Reviewed, UniProtKB/Swiss-Prot Q0T2N9 (GLPB_SHIF8)

Names and origin

Protein names

Recommended name:
    Anaerobic glycerol-3-phosphate dehydrogenase subunit B
      Short name=Anaerobic G-3-P dehydrogenase subunit B
      Short name=Anaerobic G3Pdhase B
    EC=1.1.5.3

Gene names

Name:	glpB
Ordered Locus Names:	SFV_2314

Organism

Shigella flexneri serotype 5b (strain 8401) [Complete proteome] [HAMAP]

Taxonomic identifier

373384 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Shigella

Protein attributes

Sequence length	419 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor By similarity.
Catalytic activity	sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol. HAMAP MF_00753
Cofactor	FMN By similarity.
Pathway	Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1. HAMAP MF_00753
Subunit structure	Composed of a catalytic glpA/B dimer and of membrane bound glpC By similarity.
Sequence similarities	Belongs to the anaerobic G-3-P dehydrogenase subunit B family.

Ontologies

Keywords
Ligand	FMN Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro glycerol-3-phosphate dehydrogenase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 419	419	Anaerobic glycerol-3-phosphate dehydrogenase subunit B HAMAP MF_00753		PRO_1000046608

Sequences

	Sequence		Length	Mass (Da)
	Q0T2N9-1 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: A430A14D77D3207C	FASTA	419	45,301
	10 20 30 40 50 60 MRFDTVIMGG GLAGLLCGLQ LQKHGLRCAI VTRGQSALHF SSGSLDLLSH LPDGQPVADI 70 80 90 100 110 120 HSGLESLRQQ APAHPYSLLG PQRVLDLACQ AQALIAESGA QLQGSVELAH QRITPLGTLR 130 140 150 160 170 180 ATWLSSPEVP VWPLPAKKIC VVGISGLMDF QAHLAAASLR ELDLSVETAE IELPELDVLR 190 200 210 220 230 240 NNATEFRAVN IARFLDNEEN WPLLLDALIP VANTCEMILM PACFGLADDK LWRWLNEKLP 250 260 270 280 290 300 CSLMLLPTLA PSVLGIRLQN QLQRQFVRQG GVWMPGDEVK KVTCKNGVVN EIWTRNHADI 310 320 330 340 350 360 PLRPRFAVLA SGSFFSGGLV AERNGIREPI LGLDVLQTAT RGEWYKGDFF APQPWQQFGV 370 380 390 400 410 TTDETLRPSQ AGQTIENLFA IGSVLGGFDP IAQGCGGGVC AVSALHAAQQ IAQRAGGQQ

References

[1]

"Complete genome sequence of Shigella flexneri 5b and comparison with Shigella flexneri 2a." Nie H., Yang F., Zhang X., Yang J., Chen L., Wang J., Xiong Z., Peng J., Sun L., Dong J., Xue Y., Xu X., Chen S., Yao Z., Shen Y., Jin Q. BMC Genomics 7:173-173(2006) [PubMed: 16822325] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000266 Genomic DNA. Translation: ABF04426.1.
RefSeq	YP_689731.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4211115.
GenomeReviews	Gene locus SFV_2314 in contig CP000266_GR.
KEGG	sfv:SFV_2314.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q0T2N9.
OMA	Q0T2N9. TWLSQPF.
Enzyme and pathway databases
BioCyc	SFLE373384:SFV_2314-MON.
Family and domain databases
HAMAP	MF_00753. [Tree]
InterPro	IPR009158. Anaerobic_glycerol3P_DH_bsu. IPR003953. FAD_bind2_N. [Graphical view]
Pfam	PF00890. FAD_binding_2. 1 hit. [Graphical view]
PIRSF	PIRSF000141. Anaerobic_G3P_dh. 1 hit.
TIGRFAMs	TIGR03378. glycerol3P_GlpB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLPB_SHIF8

Accession

Primary (citable) accession number: Q0T2N9

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 5, 2006
Last modified:	June 16, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)