Q0TCY2 (Q0TCY2_ECOL5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-hydroxy-3-oxopropionate reductase EMBL ABG71197.1
EC=1.1.1.60 EMBL ABG71197.1

Gene names

Ordered Locus Names:

ECP_3215

Organism

Escherichia coli O6:K15:H31 (strain 536 / UPEC) [Complete proteome] [HAMAP] EMBL ABG71197.1

Taxonomic identifier

362663 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	299 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL ABG71197.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glyoxylate metabolic process Inferred from electronic annotation. Source: InterPro pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro valine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-hydroxy-3-oxopropionate reductase activity Inferred from electronic annotation. Source: EC 3-hydroxyisobutyrate dehydrogenase activity Inferred from electronic annotation. Source: InterPro coenzyme binding Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro phosphogluconate dehydrogenase (decarboxylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q0TCY2 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: 08E65F785BC2B566	FASTA	299	31,019
	10 20 30 40 50 60 MIDMTMKVGF IGLGIMGKPM SKNLLKAGYS LVVADRNPEA IADVIAAGAE TASTAKAIAE 70 80 90 100 110 120 QCDVIITMLP NSPHVKEVAL GENGIIEGAK PGTVLIDMSS IAPLASREIS EALKAKGIDM 130 140 150 160 170 180 LDAPVSGGEP KAIDGTLSVM VGGDKAIFDK YYDLMKAMAG SVVHTGEIGA GNVTKLANQV 190 200 210 220 230 240 IVALNIAAMS EALTLATKAG VNPDLVYQAI RGGLAGSTVL DAKAPMVMDR NFKPGFRIDL 250 260 270 280 290 HIKDLANALD TSHGVGAQLP LTAAVMEMMQ ALRADGLGTA DHSALACYYE KLAKVEVTR

References

[1]

"Role of pathogenicity island-associated integrases in the genome plasticity of uropathogenic Escherichia coli strain 536." Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U., Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J. Mol. Microbiol. 61:584-595(2006) [PubMed: 16879640] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 536 EMBL ABG71197.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000247 Genomic DNA. Translation: ABG71197.1.
RefSeq	YP_671098.1. NC_008253.1.
3D structure databases
ProteinModelPortal	Q0TCY2.
SMR	Q0TCY2. Positions 6-299.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0TCY2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000049970; EBESCP00000048159; EBESCG00000049018.
GeneID	4188536.
GenomeReviews	Gene locus ECP_3215 in contig CP000247_GR.
KEGG	ecp:ECP_3215.
PATRIC	18197274. VBIEscCol77757_3256.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2084.
GeneTree	EBGT00050000009837.
HOGENOM	HBG729179.
OMA	WSRRRES.
PhylomeDB	Q0TCY2.
ProtClustDB	PRK11559.
Family and domain databases
InterPro	IPR002204. 3-OH-isobutyrate_DH-rel_CS. IPR015815. 3hydroxyacid_DH/Rdtase. IPR008927. 6-PGluconate_DH_C-like. IPR006115. 6PGDH_NADP-bd. IPR013328. DH_multihelical. IPR016040. NAD(P)-bd_dom. IPR006398. Tartro_sem_red. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KO	K00042.
PANTHER	PTHR22981. 3hydroxy_acid_DH. 1 hit.
Pfam	PF03446. NAD_binding_2. 1 hit. [Graphical view]
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMs	TIGR01505. Tartro_sem_red. 1 hit.
PROSITE	PS00895. 3_HYDROXYISOBUT_DH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q0TCY2_ECOL5

Accession

Primary (citable) accession number: Q0TCY2

Entry history

Integrated into UniProtKB/TrEMBL:	September 5, 2006
Last sequence update:	September 5, 2006
Last modified:	January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)