Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q0T6J2

- 6PGL_SHIF8

UniProt

Q0T6J2 - 6PGL_SHIF8

Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Shigella flexneri serotype 5b (strain 8401)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (05 Sep 2006)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.UniRule annotation

    Catalytic activityi

    6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. 6-phosphogluconolactonase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. pentose-phosphate shunt Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Glucose metabolism

    Enzyme and pathway databases

    BioCyciSFLE373384:GHZM-749-MONOMER.
    UniPathwayiUPA00115; UER00409.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    6-phosphogluconolactonaseUniRule annotation (EC:3.1.1.31UniRule annotation)
    Short name:
    6-P-gluconolactonaseUniRule annotation
    Gene namesi
    Name:pglUniRule annotation
    Ordered Locus Names:SFV_0750
    OrganismiShigella flexneri serotype 5b (strain 8401)
    Taxonomic identifieri373384 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeShigella
    ProteomesiUP000000659: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 3313316-phosphogluconolactonasePRO_0000291471Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei287 – 2871N6-acetyllysineUniRule annotation

    Keywords - PTMi

    Acetylation

    Interactioni

    Protein-protein interaction databases

    STRINGi373384.SFV_0750.

    Structurei

    3D structure databases

    ProteinModelPortaliQ0T6J2.
    SMRiQ0T6J2. Positions 1-331.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cycloisomerase 2 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2706.
    HOGENOMiHOG000257418.
    KOiK07404.
    OMAiDKRFLYV.
    OrthoDBiEOG615VK7.

    Family and domain databases

    Gene3Di2.130.10.10. 1 hit.
    HAMAPiMF_01605. 6P_gluconolactonase.
    InterProiIPR022528. 6-phosphogluconolactonase_YbhE.
    IPR019405. Lactonase_7-beta_prop.
    IPR011045. N2O_reductase_N.
    IPR015943. WD40/YVTN_repeat-like_dom.
    [Graphical view]
    PfamiPF10282. Lactonase. 1 hit.
    [Graphical view]
    SUPFAMiSSF50974. SSF50974. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q0T6J2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKQTVYIASP ESQQIHVWNL NHEGALTLTQ VVDVPGQVQP MVVSPDKRYL    50
    YVGVRPEFRV LAYRIAPDDG ALTFAAESVL PGSPTHISTD HQGQFVFVGS 100
    YNAGNVSVTR LEDGLPVGVV DVVEGLDGCH SANISPDNRT LWVPALKQDR 150
    ICLFTVSDDG HLVAQDPAEV TTVEGAGPRH MVFHPNEQYA YCVNELNSSV 200
    DVWELKDPHG NIECVQTLDM MPENFSDTRW AADIHITPDG RHLYACDRTA 250
    SLITVFSVSE DGSVLSKEGF QPTETQPRGF NVDYSGKYLI AAGQKSHHIS 300
    VYEIVGEQGL LHEKGRYAVG QGPMWVVVNA H 331
    Length:331
    Mass (Da):36,362
    Last modified:September 5, 2006 - v1
    Checksum:iB1C7AF3CF9781A9B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000266 Genomic DNA. Translation: ABF02984.1.
    RefSeqiYP_688289.1. NC_008258.1.

    Genome annotation databases

    EnsemblBacteriaiABF02984; ABF02984; SFV_0750.
    GeneIDi4207418.
    KEGGisfv:SFV_0750.
    PATRICi18724643. VBIShiFle33408_0851.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000266 Genomic DNA. Translation: ABF02984.1 .
    RefSeqi YP_688289.1. NC_008258.1.

    3D structure databases

    ProteinModelPortali Q0T6J2.
    SMRi Q0T6J2. Positions 1-331.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 373384.SFV_0750.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABF02984 ; ABF02984 ; SFV_0750 .
    GeneIDi 4207418.
    KEGGi sfv:SFV_0750.
    PATRICi 18724643. VBIShiFle33408_0851.

    Phylogenomic databases

    eggNOGi COG2706.
    HOGENOMi HOG000257418.
    KOi K07404.
    OMAi DKRFLYV.
    OrthoDBi EOG615VK7.

    Enzyme and pathway databases

    UniPathwayi UPA00115 ; UER00409 .
    BioCyci SFLE373384:GHZM-749-MONOMER.

    Family and domain databases

    Gene3Di 2.130.10.10. 1 hit.
    HAMAPi MF_01605. 6P_gluconolactonase.
    InterProi IPR022528. 6-phosphogluconolactonase_YbhE.
    IPR019405. Lactonase_7-beta_prop.
    IPR011045. N2O_reductase_N.
    IPR015943. WD40/YVTN_repeat-like_dom.
    [Graphical view ]
    Pfami PF10282. Lactonase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50974. SSF50974. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Shigella flexneri 5b and comparison with Shigella flexneri 2a."
      Nie H., Yang F., Zhang X., Yang J., Chen L., Wang J., Xiong Z., Peng J., Sun L., Dong J., Xue Y., Xu X., Chen S., Yao Z., Shen Y., Jin Q.
      BMC Genomics 7:173-173(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 8401.

    Entry informationi

    Entry namei6PGL_SHIF8
    AccessioniPrimary (citable) accession number: Q0T6J2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 12, 2007
    Last sequence update: September 5, 2006
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3