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Q0SZ93 (RHAA_SHIF8) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
L-rhamnose isomerase
EC=5.3.1.14
Gene names
Name:rhaA
Ordered Locus Names:SFV_3592
OrganismShigella flexneri serotype 5b (strain 8401) [Complete proteome] [HAMAP]
Taxonomic identifier373384 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Shigella

Protein attributes

Sequence length419 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-rhamnose = L-rhamnulose. HAMAP MF_00541

Cofactor

Binds 1 manganese ion per subunit By similarity. HAMAP MF_00541

Pathway

Carbohydrate degradation; L-rhamnose degradation; glycerone phosphate from L-rhamnose: step 1/3. HAMAP MF_00541

Subunit structure

Homotetramer By similarity. HAMAP MF_00541

Subcellular location

Cytoplasm By similarity HAMAP MF_00541.

Sequence similarities

Belongs to the rhamnose isomerase family.

Ontologies

Keywords
   Biological processRhamnose metabolism
   Cellular componentCytoplasm
   LigandManganese
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processrhamnose metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionL-rhamnose isomerase activity

Inferred from electronic annotation. Source: EC

manganese ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 419419L-rhamnose isomerase HAMAP MF_00541
PRO_1000017722

Sites

Metal binding2621Manganese By similarity
Metal binding2941Manganese By similarity
Metal binding2961Manganese By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0SZ93 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: D23B96FDD53CEB7B

FASTA41947,109
        10         20         30         40         50         60 
MTTQLEQAWE LAKQRFAAVG IDVEEALRQL DRLPVSMHCW QGDDVSGFEN PEGSLTGGIQ 

        70         80         90        100        110        120 
ATGNYPGKAR NASELRADLE QAMRLIPGPK RLNLHAIYLE SDTPVSRDQI KPEHFKNWVE 

       130        140        150        160        170        180 
WAKANQLGLD FNPSCFSHPL SADGFTLSHP DDSIRQFWID HCKASRRVSA YFGEQLGTPS 

       190        200        210        220        230        240 
VMNIWIPDGM KDITVDRLAP RQRLLAALDE VISEKLNPAH HIDAVESKLF GIGAESYTVG 

       250        260        270        280        290        300 
SNEFYMGYAT SRQTALCLDA GHFHPTEVIS DKISAAMLYV PQLLLHVSRP VRWDSDHVVL 

       310        320        330        340        350        360 
LDDETQAIAS EIVRHDLFDR VHIGLDFFDA SINRIAAWVI GTRNMKKALL RALLEPTAEL 

       370        380        390        400        410 
RKLEAAGDYT ARLALLEEQK SLPRQAVWEM YCQRHDTPAG SEWLESVRAY EKAILSQRG

« Hide

References

[1]"Complete genome sequence of Shigella flexneri 5b and comparison with Shigella flexneri 2a."
Nie H., Yang F., Zhang X., Yang J., Chen L., Wang J., Xiong Z., Peng J., Sun L., Dong J., Xue Y., Xu X., Chen S., Yao Z., Shen Y., Jin Q.
BMC Genomics 7:173-173(2006) [PubMed: 16822325] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 8401.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000266 Genomic DNA. Translation: ABF05622.1.
RefSeqYP_690927.1. NC_008258.1.

3D structure databases

ProteinModelPortalQ0SZ93.
SMRQ0SZ93. Positions 2-418.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0SZ93.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000094682; EBESCP00000090878; EBESCG00000093726.
GeneID4207545.
GenomeReviewsGene locus SFV_3592 in contig CP000266_GR.
KEGGsfv:SFV_3592.
PATRIC18731292. VBIShiFle33408_4101.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG4806.
GeneTreeEBGT00050000011577.
HOGENOMHBG313138.
OMAVNLHAIY.
ProtClustDBPRK01076.

Enzyme and pathway databases

BioCycSFLE373384:SFV_3592-MONOMER.

Family and domain databases

HAMAPMF_00541. RhaA.
[Tree]
InterProIPR009308. Rhamnose_isomerase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KOK01813.
PfamPF06134. RhaA. 1 hit.
[Graphical view]
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR01748. RhaA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRHAA_SHIF8
AccessionPrimary (citable) accession number: Q0SZ93
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 5, 2006
Last modified: January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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