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Q0TD14 (UXAC_ECOL5) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Uronate isomerase
EC=5.3.1.12
Alternative name(s):
Glucuronate isomerase
Uronic isomerase
Gene names
Name:uxaC
Ordered Locus Names:ECP_3183
OrganismEscherichia coli O6:K15:H31 (strain 536 / UPEC) [Complete proteome] [HAMAP]
Taxonomic identifier362663 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length470 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucuronate = D-fructuronate. HAMAP MF_00675

D-galacturonate = D-tagaturonate. HAMAP MF_00675

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00675

Sequence similarities

Belongs to the uronate isomerase family.

Ontologies

Keywords
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglucuronate catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionglucuronate isomerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 470470Uronate isomerase HAMAP MF_00675
PRO_1000044765

Sequences

Sequence LengthMass (Da)Tools
Q0TD14 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 9E51AA7B88411281

FASTA47053,987
        10         20         30         40         50         60 
MTPFMTEDFL LDTEFARRLY HDYAKDQPIF DYHCHLPPQQ IAEDYRFKNL YDIWLKGDHY 

        70         80         90        100        110        120 
KWRAMRTNGV AERLCTGDAS DREKFDAWAA TVPHTIGNPL YHWTHLELRR PFGITGKLLS 

       130        140        150        160        170        180 
PSTADEIWNE CNELLAQDNF SARGIMQQMN VKMVGTTDDP IDSLEHHAEI AKDGSFTIKV 

       190        200        210        220        230        240 
LPSWRPDKAF NIEQATFNDY MAKLGEVSDT DIRRFADLQT ALTKRLDHFA AHGCKVSDHA 

       250        260        270        280        290        300 
LDVVMFAEAN EAELDSILAR RLAGETLSEH EVAQFKTAVL VFLGAEYARR GWVQQYHIGA 

       310        320        330        340        350        360 
LRNNNLRQFK LLGPDVGFDS INDRPMAEEL SKLLSKQNEE NLLPKTILYC LNPRDNEVLG 

       370        380        390        400        410        420 
TMIGNFQGEG MPGKMQFGSG WWFNDQKDGM ERQMTQLAQL GLLSRFVGML TDSRSFLSYT 

       430        440        450        460        470 
RHEYFRRILC QMIGRWVEAG EAPADINLLG EMVKNICFNN ARDYFAIELN

« Hide

References

[1]"Role of pathogenicity island-associated integrases in the genome plasticity of uropathogenic Escherichia coli strain 536."
Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U., Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J.
Mol. Microbiol. 61:584-595(2006) [PubMed: 16879640] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 536 / UPEC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000247 Genomic DNA. Translation: ABG71165.1.
RefSeqYP_671066.1. NC_008253.1.

3D structure databases

ProteinModelPortalQ0TD14.
SMRQ0TD14. Positions 4-468.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0TD14.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000049100; EBESCP00000047289; EBESCG00000048148.
GeneID4188464.
GenomeReviewsGene locus ECP_3183 in contig CP000247_GR.
KEGGecp:ECP_3183.
PATRIC18197210. VBIEscCol77757_3224.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1904.
GeneTreeEBGT00050000011224.
HOGENOMHBG297087.
OMAAWAKTVP.
PhylomeDBQ0TD14.
ProtClustDBPRK02925.

Enzyme and pathway databases

BioCycECOL362663:ECP_3183-MONOMER.

Family and domain databases

HAMAPMF_00675. UxaC.
[Tree]
InterProIPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
Gene3DG3DSA:1.10.2020.10. Uronate_isomerase_dom2. 1 hit.
KOK01812.
PfamPF02614. UxaC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUXAC_ECOL5
AccessionPrimary (citable) accession number: Q0TD14
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 5, 2006
Last modified: January 25, 2012
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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