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Q0TRE4 (CAPPA_CLOP1) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppcA
Ordered Locus Names:CPF_1350
OrganismClostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A) [Complete proteome] [HAMAP]
Taxonomic identifier195103 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length537 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_01904

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_01904

Cofactor

Magnesium By similarity. HAMAP-Rule MF_01904

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_01904

Sequence similarities

Belongs to the PEPCase type 2 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 537537Phosphoenolpyruvate carboxylase HAMAP-Rule MF_01904
PRO_0000309594

Sequences

Sequence LengthMass (Da)Tools
Q0TRE4 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: CF43D5B22E28014C

FASTA53760,393
        10         20         30         40         50         60 
MKIPCSMMTQ HPDNVETYIS IQQEPAEAIK GLTPQDKGGL GIEEVMIDFE GKLTPYHQTS 

        70         80         90        100        110        120 
QIALGLISNG IIPGKDVRVT PRIPNANKES VFRQLMSIMS IIETNVQSKE LTGIPAISEV 

       130        140        150        160        170        180 
VVPMIETGKE ISEFQDRVNS VVDMGNKNYK TKLDLNSVRI IPLVEDVPAL ANIDRILDEH 

       190        200        210        220        230        240 
YEIEKSKGHV LKDLRIMIAR SDTAMSYGLI SGVLSVLMAV DGAYKWGEKH GVTISPILGC 

       250        260        270        280        290        300 
GSLPFRGHFS EENIDEILAT YSGIKTFTFQ SALRYDHGEE ATKHAVNELK AKIAESKPRN 

       310        320        330        340        350        360 
FSEEDKDLMK EFIGICSKHY LQTFLKVIDT VSFVSDFIPK NRDRLTKAKT GLEYNREVAN 

       370        380        390        400        410        420 
LDNVADLVKD EVLKQEILSI DNSKEYAVPR AISFTGAMYT LGMPPELMGM GRALNEIKTK 

       430        440        450        460        470        480 
YGQEGIDKLL EIYPILRKDL AFAARFANGG VSKKIIDEEA RQEYKEDMKY VNEILNLGLD 

       490        500        510        520        530 
YDFLNENEFY HTLLKTTKPI IMHLMGLEEN VMRNSTEELK ILNEWIVRMG KVRGSIG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000246 Genomic DNA. Translation: ABG83743.1.
RefSeqYP_695796.1. NC_008261.1.

3D structure databases

ProteinModelPortalQ0TRE4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING195103.CPF_1350.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABG83743; ABG83743; CPF_1350.
GeneID4202414.
KEGGcpf:CPF_1350.
PATRIC19484972. VBICloPer106549_1306.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1892.
HOGENOMHOG000009826.
KOK01595.
OMAPRAIKFT.
OrthoDBEOG6WDSG0.
ProtClustDBPRK13655.

Enzyme and pathway databases

BioCycCPER195103:GHAW-1368-MONOMER.

Family and domain databases

Gene3D3.20.20.60. 1 hit.
HAMAPMF_01904. PEPcase_type2.
InterProIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFPIRSF006677. UCP006677. 1 hit.
SUPFAMSSF51621. SSF51621. 1 hit.
TIGRFAMsTIGR02751. PEPCase_arch. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCAPPA_CLOP1
AccessionPrimary (citable) accession number: Q0TRE4
Entry history
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: September 5, 2006
Last modified: February 19, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families