Reviewed, UniProtKB/Swiss-Prot Q0TFL0 (UBIG_ECOL5)

Names and origin

Protein names

Recommended name:
    3-demethylubiquinone-9 3-methyltransferase
    EC=2.1.1.64
Alternative name(s):
    3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase
      Short name=DHHB methyltransferase

Gene names

Name:	ubiG
Ordered Locus Names:	ECP_2275

Organism

Escherichia coli O6:K15:H31 (strain 536 / UPEC) [Complete proteome] [HAMAP]

Taxonomic identifier

362663 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	240 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9. HAMAP MF_00472
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_00472
Sequence similarities	Belongs to the methyltransferase superfamily. UbiG/COQ3 family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity Inferred from electronic annotation. Source: InterPro 3-demethylubiquinone-9 3-O-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 240	240	3-demethylubiquinone-9 3-methyltransferase HAMAP MF_00472		PRO_1000013899

Sequences

	Sequence		Length	Mass (Da)
	Q0TFL0-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 93F5364A1E1F911F	FASTA	240	26,573
	10 20 30 40 50 60 MNAEKSPVNH NVDHKEIAKF EAVASRWWDL EGEFKPLHRI NPLRLGYIAE RAGGLFGKKV 70 80 90 100 110 120 LDVGCGGGIL AESMAREGAT VTGLDMGFEP LQVAKLHALE SGIQVDYVQE TVEEHAAKHA 130 140 150 160 170 180 GQYDVVTCME MLEHVPDPQS VVRACAQLVK PGGDVFFSTL NRNGKSWLMA VVGAEYILRM 190 200 210 220 230 240 VPKGTHDVKK FIKPAELLGW VDQTSLKERH MTGLHYNPIT NTFKLGPGVD VNYMLHTQNK

References

[1]

"Role of pathogenicity island-associated integrases in the genome plasticity of uropathogenic Escherichia coli strain 536." Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U., Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J. Mol. Microbiol. 61:584-595(2006) [PubMed: 16879640] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000247 Genomic DNA. Translation: ABG70269.1.
RefSeq	YP_670170.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4191924.
GenomeReviews	Gene locus ECP_2275 in contig CP000247_GR.
KEGG	ecp:ECP_2275.
NMPDR	fig|340197.3.peg.297.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0TFL0.
OMA	Q0TFL0. PLRLGWI.
Enzyme and pathway databases
BioCyc	ECOL362663:ECP_2275-MON.
Family and domain databases
HAMAP	MF_00472. [Tree]
InterPro	IPR013216. Methyltransf_11. IPR010233. UbiG_MeTrfase. [Graphical view]
Pfam	PF08241. Methyltransf_11. 1 hit. [Graphical view]
TIGRFAMs	TIGR01983. UbiG. 1 hit.
ProtoNet	Search...

Entry information

Entry name

UBIG_ECOL5

Accession

Primary (citable) accession number: Q0TFL0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 5, 2006
Last modified:	June 16, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)