ID   UBIC_ECOL5              Reviewed;         165 AA.
AC   Q0TA23;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   16-JUN-2009, entry version 20.
DE   RecName: Full=Chorismate--pyruvate lyase;
DE            Short=CL;
DE            Short=CPL;
DE            EC=4.1.3.40;
GN   Name=ubiC; OrderedLocusNames=ECP_4256;
OS   Escherichia coli O6:K15:H31 (strain 536 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=362663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16879640; DOI=10.1111/j.1365-2958.2006.05255.x;
RA   Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U.,
RA   Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J.;
RT   "Role of pathogenicity island-associated integrases in the genome
RT   plasticity of uropathogenic Escherichia coli strain 536.";
RL   Mol. Microbiol. 61:584-595(2006).
CC   -!- FUNCTION: Removes the pyruvyl group from chorismate, with
CC       concomitant aromatization of the ring, to provide 4-
CC       hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity).
CC   -!- CATALYTIC ACTIVITY: Chorismate = 4-hydroxybenzoate + pyruvate.
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC   -!- SUBUNIT: Monomer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the ubiC family.
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DR   EMBL; CP000247; ABG72206.1; -; Genomic_DNA.
DR   RefSeq; YP_672107.1; -.
DR   SMR; Q0TA23; 2-165.
DR   GeneID; 4187957; -.
DR   GenomeReviews; CP000247_GR; ECP_4256.
DR   KEGG; ecp:ECP_4256; -.
DR   HOGENOM; Q0TA23; -.
DR   OMA; Q0TA23; WGRRSRF.
DR   BioCyc; ECOL362663:ECP_4256-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008813; F:chorismate lyase activity; IEA:HAMAP.
DR   GO; GO:0042866; P:pyruvate biosynthetic process; IEA:HAMAP.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_01632; -; 1.
DR   InterPro; IPR007440; Chorismate_lyase.
DR   Pfam; PF04345; Chor_lyase; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Lyase; Pyruvate;
KW   Ubiquinone biosynthesis.
FT   CHAIN         1    165       Chorismate--pyruvate lyase.
FT                                /FTId=PRO_0000255908.
FT   BINDING      35     35       Substrate; via amide nitrogen (By
FT                                similarity).
FT   BINDING      77     77       Substrate (By similarity).
FT   BINDING     115    115       Substrate; via amide nitrogen (By
FT                                similarity).
SQ   SEQUENCE   165 AA;  18808 MW;  7705434B48859FB6 CRC64;
     MSHPALTQLR ALRYFTEIPA LEPQLLDWLL LEDSMTKRFE QQGKTVSVTM IREGFVEQNE
     IPEELPLLPK ESRYWLREIL LCADGEPWLA GRTVVPVSTL SGPELALQKL GKTPLGRYLF
     TSSTLTRDFI EIGRDAGLWG RRSRLRLSGK PLLLTELFLP ASPLY
//