Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase

Gene

citG

Organism
Escherichia coli O6:K15:H31 (strain 536 / UPEC)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A, the precursor of the prosthetic group of the holo-acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA.UniRule annotation

Catalytic activityi

ATP + 3'-dephospho-CoA = 2'-(5-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA + adenine.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciECOL362663:GIY5-645-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthaseUniRule annotation (EC:2.4.2.52UniRule annotation)
Short name:
2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthaseUniRule annotation
Gene namesi
Name:citGUniRule annotation
Ordered Locus Names:ECP_0644
OrganismiEscherichia coli O6:K15:H31 (strain 536 / UPEC)
Taxonomic identifieri362663 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2922922-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthasePRO_0000255400Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi362663.ECP_0644.

Structurei

3D structure databases

ProteinModelPortaliQ0TK59.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CitG/MdcB family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108K6F. Bacteria.
COG1767. LUCA.
HOGENOMiHOG000258582.
KOiK05966.
OMAiIHRGGIK.

Family and domain databases

HAMAPiMF_00397. CitG. 1 hit.
InterProiIPR002736. CitG.
IPR017551. TriPribosyl-deP-CoA_syn_CitG.
[Graphical view]
PfamiPF01874. CitG. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03125. citrate_citG. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0TK59-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSMPATSTKT TKLATSLIDE YALLGWRAML TEVNLSPKPG LVDRINCGAH
60 70 80 90 100
KDMALEDFHR SALAIQGWLP RFIEFGACSA EMAPEAVLNG LRPIGMACEG
110 120 130 140 150
DMFRATAGVN THKGSIFSLG LLCAAIGRLL QLNQPVTPTT VCSTAASFCR
160 170 180 190 200
GLTDRELRTN NARLTAGQRL YQQLGLTGAR GEAEAGYPLV INHALPHYLT
210 220 230 240 250
LLDQGLDPEL ALLDTLLLLM ATNGDTNVAS RGGEGGLRWL QREAQTLLQK
260 270 280 290
GGIRTPADLD YLRQFDRECI ERNLSPGGSA DLLILTWFLA QI
Length:292
Mass (Da):31,621
Last modified:September 5, 2006 - v1
Checksum:i72BFC40249E35AF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000247 Genomic DNA. Translation: ABG68672.1.
RefSeqiWP_000062470.1. NC_008253.1.

Genome annotation databases

EnsemblBacteriaiABG68672; ABG68672; ECP_0644.
KEGGiecp:ECP_0644.
PATRICi18191951. VBIEscCol77757_0648.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000247 Genomic DNA. Translation: ABG68672.1.
RefSeqiWP_000062470.1. NC_008253.1.

3D structure databases

ProteinModelPortaliQ0TK59.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi362663.ECP_0644.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG68672; ABG68672; ECP_0644.
KEGGiecp:ECP_0644.
PATRICi18191951. VBIEscCol77757_0648.

Phylogenomic databases

eggNOGiENOG4108K6F. Bacteria.
COG1767. LUCA.
HOGENOMiHOG000258582.
KOiK05966.
OMAiIHRGGIK.

Enzyme and pathway databases

BioCyciECOL362663:GIY5-645-MONOMER.

Family and domain databases

HAMAPiMF_00397. CitG. 1 hit.
InterProiIPR002736. CitG.
IPR017551. TriPribosyl-deP-CoA_syn_CitG.
[Graphical view]
PfamiPF01874. CitG. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03125. citrate_citG. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCITG_ECOL5
AccessioniPrimary (citable) accession number: Q0TK59
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: September 5, 2006
Last modified: September 7, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.