Q0SZ94 (RHAB_SHIF8) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Rhamnulokinase
EC=2.7.1.5

Alternative name(s):
Rhamnulose kinase

Gene names

Name:	rhaB
Ordered Locus Names:	SFV_3591

Organism

Shigella flexneri serotype 5b (strain 8401) [Complete proteome] [HAMAP]

Taxonomic identifier

373384 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Shigella

Protein attributes

Sequence length	489 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate. HAMAP MF_01535
Pathway	Carbohydrate degradation; L-rhamnose degradation; glycerone phosphate from L-rhamnose: step 2/3. HAMAP MF_01535
Sequence similarities	Belongs to the rhamnulokinase family.

Ontologies

Keywords
Biological process	Rhamnose metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	rhamnose catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW rhamnulokinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 489	489	Rhamnulokinase HAMAP MF_01535		PRO_0000297523
Regions
	Region	236 – 238	3	Substrate binding By similarity
Sites
	Binding site	14	1	ATP By similarity
	Binding site	259	1	ATP By similarity
	Binding site	296	1	Substrate By similarity
	Binding site	304	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q0SZ94 [UniParc]. Last modified September 5, 2006. Version 1. Checksum: FB02AA6E932107C3	FASTA	489	54,050
	10 20 30 40 50 60 MTFRNCVAVD LGASSGRVML ARYERECRSL TLREIHRFNN GLHSQNGYVT WDVDSLESAI 70 80 90 100 110 120 RLGLNKVCEE GIRIDSIGID TWGVDFVLLD QQGQRVGLPV AYRDSRTNGL MPQAQQQLGK 130 140 150 160 170 180 RDIYQRSGIQ FLPFNTLYQL RALTEQQPEL IPHIAHALLM PDYFSYRLTG KMNWEYTNAT 190 200 210 220 230 240 TTQLVNINSD DWDESLLAWS GANKAWFGRP THPGNVIGHW ICPQGNEIPV VAVASHDTAS 250 260 270 280 290 300 AVIASPLNGS RAAYLSSGTW SLMGFESQTP FTNDTALAAN ITNEGGAEGR YRVLKNIMGL 310 320 330 340 350 360 WLLQRVLQER QINDLPALIA ATQALPACRF IINPNDDRFI NPDEMCSEIQ AACRETAQPI 370 380 390 400 410 420 PGSDAELARC IFDSLALLYA DVLHELAQLR GEDFSQLHIV GGGCQNTLLN QLCADACGIR 430 440 450 460 470 480 VIAGPVEAST LGNIGIELMT LDELNNVDDF RQVVSTTANL TTFTPNPDSE IAHYVAQIHS TRQTKELCA

References

[1]

"Complete genome sequence of Shigella flexneri 5b and comparison with Shigella flexneri 2a." Nie H., Yang F., Zhang X., Yang J., Chen L., Wang J., Xiong Z., Peng J., Sun L., Dong J., Xue Y., Xu X., Chen S., Yao Z., Shen Y., Jin Q. BMC Genomics 7:173-173(2006) [PubMed: 16822325] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 8401.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000266 Genomic DNA. Translation: ABF05621.1.
RefSeq	YP_690926.1. NC_008258.1.
3D structure databases
ProteinModelPortal	Q0SZ94.
SMR	Q0SZ94. Positions 2-480.
ModBase	Search...
Protein-protein interaction databases
STRING	Q0SZ94.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000097416; EBESCP00000093612; EBESCG00000096460.
GeneID	4207544.
GenomeReviews	Gene locus SFV_3591 in contig CP000266_GR.
KEGG	sfv:SFV_3591.
PATRIC	18731290. VBIShiFle33408_4100.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1070.
GeneTree	EBGT00050000009230.
HOGENOM	HBG313195.
OMA	KENYTNE.
ProtClustDB	PRK10640.
Enzyme and pathway databases
BioCyc	SFLE373384:SFV_3591-MONOMER.
Family and domain databases
HAMAP	MF_01535. Rhamnulokinase. [Tree]
InterPro	IPR000577. Carb_kinase_FGGY. IPR018485. Carb_kinase_FGGY_C. IPR018484. Carb_kinase_FGGY_N. IPR013449. Rhamnulokinase. [Graphical view]
KO	K00848.
PANTHER	PTHR10196. FGGY_kin. 1 hit.
Pfam	PF02782. FGGY_C. 1 hit. PF00370. FGGY_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR02627. Rhamnulo_kin. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RHAB_SHIF8

Accession

Primary (citable) accession number: Q0SZ94

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 21, 2007
Last sequence update:	September 5, 2006
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program