Reviewed, UniProtKB/Swiss-Prot Q0TK58 (CITX_ECOL5)

Names and origin

Protein names

Recommended name:
    Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
    EC=2.7.7.61
Alternative name(s):
    Holo-ACP synthase
    Holo-citrate lyase synthase
    Apo-ACP nucleodityltransferase

Gene names

Name:	citX
Ordered Locus Names:	ECP_0645

Organism

Escherichia coli O6:K15:H31 (strain 536 / UPEC) [Complete proteome] [HAMAP]

Taxonomic identifier

362663 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	183 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein By similarity.
Catalytic activity	2'-(5-triphosphoribosyl)-3'-dephospho-CoA + citrate lyase apo-[acyl-carrier-protein] = citrate lyase holo-[acyl-carrier-protein] + diphosphate. HAMAP MF_00398
Sequence similarities	Belongs to the citX family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	holo-citrate lyase synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 183	183	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase HAMAP MF_00398		PRO_1000049602

Sequences

	Sequence		Length	Mass (Da)
	Q0TK58-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 353DAB41BC78CBCE	FASTA	183	20,228
	10 20 30 40 50 60 MHLLPELASH HAVSIPELLV SRDERQARQH AWLKRHPVPL VSFTVVAPGP IKDSEVTRRI 70 80 90 100 110 120 FNHGVTALRA LAAKQGWQIQ EQAALVSASG PEGMLSIAAP ARDLKLATIE LEHSHPLGRL 130 140 150 160 170 180 WDIDVLTPEG DILSRRDYSL PPRRCLLCEQ SAAVCARGKT HQLTDLLNRM EALLNDVDAC NVN

References

[1]

"Role of pathogenicity island-associated integrases in the genome plasticity of uropathogenic Escherichia coli strain 536." Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U., Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J. Mol. Microbiol. 61:584-595(2006) [PubMed: 16879640] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000247 Genomic DNA. Translation: ABG68673.1.
RefSeq	YP_668572.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4188202.
GenomeReviews	Gene locus ECP_0645 in contig CP000247_GR.
KEGG	ecp:ECP_0645.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0TK58.
OMA	Q0TK58. TGYEYYL.
Enzyme and pathway databases
BioCyc	ECOL362663:ECP_0645-MON.
Family and domain databases
HAMAP	MF_00398. [Tree]
InterPro	IPR005551. CitX. [Graphical view]
Pfam	PF03802. CitX. 1 hit. [Graphical view]
TIGRFAMs	TIGR03124. ctirate_citX. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CITX_ECOL5

Accession

Primary (citable) accession number: Q0TK58

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 5, 2006
Last modified:	June 16, 2009
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)