ID   UXAC_ECOL5              Reviewed;         470 AA.
AC   Q0TD14;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   16-JUN-2009, entry version 18.
DE   RecName: Full=Uronate isomerase;
DE            EC=5.3.1.12;
DE   AltName: Full=Glucuronate isomerase;
DE   AltName: Full=Uronic isomerase;
GN   Name=uxaC; OrderedLocusNames=ECP_3183;
OS   Escherichia coli O6:K15:H31 (strain 536 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=362663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16879640; DOI=10.1111/j.1365-2958.2006.05255.x;
RA   Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U.,
RA   Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J.;
RT   "Role of pathogenicity island-associated integrases in the genome
RT   plasticity of uropathogenic Escherichia coli strain 536.";
RL   Mol. Microbiol. 61:584-595(2006).
CC   -!- CATALYTIC ACTIVITY: D-glucuronate = D-fructuronate.
CC   -!- CATALYTIC ACTIVITY: D-galacturonate = D-tagaturonate.
CC   -!- PATHWAY: Carbohydrate metabolism; pentose and glucuronate
CC       interconversion.
CC   -!- SIMILARITY: Belongs to the uronate isomerase family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000247; ABG71165.1; -; Genomic_DNA.
DR   RefSeq; YP_671066.1; -.
DR   GeneID; 4188464; -.
DR   GenomeReviews; CP000247_GR; ECP_3183.
DR   KEGG; ecp:ECP_3183; -.
DR   HOGENOM; Q0TD14; -.
DR   OMA; Q0TD14; AWAKTVP.
DR   BioCyc; ECOL362663:ECP_3183-MON; -.
DR   GO; GO:0008880; F:glucuronate isomerase activity; IEA:HAMAP.
DR   GO; GO:0006064; P:glucuronate catabolic process; IEA:InterPro.
DR   HAMAP; MF_00675; -; 1.
DR   InterPro; IPR003766; UxaC.
DR   Pfam; PF02614; UxaC; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Isomerase.
FT   CHAIN         1    470       Uronate isomerase.
FT                                /FTId=PRO_1000044765.
SQ   SEQUENCE   470 AA;  53987 MW;  9E51AA7B88411281 CRC64;
     MTPFMTEDFL LDTEFARRLY HDYAKDQPIF DYHCHLPPQQ IAEDYRFKNL YDIWLKGDHY
     KWRAMRTNGV AERLCTGDAS DREKFDAWAA TVPHTIGNPL YHWTHLELRR PFGITGKLLS
     PSTADEIWNE CNELLAQDNF SARGIMQQMN VKMVGTTDDP IDSLEHHAEI AKDGSFTIKV
     LPSWRPDKAF NIEQATFNDY MAKLGEVSDT DIRRFADLQT ALTKRLDHFA AHGCKVSDHA
     LDVVMFAEAN EAELDSILAR RLAGETLSEH EVAQFKTAVL VFLGAEYARR GWVQQYHIGA
     LRNNNLRQFK LLGPDVGFDS INDRPMAEEL SKLLSKQNEE NLLPKTILYC LNPRDNEVLG
     TMIGNFQGEG MPGKMQFGSG WWFNDQKDGM ERQMTQLAQL GLLSRFVGML TDSRSFLSYT
     RHEYFRRILC QMIGRWVEAG EAPADINLLG EMVKNICFNN ARDYFAIELN
//