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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei291 – 2911Proton donorUniRule annotation
Active sitei312 – 3121UniRule annotation
Active sitei426 – 4261UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCPER195103:GHAW-2566-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:CPF_2549
OrganismiClostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A)
Taxonomic identifieri195103 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000001823 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 450450Glucose-6-phosphate isomerasePRO_1000013958Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi195103.CPF_2549.

Structurei

3D structure databases

ProteinModelPortaliQ0TN51.
SMRiQ0TN51. Positions 8-449.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiSTQQMFL.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0TN51-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKGLVVDLS KAAPYLKSHE VAYMQETINQ AHNKLHNGTG AGNDFLGWVD
60 70 80 90 100
LPVNYDKDEF ARIKEAAKKI QSDSDVLVVI GIGGSYLGAR AAIEMLTNNF
110 120 130 140 150
YNSMSKDKRK TPAIFYAGNN ISSSYMADLL KAIDGLDVSL NVISKSGTTT
160 170 180 190 200
EPAIAFRILK DYMEKKYGKE EAKKRIYATT DAKKGALKTL ADAEGYETFV
210 220 230 240 250
IPDDVGGRFS VLTAVGLLPI AAAGINIDEM MEGAADAREE YANPSLADNE
260 270 280 290 300
CYKYAAARNA LYNKGKAIEI LVNYEPSVHY FNEWWKQLYG ESEGKDNKGL
310 320 330 340 350
FPAAVDFSTD LHSMGQYIQE GRRDIFETVI NVGSPREEIV IEANDENIDG
360 370 380 390 400
LNFLAGKTMD YVNKQAFRGT LLAHNDGEVP NVVVNVPELT PYYFGRLVYF
410 420 430 440 450
FEKACGISGY VLGINPFDQP GVEAYKKNMF ALLGKPGFED LKAELEERLK
Length:450
Mass (Da):49,771
Last modified:September 5, 2006 - v1
Checksum:i2DCBE5726DB52218
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000246 Genomic DNA. Translation: ABG82971.1.
RefSeqiWP_003462349.1. NC_008261.1.
YP_696939.1. NC_008261.1.

Genome annotation databases

EnsemblBacteriaiABG82971; ABG82971; CPF_2549.
GeneIDi990620.
KEGGicpf:CPF_2549.
PATRICi19487348. VBICloPer106549_2452.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000246 Genomic DNA. Translation: ABG82971.1.
RefSeqiWP_003462349.1. NC_008261.1.
YP_696939.1. NC_008261.1.

3D structure databases

ProteinModelPortaliQ0TN51.
SMRiQ0TN51. Positions 8-449.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi195103.CPF_2549.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG82971; ABG82971; CPF_2549.
GeneIDi990620.
KEGGicpf:CPF_2549.
PATRICi19487348. VBICloPer106549_2452.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiSTQQMFL.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.
BioCyciCPER195103:GHAW-2566-MONOMER.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 13124 / NCTC 8237 / Type A.

Entry informationi

Entry nameiG6PI_CLOP1
AccessioniPrimary (citable) accession number: Q0TN51
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 5, 2006
Last modified: May 27, 2015
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.