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Q0T8P1

- LFTR_SHIF8

UniProt

Q0T8P1 - LFTR_SHIF8

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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Shigella flexneri serotype 5b (strain 8401)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

  1. leucyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. protein catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

BioCyciSFLE373384:GHZM-875-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:SFV_0876
OrganismiShigella flexneri serotype 5b (strain 8401)
Taxonomic identifieri373384 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeShigella
ProteomesiUP000000659: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 234234Leucyl/phenylalanyl-tRNA--protein transferasePRO_0000304363Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi373384.SFV_0876.

Structurei

3D structure databases

ProteinModelPortaliQ0T8P1.
SMRiQ0T8P1. Positions 1-232.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2360.
HOGENOMiHOG000102325.
KOiK00684.
OMAiWSPDPRG.
OrthoDBiEOG6WX4R3.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0T8P1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRLVQLSRHS IAFPSPEGAL REPNGLLALG GDLSPARLLM AYQRGIFPWF
60 70 80 90 100
SPGDPILWWS PDPRAVLWPE SLHISRSMKR FHKRSPYRVT MNYAFGQVIE
110 120 130 140 150
GCASDREEGT WITRGVVEAY HRLHELGHAH SIEVWREDEL VAGMYGVAQG
160 170 180 190 200
TLFCGESMFS RMENASKTAL LVFCEEFIGH AGKLIDCQVL NDHTASLGAC
210 220 230
EIPRRDYLNY LNQMRLGRLP NNFWVPRCLF SPQE
Length:234
Mass (Da):26,647
Last modified:September 5, 2006 - v1
Checksum:i85D1A730D2482FD4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000266 Genomic DNA. Translation: ABF03101.1.
RefSeqiYP_688406.1. NC_008258.1.

Genome annotation databases

EnsemblBacteriaiABF03101; ABF03101; SFV_0876.
GeneIDi4208942.
KEGGisfv:SFV_0876.
PATRICi18724920. VBIShiFle33408_0988.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000266 Genomic DNA. Translation: ABF03101.1 .
RefSeqi YP_688406.1. NC_008258.1.

3D structure databases

ProteinModelPortali Q0T8P1.
SMRi Q0T8P1. Positions 1-232.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 373384.SFV_0876.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABF03101 ; ABF03101 ; SFV_0876 .
GeneIDi 4208942.
KEGGi sfv:SFV_0876.
PATRICi 18724920. VBIShiFle33408_0988.

Phylogenomic databases

eggNOGi COG2360.
HOGENOMi HOG000102325.
KOi K00684.
OMAi WSPDPRG.
OrthoDBi EOG6WX4R3.

Enzyme and pathway databases

BioCyci SFLE373384:GHZM-875-MONOMER.

Family and domain databases

HAMAPi MF_00688. Leu_Phe_trans.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view ]
Pfami PF03588. Leu_Phe_trans. 1 hit.
[Graphical view ]
SUPFAMi SSF55729. SSF55729. 1 hit.
TIGRFAMsi TIGR00667. aat. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Shigella flexneri 5b and comparison with Shigella flexneri 2a."
    Nie H., Yang F., Zhang X., Yang J., Chen L., Wang J., Xiong Z., Peng J., Sun L., Dong J., Xue Y., Xu X., Chen S., Yao Z., Shen Y., Jin Q.
    BMC Genomics 7:173-173(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 8401.

Entry informationi

Entry nameiLFTR_SHIF8
AccessioniPrimary (citable) accession number: Q0T8P1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 5, 2006
Last modified: October 29, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3