Q0TSP9 (EUTC_CLOP1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ethanolamine ammonia-lyase light chain
EC=4.3.1.7

Alternative name(s):
Ethanolamine ammonia-lyase small subunit

Gene names

Name:	eutC
Ordered Locus Names:	CPF_0892

Organism

Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A) [Complete proteome] [HAMAP]

Taxonomic identifier

195103 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	295 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Ethanolamine = acetaldehyde + NH3. HAMAP MF_00601
Cofactor	Adenosylcobalamin By similarity. HAMAP MF_00601
Pathway	Amine and polyamine degradation; ethanolamine degradation. HAMAP MF_00601
Subunit structure	Heterodimer of a small and a large subunit By similarity.
Sequence similarities	Belongs to the eutC family.

Ontologies

Keywords
Ligand	Cobalamin Cobalt
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular amino acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	cobalamin binding Inferred from electronic annotation. Source: UniProtKB-KW ethanolamine ammonia-lyase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 295	295	Ethanolamine ammonia-lyase light chain HAMAP MF_00601		PRO_1000025852

Sequences

	Sequence		Length	Mass (Da)
	Q0TSP9 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 155C2C662D362E69	FASTA	295	32,309
	10 20 30 40 50 60 MNEKDLKLMV EQLVSQMVGQ VDMQSVEKVV KEVSKNQSQV ESDEFIPDIT EIDIKKQLLV 70 80 90 100 110 120 DNPADREAYL EMKAKTPARL GSGRAGARYK TITALRMRAD HAAAQDSVFS DVSEEFIKKN 130 140 150 160 170 180 NFIPVKTMCT DKDEYVTRPD LGRRFSPETT EIIKEKCDKN PKVQIMVGDG LSSAAIEANV 190 200 210 220 230 240 EDILPSIEQG LKMYGLNVGP ILFVKYCRVP AMDAVGEATG ADVVCLLVGE RPGLVTAESM 250 260 270 280 290 SAYIAYKPKV GMPEAKRTVI SNIHKGGTTA VEAGAHIAEL IKTMLDKKAS GIDLK

References

[1]

"Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens." Myers G.S.A., Rasko D.A., Cheung J.K., Ravel J., Seshadri R., DeBoy R.T., Ren Q., Varga J., Awad M.M., Brinkac L.M., Daugherty S.C., Haft D.H., Dodson R.J., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A., Khouri H. , Dimitrov G.I., Watkins K.L., Mulligan S., Benton J., Radune D., Fisher D.J., Atkins H.S., Hiscox T., Jost B.H., Billington S.J., Songer J.G., McClane B.A., Titball R.W., Rood J.I., Melville S.B., Paulsen I.T. Genome Res. 16:1031-1040(2006) [PubMed: 16825665] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13124 / NCTC 8237 / Type A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000246 Genomic DNA. Translation: ABG82727.1.
RefSeq	YP_695341.1. NC_008261.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q0TSP9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4202813.
GenomeReviews	Gene locus CPF_0892 in contig CP000246_GR.
KEGG	cpf:CPF_0892.
PATRIC	19484082. VBICloPer106549_0863.
TIGR	CPF_0892.
Phylogenomic databases
eggNOG	COG4302.
HOGENOM	HBG363176.
OMA	IHKGGTP.
ProtClustDB	PRK05465.
Enzyme and pathway databases
BioCyc	CPER195103:CPF_0892-MONOMER.
Family and domain databases
HAMAP	MF_00601. EutC. [Tree]
InterPro	IPR009246. EutC. [Graphical view]
KO	K03736.
Pfam	PF05985. EutC. 1 hit. [Graphical view]
PIRSF	PIRSF018982. EutC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

EUTC_CLOP1

Accession

Primary (citable) accession number: Q0TSP9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 5, 2006
Last modified:	January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program