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Q0TKD6 (ALLA_ECOL5) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ureidoglycolate hydrolase
EC=3.5.3.19
Gene names
Name:allA
Ordered Locus Names:ECP_0566
OrganismEscherichia coli O6:K15:H31 (strain 536 / UPEC) [Complete proteome] [HAMAP]
Taxonomic identifier362663 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length160 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the anaerobic utilization of allantoin. Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate By similarity. HAMAP MF_00616

Catalytic activity

(S)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2. HAMAP MF_00616

Pathway

Nitrogen metabolism; (S)-allantoin degradation; glyoxylate from (S)-ureidoglycolate: step 1/1. HAMAP MF_00616

Subunit structure

Homodimer By similarity. HAMAP MF_00616

Sequence similarities

Belongs to the ureidoglycolate hydrolase family.

Ontologies

Keywords
   Biological processPurine metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processallantoin catabolic process

Inferred from electronic annotation. Source: InterPro

purine base metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionureidoglycolate hydrolase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 160160Ureidoglycolate hydrolase HAMAP MF_00616
PRO_1000061354

Sequences

Sequence LengthMass (Da)Tools
Q0TKD6 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: EFB868930FE92334

FASTA16018,223
        10         20         30         40         50         60 
MKLQVLPLSQ EAFSAYGDVI ETQKRDFFHI NNGLVERYHD LALVEILEQD RTLISINRAQ 

        70         80         90        100        110        120 
PANLPLTIHE LERHPLGTQA FIPMKGEVFV VVVALGDDKP DLSTLRAFIT NGEQGVNYHR 

       130        140        150        160 
NVWHHPLFAW QRVTDFLTID RGGSDNCDVE SIPEQELCFA

« Hide

References

[1]"Role of pathogenicity island-associated integrases in the genome plasticity of uropathogenic Escherichia coli strain 536."
Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U., Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J.
Mol. Microbiol. 61:584-595(2006) [PubMed: 16879640] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 536 / UPEC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000247 Genomic DNA. Translation: ABG68595.1.
RefSeqYP_668494.1. NC_008253.1.

3D structure databases

ProteinModelPortalQ0TKD6.
SMRQ0TKD6. Positions 1-160.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0TKD6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000048551; EBESCP00000046740; EBESCG00000047601.
GeneID4191702.
GenomeReviewsGene locus ECP_0566 in contig CP000247_GR.
KEGGecp:ECP_0566.
PATRIC18191791. VBIEscCol77757_0569.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3194.
GeneTreeEBGT00050000010044.
HOGENOMHBG289179.
OMASQAFIPM.
PhylomeDBQ0TKD6.
ProtClustDBPRK03606.

Enzyme and pathway databases

BioCycECOL362663:ECP_0566-MONOMER.

Family and domain databases

HAMAPMF_00616. Ureidogly_hydro.
[Tree]
InterProIPR011051. Cupin_RmlC_type.
IPR007247. Ureidogly_hydro.
IPR023525. Ureidogly_hydro_bac.
IPR024060. Ureidoglycolate_hydrolase_dom.
[Graphical view]
Gene3DG3DSA:2.60.120.480. G3DSA:2.60.120.480. 1 hit.
KOK01483.
PANTHERPTHR21221. Ureidogly_hydro. 1 hit.
PfamPF04115. Ureidogly_hydro. 1 hit.
[Graphical view]
PIRSFPIRSF017306. Ureidogly_hydro. 1 hit.
SUPFAMSSF51182. RmlC_like_cupin. 1 hit.
ProtoNetSearch...

Entry information

Entry nameALLA_ECOL5
AccessionPrimary (citable) accession number: Q0TKD6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: September 5, 2006
Last modified: January 25, 2012
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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