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Q0TAF9 (RHAB_ECOL5) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Rhamnulokinase
EC=2.7.1.5
Alternative name(s):
Rhamnulose kinase
Gene names
Name:rhaB
Ordered Locus Names:ECP_4114
OrganismEscherichia coli O6:K15:H31 (strain 536 / UPEC) [Complete proteome] [HAMAP]
Taxonomic identifier362663 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length489 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate. HAMAP MF_01535

Pathway

Carbohydrate degradation; L-rhamnose degradation; glycerone phosphate from L-rhamnose: step 2/3. HAMAP MF_01535

Subunit structure

Monomer By similarity. HAMAP MF_01535

Sequence similarities

Belongs to the rhamnulokinase family.

Ontologies

Keywords
   Biological processRhamnose metabolism
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processrhamnose catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

rhamnulokinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 489489Rhamnulokinase HAMAP MF_01535
PRO_0000297521

Regions

Region236 – 2383Substrate binding By similarity

Sites

Binding site141ATP By similarity
Binding site2591ATP By similarity
Binding site2961Substrate By similarity
Binding site3041ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0TAF9 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 02F0D88AC4AC8F7A

FASTA48954,115
        10         20         30         40         50         60 
MTFRNCVAVD LGASSGRVML ARYERECRSL TLREIHRFNN GLHSQNGYVT WNVDRLESAI 

        70         80         90        100        110        120 
RLGLNKVCEE GIRIDSIGID TWGVDFVLLD QQGQRVGLPV AYRDSRTNGL MAQAQQQLGK 

       130        140        150        160        170        180 
RDIYQRSGIQ FLPFNTIYQL RALTEQQPEL IPHIAHALLI PDYFSYRLTG KMNWEYTNAT 

       190        200        210        220        230        240 
TTQLVNINSD DWDESLLAWS GANKAWFGRP THPGNVIGHW ICPQGNEIPV VAVASHDTAS 

       250        260        270        280        290        300 
AVIASPLNGS RAAYLSSGTW SLMGFESQTP FTNDTALAAN ITNEGGAEGR YRVLKNIMGL 

       310        320        330        340        350        360 
WLLQRVLQER QINDLPALIA ATQALPACRF IINPNDDRFI NPDEMCSEIQ AACRETAQPI 

       370        380        390        400        410        420 
PESDAELARC IFDSLALLYA DVLHELAQLR GEDFSQLHIV GGGCQNALLN QLCADACGIR 

       430        440        450        460        470        480 
VIAGPVEAST LGNIGIQLMT LDELNNVDDF RQVVSTTANL TTFTPNPDSE IAHYVAQIHS 


TRQTKELCA

« Hide

References

[1]"Role of pathogenicity island-associated integrases in the genome plasticity of uropathogenic Escherichia coli strain 536."
Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U., Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J.
Mol. Microbiol. 61:584-595(2006) [PubMed: 16879640] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 536 / UPEC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000247 Genomic DNA. Translation: ABG72070.1.
RefSeqYP_671971.1. NC_008253.1.

3D structure databases

ProteinModelPortalQ0TAF9.
SMRQ0TAF9. Positions 2-480.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0TAF9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000045804; EBESCP00000043993; EBESCG00000044854.
GeneID4189734.
GenomeReviewsGene locus ECP_4114 in contig CP000247_GR.
KEGGecp:ECP_4114.
NMPDRfig|340197.3.peg.2774.
PATRIC18199133. VBIEscCol77757_4159.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1070.
GeneTreeEBGT00050000009230.
HOGENOMHBG313195.
OMAKENYTNE.
PhylomeDBQ0TAF9.
ProtClustDBPRK10640.

Enzyme and pathway databases

BioCycECOL362663:ECP_4114-MONOMER.

Family and domain databases

HAMAPMF_01535. Rhamnulokinase.
[Tree]
InterProIPR000577. Carb_kinase_FGGY.
IPR018485. Carb_kinase_FGGY_C.
IPR018484. Carb_kinase_FGGY_N.
IPR013449. Rhamnulokinase.
[Graphical view]
KOK00848.
PANTHERPTHR10196. FGGY_kin. 1 hit.
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR02627. Rhamnulo_kin. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRHAB_ECOL5
AccessionPrimary (citable) accession number: Q0TAF9
Entry history
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: September 5, 2006
Last modified: January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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