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Reviewed, UniProtKB/Swiss-Prot Q0SYT2 (ASNA_SHIF8)

Last modified February 9, 2010. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Aspartate--ammonia ligase
    EC=6.3.1.1
Alternative name(s):
    Asparagine synthetase A
Gene names
Name: asnA
Ordered Locus Names: SFV_3770
OrganismShigella flexneri serotype 5b (strain 8401) [Complete proteome] [HAMAP]
Taxonomic identifier373384 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeShigella

Protein attributes

Sequence length330 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine. HAMAP MF_00555

Pathway

Amino-acid biosynthesis; L-asparagine biosynthesis; L-asparagine from L-aspartate (ammonia route): step 1/1. HAMAP MF_00555

Subcellular location

Cytoplasm By similarity HAMAP MF_00555.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 330330Aspartate--ammonia ligase HAMAP MF_00555
PRO_1000017961

Sequences

Sequence LengthMass (Da)Tools
Q0SYT2-1 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: B637F46E14170BB7

FASTA33036,643
        10         20         30         40         50         60 
MKTAYIAKQR QISFVKSHFS RQLEERLGLI EVQAPILSRV GDGTQDNLSG CEKAVQVKVK 

        70         80         90        100        110        120 
ALPDAQFEVV HSLAKWKRQT LGQHDFSAGE GLYTHMKALR PDEDRLSPLH SVYVDQWDWE 

       130        140        150        160        170        180 
RVMGDGERQL STLKSTVEAI WAGIKATEAA VNEEFGLAPF LPDQIHFVHS QELLSRYPDL 

       190        200        210        220        230        240 
DAKGRERAIA KDLGAVFLVG IGGKLSDGHR HDVRAPDYDD WSTPSELGHA GLNGDILVWN 

       250        260        270        280        290        300 
PVLEDAFELS SMGIRVDADT LKHQLALTGD EDRLQLEWHQ ALLRGEMPQT IGGGIGQSRL 

       310        320        330 
TMLLLQLPHI GQVQCGVWPA AVRESVPSLL 

« Hide

References

[1]"Complete genome sequence of Shigella flexneri 5b and comparison with Shigella flexneri 2a."
Nie H., Yang F., Zhang X., Yang J., Chen L., Wang J., Xiong Z., Peng J., Sun L., Dong J., Xue Y., Xu X., Chen S., Yao Z., Shen Y., Jin Q.
BMC Genomics 7:173-173(2006) [PubMed: 16822325] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000266 Genomic DNA. Translation: ABF05783.1.
RefSeqYP_691088.1.

3D structure databases

SMRQ0SYT2. Positions 4-330.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0SYT2.

Genome annotation databases

GeneID4207774.
GenomeReviewsGene locus SFV_3770 in contig CP000266_GR.
KEGGsfv:SFV_3770.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2502.
HOGENOMHBG288146.
OMALNDNLNG.

Enzyme and pathway databases

BioCycSFLE373384:SFV_3770-MONOMER.

Family and domain databases

HAMAPMF_00555. AsnA.
[Tree]
InterProIPR006195. aa-tRNA-synth_II_cons-dom.
IPR004618. AsnA.
[Graphical view]
PfamPF03590. AsnA. 1 hit.
[Graphical view]
PIRSFPIRSF001555. Asp_ammon_ligase. 1 hit.
TIGRFAMsTIGR00669. asnA. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameASNA_SHIF8
AccessionPrimary (citable) accession number: Q0SYT2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 5, 2006
Last modified: February 9, 2010
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents