Q0TNJ3 (Q0TNJ3_CLOP1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Selenide, water dikinase HAMAP MF_00625
EC=2.7.9.3 HAMAP MF_00625

Alternative name(s):
Selenium donor protein HAMAP MF_00625
Selenophosphate synthase HAMAP MF_00625

Gene names

Name:	selD HAMAP MF_00625 EMBL ABG83198.1
Ordered Locus Names:	CPF_2374

Organism

Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A) [Complete proteome] [HAMAP]

Taxonomic identifier

195103 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Synthesizes selenophosphate from selenide and ATP By similarity. HAMAP MF_00625 SAAS SAAS023061
Catalytic activity	ATP + selenide + H2O = AMP + selenophosphate + phosphate. HAMAP MF_00625 SAAS SAAS023061
Cofactor	Magnesium By similarity. HAMAP MF_00625 SAAS SAAS023061
Sequence similarities	Belongs to the selenophosphate synthase 1 family. Class I subfamily. HAMAP MF_00625

Ontologies

Keywords
Coding sequence diversity	Selenocysteine EMBL ABG83198.1
Ligand	ATP-binding HAMAP MF_00625 SAAS SAAS023061 Magnesium HAMAP MF_00625 SAAS SAAS023061 Nucleotide-binding Selenium HAMAP MF_00625 SAAS SAAS023061 EMBL ABG83198.1
Molecular function	Kinase HAMAP MF_00625 SAAS SAAS023061 EMBL ABG83198.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP selenide, water dikinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	226 – 232	7	ATP By similarity HAMAP MF_00625
Sites
	Active site	15	1	By similarity HAMAP MF_00625
	Site	18	1	Important for catalytic activity By similarity HAMAP MF_00625
Amino acid modifications
	Non-standard residue	15	1	Selenocysteine EMBL ABG83198.1

Sequences

	Sequence		Length	Mass (Da)
	Q0TNJ3 [UniParc]. Last modified February 26, 2008. Version 2. Checksum: 98D07CB18FC9A9C1	FASTA	343	37,485
	10 20 30 40 50 60 MIEKRLTELS KTSGUAAKIG PGALSEILSK LPKMNDKNLI VGIDTSDDAA VYKLNDEMAT 70 80 90 100 110 120 IQTLDFFTPI VDDPYTFGQI AAANSLSDVY AMGGKPIVAL NIVCFPNCLN MNILGEILRG 130 140 150 160 170 180 GADKVLEAGA VIVGGHTVQD DEPKYGLSVT GIVHPDKVLK NYGSETGDIL ILTKPIGLGI 190 200 210 220 230 240 INTAIKAKIA SKEAYEKAVK VMAYLNKYAG EIITDYNITS CTDITGFSLI GHAYEMAEPS 250 260 270 280 290 300 KKTFRIFKDA IPFIKEAKEY ASMGLIPAGC YENKRYLEGK YLLNNVESWM EDILFDPQTS 310 320 330 340 GGLLISCKEK DYIDILTRLE KLEVESAVIG RVEDFNDAYI VVE

References

[1]

"Skewed genomic variability in strains of the toxigenic bacterial pathogen, Clostridium perfringens." Myers G.S.A., Rasko D.A., Cheung J.K., Ravel J., Seshadri R., DeBoy R.T., Ren Q., Varga J., Awad M.M., Brinkac L.M., Daugherty S.C., Haft D.H., Dodson R.J., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A., Khouri H. , Dimitrov G.I., Watkins K.L., Mulligan S., Benton J., Radune D., Fisher D.J., Atkins H.S., Hiscox T., Jost B.H., Billington S.J., Songer J.G., McClane B.A., Titball R.W., Rood J.I., Melville S.B., Paulsen I.T. Genome Res. 16:1031-1040(2006) [PubMed: 16825665] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000246 Genomic DNA. Translation: ABG83198.1.
RefSeq	YP_696797.1. NC_008261.1.
3D structure databases
ProteinModelPortal	Q0TNJ3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0TNJ3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4203499.
GenomeReviews	Gene locus CPF_2374 in contig CP000246_GR.
KEGG	cpf:CPF_2374.
PATRIC	19487000. VBICloPer106549_2313.
TIGR	CPF_2374.
Phylogenomic databases
eggNOG	COG0709.
HOGENOM	HBG383791.
OMA	AGXAAKL.
ProtClustDB	CLSK2779191.
Family and domain databases
HAMAP	MF_00625. SelD. [Tree]
InterPro	IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR016188. PurM_N-like. IPR004536. SelD. IPR023061. SelD_I. [Graphical view]
KO	K01008.
Pfam	PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view]
PIRSF	PIRSF036407. Selenphspht_syn. 1 hit.
SUPFAM	SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit.
TIGRFAMs	TIGR00476. SelD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q0TNJ3_CLOP1

Accession

Primary (citable) accession number: Q0TNJ3

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2006
Last sequence update:	February 26, 2008
Last modified:	December 14, 2011
This is version 41 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)