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Protein
Submitted name:

Sialidase

Gene

nanH

Organism
Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. exo-alpha-(2->3)-sialidase activity Source: UniProtKB-EC
  2. exo-alpha-(2->6)-sialidase activity Source: UniProtKB-EC
  3. exo-alpha-(2->8)-sialidase activity Source: UniProtKB-EC

GO - Biological processi

  1. pathogenesis Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Enzyme and pathway databases

BioCyciCPER195103:GHAW-1003-MONOMER.

Protein family/group databases

CAZyiGH33. Glycoside Hydrolase Family 33.

Names & Taxonomyi

Protein namesi
Submitted name:
SialidaseImported (EC:3.2.1.18Imported)
Gene namesi
Name:nanHImported
Ordered Locus Names:CPF_0985Imported
OrganismiClostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A)Imported
Taxonomic identifieri195103 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000001823: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi195103.CPF_0985.

Structurei

3D structure databases

ProteinModelPortaliQ0TSF8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG4409.
HOGENOMiHOG000119872.
KOiK01186.
OMAiYEANGNI.
OrthoDBiEOG67DPK3.

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
InterProiIPR026856. Sialidase_fam.
IPR008377. Sialidase_trypan.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PTHR10628:SF5. PTHR10628:SF5. 1 hit.
PRINTSiPR01803. TCSIALIDASE.
SUPFAMiSSF50939. SSF50939. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0TSF8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MYNKNNTFEK NLDISHKPEP LILFNKDNNI WNSKYFRIPN IQLLNDGTIL
60 70 80 90 100
TFSDIRYNGP DDHAYIDIAS ARSTDFGKTW SYDIAMKNNR IDSTYSRVMD
110 120 130 140 150
STTVITNTGR IILIAGSWNT NGNWAMTTST RRSDWSVQMI YSDDNGLTWS
160 170 180 190 200
NKIDLTKDSS KVKNQPSNTI GWLGGVGSGI VMDDGTIVMP AQISLRENNE
210 220 230 240 250
NNYYSLIIYS KDNGETWTMG NKVPNSNTSE NMVIELDGAL IMSTRYDYSG
260 270 280 290 300
YRAAYISHDL GTTWEIYEPL NGKVLTGKGS GCQGSFIKAT TSNGHRIGLI
310 320 330 340 350
SAPKNTKGEY IRDNIAVYMI DFDDLSKGVQ EICIPYPEDG NKLGGGYSCL
360 370 380
SFKNGHLGIV YEANGNIEYQ DLTPYYSLIN KQ
Length:382
Mass (Da):42,803
Last modified:September 5, 2006 - v1
Checksum:iFCE9468348668541
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000246 Genomic DNA. Translation: ABG84018.1.
RefSeqiWP_011590492.1. NC_008261.1.
YP_695432.1. NC_008261.1.

Genome annotation databases

EnsemblBacteriaiABG84018; ABG84018; CPF_0985.
GeneIDi4201816.
KEGGicpf:CPF_0985.
PATRICi19484264. VBICloPer106549_0952.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000246 Genomic DNA. Translation: ABG84018.1.
RefSeqiWP_011590492.1. NC_008261.1.
YP_695432.1. NC_008261.1.

3D structure databases

ProteinModelPortaliQ0TSF8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi195103.CPF_0985.

Protein family/group databases

CAZyiGH33. Glycoside Hydrolase Family 33.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG84018; ABG84018; CPF_0985.
GeneIDi4201816.
KEGGicpf:CPF_0985.
PATRICi19484264. VBICloPer106549_0952.

Phylogenomic databases

eggNOGiCOG4409.
HOGENOMiHOG000119872.
KOiK01186.
OMAiYEANGNI.
OrthoDBiEOG67DPK3.

Enzyme and pathway databases

BioCyciCPER195103:GHAW-1003-MONOMER.

Family and domain databases

Gene3Di2.120.10.10. 1 hit.
InterProiIPR026856. Sialidase_fam.
IPR008377. Sialidase_trypan.
IPR011040. Sialidases.
[Graphical view]
PANTHERiPTHR10628. PTHR10628. 1 hit.
PTHR10628:SF5. PTHR10628:SF5. 1 hit.
PRINTSiPR01803. TCSIALIDASE.
SUPFAMiSSF50939. SSF50939. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13124 / NCTC 8237 / Type AImported.

Entry informationi

Entry nameiQ0TSF8_CLOP1
AccessioniPrimary (citable) accession number: Q0TSF8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: February 4, 2015
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.