ID   COMB_CLOP1              Reviewed;         247 AA.
AC   Q0TM95;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   05-MAY-2009, entry version 17.
DE   RecName: Full=Probable 2-phosphosulfolactate phosphatase;
DE            EC=3.1.3.71;
GN   Name=comB; OrderedLocusNames=CPF_2881;
OS   Clostridium perfringens (strain ATCC 13124 / NCTC 8237 / Type A).
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=195103;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16825665; DOI=10.1101/gr.5238106;
RA   Myers G.S.A., Rasko D.A., Cheung J.K., Ravel J., Seshadri R.,
RA   DeBoy R.T., Ren Q., Varga J., Awad M.M., Brinkac L.M., Daugherty S.C.,
RA   Haft D.H., Dodson R.J., Madupu R., Nelson W.C., Rosovitz M.J.,
RA   Sullivan S.A., Khouri H., Dimitrov G.I., Watkins K.L., Mulligan S.,
RA   Benton J., Radune D., Fisher D.J., Atkins H.S., Hiscox T., Jost B.H.,
RA   Billington S.J., Songer J.G., McClane B.A., Titball R.W., Rood J.I.,
RA   Melville S.B., Paulsen I.T.;
RT   "Skewed genomic variability in strains of the toxigenic bacterial
RT   pathogen, Clostridium perfringens.";
RL   Genome Res. 16:1031-1040(2006).
CC   -!- CATALYTIC ACTIVITY: (2R)-2-phospho-3-sulfolactate + H(2)O = (2R)-
CC       3-sulfolactate + phosphate.
CC   -!- COFACTOR: Magnesium (By similarity).
CC   -!- SIMILARITY: Belongs to the comB family.
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DR   EMBL; CP000246; ABG85008.1; -; Genomic_DNA.
DR   RefSeq; YP_697245.1; -.
DR   GeneID; 4203455; -.
DR   GenomeReviews; CP000246_GR; CPF_2881.
DR   KEGG; cpf:CPF_2881; -.
DR   TIGR; CPF_2881; -.
DR   HOGENOM; Q0TM95; -.
DR   OMA; Q0TM95; DFICSGY.
DR   GO; GO:0050532; F:2-phosphosulfolactate phosphatase activity; IEA:HAMAP.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP.
DR   GO; GO:0019295; P:coenzyme M biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_00490; -; 1.
DR   InterPro; IPR005238; 2-PSlactate_phosphatase.
DR   Gene3D; G3DSA:3.90.1560.10; 2-PSlactate_phosphatase; 1.
DR   Pfam; PF04029; 2-ph_phosp; 1.
DR   TIGRFAMs; TIGR00298; 2-ph_phosphatase; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase; Magnesium.
FT   CHAIN         1    247       Probable 2-phosphosulfolactate
FT                                phosphatase.
FT                                /FTId=PRO_1000014463.
SQ   SEQUENCE   247 AA;  27221 MW;  CDD05C763E9FC598 CRC64;
     MKIDVIISAD YIDSEALKGK IAVVIDMLRA TSVITTALYN GAKKVIPVVS VEEAFEKAKE
     LKSLGEEVLL GGERKALKID GFDFSNSPLE YKREIVEGKN VIMSTTNGTR ALNLCSKADK
     VIVASVLNGQ AVAKYLENEE KEIVFVNSGT NGEFSSDDFM CAGYIISELC KNKEAELTDI
     AKTAKYVYES SEGIEEFIKD AKHYNILKNL GLEEDLKYCS TKNLIDLVFE FKNGEIKTVE
     SGVKVTI
//