ID   SDHD1_ECOL5             Reviewed;         442 AA.
AC   Q0TF95;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   16-JUN-2009, entry version 21.
DE   RecName: Full=D-serine dehydratase 1;
DE            EC=4.3.1.18;
DE   AltName: Full=D-serine deaminase 1;
DE            Short=DSD 1;
GN   Name=dsdA1; OrderedLocusNames=ECP_2391;
OS   Escherichia coli O6:K15:H31 (strain 536 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=362663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16879640; DOI=10.1111/j.1365-2958.2006.05255.x;
RA   Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U.,
RA   Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J.;
RT   "Role of pathogenicity island-associated integrases in the genome
RT   plasticity of uropathogenic Escherichia coli strain 536.";
RL   Mol. Microbiol. 61:584-595(2006).
CC   -!- CATALYTIC ACTIVITY: D-serine = pyruvate + NH(3).
CC   -!- COFACTOR: Pyridoxal phosphate (By similarity).
CC   -!- SUBUNIT: Monomer (By similarity).
CC   -!- SIMILARITY: Belongs to the serine/threonine dehydratase family.
CC       DsdA subfamily.
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DR   EMBL; CP000247; ABG70384.1; -; Genomic_DNA.
DR   RefSeq; YP_670285.1; -.
DR   GeneID; 4189628; -.
DR   GenomeReviews; CP000247_GR; ECP_2391.
DR   KEGG; ecp:ECP_2391; -.
DR   NMPDR; fig|340197.3.peg.3902; -.
DR   HOGENOM; Q0TF95; -.
DR   OMA; Q0TF95; QLHGFSA.
DR   BioCyc; ECOL362663:ECP_2391-MON; -.
DR   GO; GO:0008721; F:D-serine ammonia-lyase activity; IEA:EC.
DR   GO; GO:0016836; F:hydro-lyase activity; IEA:HAMAP.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0046416; P:D-amino acid metabolic process; IEA:HAMAP.
DR   HAMAP; MF_01030; -; 1.
DR   InterPro; IPR011780; D_Ser_am_lyase.
DR   InterPro; IPR001926; PyrdxlP-dep_enz_bsu.
DR   InterPro; IPR000634; Ser/Thr_deHydtase_PyrdxlP-BS.
DR   PANTHER; PTHR10314:SF9; D_Ser_am_lyase; 1.
DR   Pfam; PF00291; PALP; 1.
DR   TIGRFAMs; TIGR02035; D_Ser_am_lyase; 1.
DR   PROSITE; PS00165; DEHYDRATASE_SER_THR; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Lyase; Pyridoxal phosphate.
FT   CHAIN         1    442       D-serine dehydratase 1.
FT                                /FTId=PRO_0000291729.
FT   MOD_RES     118    118       N6-(pyridoxal phosphate)lysine (By
FT                                similarity).
SQ   SEQUENCE   442 AA;  47859 MW;  91FEEC58F8200BD2 CRC64;
     MENAKMNSLI AQYPLVKDLV ALQETTWFNP GTTSLAEGLP YVGLTEQDVQ DAHARLSRFA
     PYLAKAFPET AATGGIIESE LVAIPAMQKR LEKEYHQPIA GQLLLKKDSH LPISGSIKAR
     GGIYEVLAHA EKLALEAGLL TLEDDYSKLL SPEFKQFFSQ YSIAVGSTGN LGLSIGIMSA
     RIGFKVTVHM SADARAWKKA KLRSHGVTVV EYEQDYGVAV EEGRKAAQSD PNCFFIDDEN
     SRTLFLGYSV AGQRLKAQFA QQGRIVNADN PLFVYLPCGV GGGPGGVAFG LKLAFGDHVH
     CFFAEPTHSP CMLLGVHTGL HDQISVQDIG IDNLTAADGL AVGRASGFVG RAMERLLDGF
     YTLSDQTMYD MLGWLAQEEG IRLEPSALAG MAGPQRVCAS VSYQQLHGFS AEQLRNATHL
     VWATGGGMVP EEEMNQYLAK GR
//