDYVMK 

       550        560        570        580        590        600 
NDKTLIQNGE EVGNALLSNS PLKAVGTAHI EMIYSDDDGK TWSEPEDLNP GLKKEWMKFF 

       610        620        630        640        650        660 
GTAPGKGIQI KNGEHKDRLI FPIYYTNQNN FQSSAVIYSD DFGETWKLGE SPIDTASVSS 

       670        680        690        700        710        720 
ETVSSGTQLT ECQVVEMPNG QLKLFMRNTG SYTRIATSFD GGATWHDEVP EDTSLREPYC 

       730        740        750        760        770        780 
QLSVINYSGK INGKDAIIFS NPDASSRVNG SVKVGLINEN GTYDNGEPRY EFDWIYNKTV 

       790        800        810        820        830        840 
KPGSFAYSCL TELPDGNLGL FYEGEGAGRM AYTEFDLNYL KFNASEDSPS ASVQSIEVLD 

       850        860        870        880        890        900 
EDLAYNSGEE VSIKVNFNQL VSIIGDRKIT LDIGGVDVPL NMVNYEGKSS AIFKGTIPEG 

       910        920        930        940        950        960 
INQGNYEIKL KENNTLELNT VYNKVSTFNG LDNTGINVQI GELKTTVGNS TIKVNDEVQV 

       970        980        990       1000       1010       1020 
GSAFEAILGI EGLNGDTEVY SAEYLFEYNA EAFILNEITS FNDSLFVKSK EVEPGKVRIL 

      1030       1040       1050       1060       1070       1080 
VASLGNEIEK DSDLVKVNLT PKISSELEVL GLTTALVGAG DGNTHDLELS SKEVKINEEA 

      1090       1100       1110       1120       1130       1140 
SGEIVVNPVQ NFEIPEINKK NVKLTWNAPI TTEGLEGYVI YKDGKKLSEV PAESTEFVVS 

      1150       1160       1170 
KLNRHTIYNF KVAAKYSNGE LSAKESKTIR TAR 

« Hide

References

« Hide 'large scale' references
[1]"Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens."
Myers G.S., Rasko D.A., Cheung J.K., Ravel J., Seshadri R., Deboy R.T., Ren Q., Varga J., Awad M.M., Brinkac L.M., Daugherty S.C., Haft D.H., Dodson R.J., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A., Khouri H. expand/collapse author list , Dimitrov G.I., Watkins K.L., Mulligan S., Benton J., Radune D., Fisher D.J., Atkins H.S., Hiscox T., Jost B.H., Billington S.J., Songer J.G., McClane B.A., Titball R.W., Rood J.I., Melville S.B., Paulsen I.T.
Genome Res. 16:1031-1040(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 13124 / NCTC 8237 / Type A.
[2]"Carbohydrate recognition by a large sialidase toxin from Clostridium perfringens."
Boraston A.B., Ficko-Blean E., Healey M.
Biochemistry 46:11352-11360(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) OF 181-367 IN COMPLEX WITH CALCIUM.
[3]"Structural basis of Clostridium perfringens toxin complex formation."
Adams J.J., Gregg K., Bayer E.A., Boraston A.B., Smith S.P.
Proc. Natl. Acad. Sci. U.S.A. 105:12194-12199(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) OF 939-1081.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000246 Genomic DNA. Translation: ABG84247.1.
RefSeqYP_694986.1. NC_008261.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2V73X-ray2.20A/B181-367[»]
2VO8X-ray1.70A939-1081[»]
ProteinModelPortalQ0TTQ4.
SMRQ0TTQ4. Positions 44-180, 185-367, 378-821.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING195103.CPF_0532.

Protein family/group databases

CAZyCBM32. Carbohydrate-Binding Module Family 32.
CBM40. Carbohydrate-Binding Module Family 40.
GH33. Glycoside Hydrolase Family 33.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABG84247; ABG84247; CPF_0532.
GeneID4202243.
KEGGcpf:CPF_0532.
PATRIC19483368. VBICloPer106549_0511.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG4409.
HOGENOMHOG000120093.
KOK01186.
OMAEMTASAT.
OrthoDBEOG61CM2G.

Enzyme and pathway databases

BioCycCPER195103:GHAW-547-MONOMER.

Family and domain databases

Gene3D2.120.10.10. 2 hits.
2.60.120.200. 1 hit.
2.60.120.260. 1 hit.
2.60.40.10. 1 hit.
InterProIPR008965. Carb-bd_dom.
IPR000421. Coagulation_fac_5/8-C_type_dom.
IPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR003961. Fibronectin_type3.
IPR008979. Galactose-bd-like.
IPR004124. Glyco_hydro_33_N.
IPR013783. Ig-like_fold.
IPR026856. Sialidase_fam.
IPR021984. Sialidase_pen_C.
IPR011040. Sialidases.
[Graphical view]
PANTHERPTHR10628. PTHR10628. 1 hit.
PfamPF00754. F5_F8_type_C. 1 hit.
PF00041. fn3. 1 hit.
PF02973. Sialidase. 1 hit.
PF12135. Sialidase_penC. 1 hit.
[Graphical view]
SMARTSM00060. FN3. 1 hit.
[Graphical view]
SUPFAMSSF49265. SSF49265. 1 hit.
SSF49384. SSF49384. 1 hit.
SSF49785. SSF49785. 1 hit.
SSF49899. SSF49899. 1 hit.
SSF50939. SSF50939. 2 hits.
PROSITEPS50022. FA58C_3. 1 hit.
PS50853. FN3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ0TTQ4.

Entry information

Entry nameQ0TTQ4_CLOP1
AccessionPrimary (citable) accession number: Q0TTQ4
Entry history
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: June 11, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)