ID   NANE_SHIF8              Reviewed;         229 AA.
AC   Q0T067;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   16-JUN-2009, entry version 21.
DE   RecName: Full=Putative N-acetylmannosamine-6-phosphate 2-epimerase;
DE            EC=5.1.3.9;
DE   AltName: Full=ManNAc-6-P epimerase;
GN   Name=nanE; OrderedLocusNames=SFV_3248;
OS   Shigella flexneri serotype 5b (strain 8401).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=373384;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16822325; DOI=10.1186/1471-2164-7-173;
RA   Nie H., Yang F., Zhang X., Yang J., Chen L., Wang J., Xiong Z.,
RA   Peng J., Sun L., Dong J., Xue Y., Xu X., Chen S., Yao Z., Shen Y.,
RA   Jin Q.;
RT   "Complete genome sequence of Shigella flexneri 5b and comparison with
RT   Shigella flexneri 2a.";
RL   BMC Genomics 7:173-173(2006).
CC   -!- FUNCTION: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to
CC       N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential).
CC   -!- CATALYTIC ACTIVITY: N-acyl-D-glucosamine 6-phosphate = N-acyl-D-
CC       mannosamine 6-phosphate.
CC   -!- PATHWAY: Amino-sugar metabolism; N-acetylneuraminic acid
CC       degradation; D-fructose 6-phosphate from N-acetylneuraminic acid:
CC       step 3/5.
CC   -!- SIMILARITY: Belongs to the nanE family.
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DR   EMBL; CP000266; ABF05298.1; -; Genomic_DNA.
DR   RefSeq; YP_690603.1; -.
DR   GeneID; 4209286; -.
DR   GenomeReviews; CP000266_GR; SFV_3248.
DR   KEGG; sfv:SFV_3248; -.
DR   HOGENOM; Q0T067; -.
DR   OMA; Q0T067; YNTPELA.
DR   BioCyc; SFLE373384:SFV_3248-MON; -.
DR   GO; GO:0047465; F:N-acylglucosamine-6-phosphate 2-epimerase a...; IEA:EC.
DR   GO; GO:0006051; P:N-acetylmannosamine metabolic process; IEA:HAMAP.
DR   HAMAP; MF_01235; -; 1.
DR   InterPro; IPR007260; NanE.
DR   Pfam; PF04131; NanE; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Complete proteome; Isomerase.
FT   CHAIN         1    229       Putative N-acetylmannosamine-6-phosphate
FT                                2-epimerase.
FT                                /FTId=PRO_0000301482.
SQ   SEQUENCE   229 AA;  24088 MW;  FA6DB3F36FEDCEFE CRC64;
     MSLLAQLDQK IAANGGLIVS CQPVPDSPLD KPEIVAAMAL AAEQAGAVAI RIEGVANLQA
     TRAVVSVPII GIVKRDLEDS PVRITAYIED VDALAQAGAD IIAIDGTDRP RPVPVETLLA
     RIHHHGLLAM TDCSTPEDGL ACQKLGAEII GTTLSGYTTP ETPEEPDLAL VKTLSEAGCR
     VIAEGRYNTP AQAADAMRHG AWAVTVGSAI TRLEHICQWY NTAMKKAVL
//