Reviewed,
UniProtKB/Swiss-Prot Q0THR7 (UXAB_ECOL5)
Last modified
July 13, 2010.
Version 30.
History...
Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
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Names and originHide
| Protein names | Recommended name: Altronate oxidoreductase EC=1.1.1.58 Alternative name(s): Tagaturonate reductase Tagaturonate dehydrogenase | ||||
| Gene names |
| ||||
| Organism | Escherichia coli O6:K15:H31 (strain 536 / UPEC) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 362663 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia |
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Protein attributesHide
| Sequence length | 483 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
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General annotation (Comments)Hide
| Catalytic activity | D-altronate + NAD+ = D-tagaturonate + NADH. HAMAP MF_00670 |
| Pathway | Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00670 |
| Sequence similarities | Belongs to the mannitol dehydrogenase family. UxaB subfamily. |
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OntologiesHide
| Keywords | |
|---|---|
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | coenzyme binding Inferred from electronic annotation. Source: InterPro tagaturonate reductase activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
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Sequence annotation (Features)Hide
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 483 | 483 | Altronate oxidoreductase HAMAP MF_00670 | PRO_1000044703 | |||||
Regions | |||||||||
| Nucleotide binding | 18 – 29 | 12 | NAD By similarity | ||||||
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SequencesHide
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ReferencesHide
| [1] | "Role of pathogenicity island-associated integrases in the genome plasticity of uropathogenic Escherichia coli strain 536." Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U., Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J. Mol. Microbiol. 61:584-595(2006) [PubMed: 16879640] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
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Cross-referencesHide
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000247 Genomic DNA. Translation: ABG69512.1. |
| RefSeq | YP_669413.1. |
3D structure databases | |
| SMR | Q0THR7. Positions 4-482. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q0THR7. |
Genome annotation databases | |
| EnsemblBacteria | EBESCT00000046160; EBESCP00000044349; EBESCG00000045210. |
| GeneID | 4187930. |
| GenomeReviews | Gene locus ECP_1505 in contig CP000247_GR. |
| KEGG | ecp:ECP_1505. |
| NMPDR | fig|340197.3.peg.4284. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0246. |
| HOGENOM | HBG297101. |
| OMA | MTKYRTR. |
| PhylomeDB | Q0THR7. |
| ProtClustDB | PRK03643. |
Enzyme and pathway databases | |
| BioCyc | ECOL362663:ECP_1505-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00670. Altron_oxidoreduct. [Tree] |
| InterPro | IPR008927. 6-PGluconate_DH_C_like. IPR013328. DH_multihelical. IPR013118. Mannitol_DH_C. IPR013131. Mannitol_DH_N. IPR016040. NAD(P)-bd_dom. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit. |
| Pfam | PF01232. Mannitol_dh. 1 hit. PF08125. Mannitol_dh_C. 1 hit. [Graphical view] |
| SUPFAM | SSF48179. 6DGDH_C_like. 1 hit. |
| ProtoNet | Search... |
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Entry informationHide
| Entry name | UXAB_ECOL5 | ||||||||
| Accession | Primary (citable) accession number: Q0THR7 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
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Relevant documentsHide
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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