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Q0TST1 (Q0TST1_CLOP1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesSubmitted name:
Alpha-N-acetylglucosaminidase family protein EMBL ABG84150.1
Gene names
Ordered Locus Names:CPF_0859
OrganismClostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A) [Complete proteome] [HAMAP]
Taxonomic identifier195103 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length2095 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 fibronectin type-III domain. RuleBase RU000718

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region299 – 3013N-acetyl-D-glucosamine binding PDB 2VCA

Sites

Metal binding481Calcium; via carbonyl oxygen PDB 2VC9 PDB 2VCA PDB 2VCB PDB 2VCC
Metal binding511Calcium PDB 2VC9 PDB 2VCA PDB 2VCB PDB 2VCC
Metal binding531Calcium; via carbonyl oxygen PDB 2VC9 PDB 2VCA PDB 2VCB PDB 2VCC
Metal binding561Calcium PDB 2VC9 PDB 2VCA PDB 2VCB PDB 2VCC
Metal binding1481Calcium; via carbonyl oxygen PDB 2VC9 PDB 2VCA PDB 2VCB PDB 2VCC
Metal binding1491Calcium PDB 2VC9 PDB 2VCA PDB 2VCB PDB 2VCC
Binding site3051N-acetyl-D-glucosamine PDB 2VCA
Binding site3661N-acetyl-D-glucosamine PDB 2VCA
Binding site4821N-acetyl-D-glucosamine PDB 2VCA
Binding site5171N-acetyl-D-glucosamine PDB 2VCA
Binding site6011N-acetyl-D-glucosamine PDB 2VCA
Binding site8251N-acetyl-D-glucosamine PDB 2VCA

Sequences

Sequence LengthMass (Da)Tools
Q0TST1 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 491A92947AC7F54F

FASTA2,095234,565
        10         20         30         40         50         60 
MAYVLASTFV FGLVNPSAIK VRASTGVEIT EGVTVTAKGN TEGNTADLAI DGDLSTYWES 

        70         80         90        100        110        120 
SNDYKWIEVD LGGIYELSKI EIFNKDEAVY KYNIYASEDG ENFNKIAYKN NDNVSDSNGN 

       130        140        150        160        170        180 
MHTIDNVRAG KIRIDVVQNS NSDRVNIAEI NVFGKNTGES LPEVKKIATS NFSETPWATE 

       190        200        210        220        230        240 
YEKFNSDSAY ANEKTLNEIK NLVGRVIGRE FKDKFIFEIR DQLNGNDVFE VSDSGDGKVL 

       250        260        270        280        290        300 
IKGNNGVSLA SGFNYYLKNY CNVSYNPIMG SNLKMPETMP SVGERVVIDT PYEHRYALNF 

       310        320        330        340        350        360 
CTYSYTMSFW DWDQYEEFLD WCAMNGVNLV LDIIGQEEVL RRTLNEFGYS DEEVKEFISG 

       370        380        390        400        410        420 
PAYFAWFYMQ NMTGFGGPLP NDWFEQRAEL GRKMHDRMQS FGINPVLQGY SGMVPRDFKE 

       430        440        450        460        470        480 
KNQEAQTISQ GGWCGFDRPD MLKTYVNEGE ADYFQKVADV FYEKQKEVFG DVTNFYGVDP 

       490        500        510        520        530        540 
FHEGGNTGDL DNGKIYEIIQ NKMIEHDNDA VWVIQNWQGN PSNNKLEGLT KKDQAMVLDL 

       550        560        570        580        590        600 
FSEVSPDWNR LEERDLPWIW NMLHNFGGRM GMDAAPEKLA TEIPKALANS EHMVGIGITP 

       610        620        630        640        650        660 
EAINTNPLAY ELLFDMAWTR DQINFRTWTE DYIERRYGKT NKEILEAWNI ILDTAYKKRN 

       670        680        690        700        710        720 
DYYQGAAESI INARPGFGIK SASTWGHSKI VYDKSEFEKA IEIFAKNYDE FKDSDAFLYD 

       730        740        750        760        770        780 
FADILKQLLA NSAQEYYEVM CNAYNNGNGE KFKFVSGKFL ELIKLQERVL STRPEFLIGN 

       790        800        810        820        830        840 
WIEDARTMLK DSDDWTKDLF EFNARALVTT WGSRNNADGG GLKDYSNRQW SGLTEDYYYA 

       850        860        870        880        890        900 
RWEKWINGLQ AELDGGAKAP NIDWFKMEYD WVNKKSDTDK LYPTEASNEN LGELAKIAME 

       910        920        930        940        950        960 
SYSVTNMDKI LGENESVERV NIALGKPVSS ETHEETEADP LSNITDGNTG TMWIADREGY 

       970        980        990       1000       1010       1020 
PASVTVDLQG VKSVDGIEFA FRNQAGDRAV AYKVEVMDES GQWKIVSDKS EDYSSKGVIE 

      1030       1040       1050       1060       1070       1080 
KVDFTGKAQK VKVSLTNVDL NLSPSYKIPE LAEIMVYGGK EKEDEYTNVA LGKTVTGAEA 

      1090       1100       1110       1120       1130       1140 
ENGKSLSNIT DGDLNSLWVS NGGKTPATTS IDLQGTENVE FLELHFEKPG LRFQFKVEVE 

      1150       1160       1170       1180       1190       1200 
DANGNKENVL DMTSNKEDNE KSYKIPVGKD INKVHVTMTG KAEGGQHPGA WAAIAEVKAM 

      1210       1220       1230       1240       1250       1260 
SKEKPANYVN IAENKNVSGS NSQSGNPLSN ITDGDLSSLW ISDNGAMPAN ATIDLEGNNF 

      1270       1280       1290       1300       1310       1320 
VDFLELHFEK EGFRFQFKVE VEDESGNRET VLDMTSNTED NKKSYNIPVK KEISKIHATI 

      1330       1340       1350       1360       1370       1380 
TGKAPGGSFD QAWAAIAEIK AMSKEAINKV EQASIALPQG NMKATATSEH PDVGNEGLAK 

      1390       1400       1410       1420       1430       1440 
FAIDGKENTI WHTKYNPVEE LPQSITLELG GSYEINKFTY LPRSGAKNGN ITKYELHVSE 

      1450       1460       1470       1480       1490       1500 
DGNNFRKISE GNWDDSGSLK TLKFNSTKAT HVKLVALEGV GGFASAAELN VFAIPENLAM 

      1510       1520       1530       1540       1550       1560 
KDETKVEVTS NNSEANNLRD GNENTLWVPG QEEEKSVTFD LSKEKDISAI DIVSKGNSPL 

      1570       1580       1590       1600       1610       1620 
KYSIEISNDG TEWTKIVDEN NNEENKAVYS NILKSGKIGR FVRFNFNSEN VKIGEIKIYK 

      1630       1640       1650       1660       1670       1680 
GDSTSSLASY IRVVEDIYNS AVVGDMAGNY TEEAKESLGN AINEAKLALG NDINSKEANE 

      1690       1700       1710       1720       1730       1740 
VMSTLKSALN EFYKGFVQIN RTKLAALISD VDILLNEILP SLMNSMNYNE KAIVNAEIQK 

      1750       1760       1770       1780       1790       1800 
LKLENNEAKE VYNKKQVSQS EIDTAYDELK NTLDSYYDAV SAETAYKSMV LLAKEKVENA 

      1810       1820       1830       1840       1850       1860 
VVGNGNGQYP KEAVDALNEA IRIAEEGFES STSLEEIRNI TKTLKEAIDT FVESVNVIDK 

      1870       1880       1890       1900       1910       1920 
AQLEEIISSI ESKLENAEGV YIPNAIEELK KALDKAKEVL NNEGANEEDI NKAISDLTEA 

      1930       1940       1950       1960       1970       1980 
EANFELSKVP NKDELNSEIE RAYDVLEKLK GFEHLEGIKI KLEDAILEAE RVKNDENSLK 

      1990       2000       2010       2020       2030       2040 
VDVDKVLGEL KIVIEEALKA IDSSEVIVCP VRDFKATNIS KKTVTVQWSA PENSFGLEGY 

      2050       2060       2070       2080       2090 
VLYKDGKKVA ELGKDETTYK FKGLNRHTIY NFKIAAKYNN GELSSKESIT LRTER

« Hide

References

« Hide 'large scale' references
[1]"Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens."
Myers G.S.A., Rasko D.A., Cheung J.K., Ravel J., Seshadri R., DeBoy R.T., Ren Q., Varga J., Awad M.M., Brinkac L.M., Daugherty S.C., Haft D.H., Dodson R.J., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A., Khouri H. expand/collapse author list , Dimitrov G.I., Watkins K.L., Mulligan S., Benton J., Radune D., Fisher D.J., Atkins H.S., Hiscox T., Jost B.H., Billington S.J., Songer J.G., McClane B.A., Titball R.W., Rood J.I., Melville S.B., Paulsen I.T.
Genome Res. 16:1031-1040(2006) [PubMed: 16825665] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"Structural and mechanistic insight into the basis of mucopolysaccharidosis IIIB."
Ficko-Blean E., Stubbs K.A., Nemirovsky O., Vocadlo D.J., Boraston A.B.
Proc. Natl. Acad. Sci. U.S.A. 105:6560-6565(2008) [PubMed: 18443291] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 26-916 IN COMPLEX WITH CALCIUM AND N-ACETYL-D-GLUCOSAMINE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000246 Genomic DNA. Translation: ABG84150.1.
RefSeqYP_695309.1. NC_008261.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2VC9X-ray2.36A26-916[»]
2VCAX-ray2.05A26-916[»]
2VCBX-ray2.20A26-916[»]
2VCCX-ray2.00A26-916[»]
ProteinModelPortalQ0TST1.
SMRQ0TST1. Positions 26-911.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0TST1.

Protein family/group databases

CAZyCBM32. Carbohydrate-Binding Module Family 32.
GH89. Glycoside Hydrolase Family 89.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4203371.
GenomeReviewsGene locus CPF_0859 in contig CP000246_GR.
KEGGcpf:CPF_0859.
PATRIC19484016. VBICloPer106549_0830.
TIGRCPF_0859.

Phylogenomic databases

eggNOGNOG86381.
HOGENOMHBG428593.
OMATVLDMTS.
ProtClustDBCLSK899259.

Family and domain databases

InterProIPR000421. Coagulation_fac_5/8-C_type_dom.
IPR011490. Extracell_matric-bd_Ebh.
IPR003961. Fibronectin_type3.
IPR008979. Galactose-bd-like.
IPR013783. Ig-like_fold.
IPR007781. NAGLU.
IPR024732. NAGLU_C.
IPR024240. NAGLU_N.
IPR024733. NAGLU_tim-barrel.
[Graphical view]
Gene3DG3DSA:2.60.40.10. Ig-like_fold. 1 hit.
PANTHERPTHR12872. NAGLU. 1 hit.
PfamPF00754. F5_F8_type_C. 4 hits.
PF07554. FIVAR. 2 hits.
PF00041. fn3. 1 hit.
PF05089. NAGLU. 1 hit.
PF12972. NAGLU_C. 1 hit.
PF12971. NAGLU_N. 1 hit.
[Graphical view]
SMARTSM00060. FN3. 1 hit.
[Graphical view]
SUPFAMSSF49265. FN_III-like. 1 hit.
SSF49785. Gal_bind_like. 6 hits.
PROSITEPS50022. FA58C_3. 4 hits.
PS50853. FN3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ0TST1_CLOP1
AccessionPrimary (citable) accession number: Q0TST1
Entry history
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: December 14, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info