ID   NUDC_SHIF8              Reviewed;         257 AA.
AC   Q0SY04;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   16-JUN-2009, entry version 21.
DE   RecName: Full=NADH pyrophosphatase;
DE            EC=3.6.1.22;
GN   Name=nudC; OrderedLocusNames=SFV_4068;
OS   Shigella flexneri serotype 5b (strain 8401).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=373384;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16822325; DOI=10.1186/1471-2164-7-173;
RA   Nie H., Yang F., Zhang X., Yang J., Chen L., Wang J., Xiong Z.,
RA   Peng J., Sun L., Dong J., Xue Y., Xu X., Chen S., Yao Z., Shen Y.,
RA   Jin Q.;
RT   "Complete genome sequence of Shigella flexneri 5b and comparison with
RT   Shigella flexneri 2a.";
RL   BMC Genomics 7:173-173(2006).
CC   -!- CATALYTIC ACTIVITY: NAD(+) + H(2)O = AMP + NMN.
CC   -!- COFACTOR: Divalent ions. Manganese or magnesium (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the Nudix hydrolase family. NudC subfamily.
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DR   EMBL; CP000266; ABF06061.1; -; Genomic_DNA.
DR   RefSeq; YP_691366.1; -.
DR   SMR; Q0SY04; 1-257.
DR   GeneID; 4209202; -.
DR   GenomeReviews; CP000266_GR; SFV_4068.
DR   KEGG; sfv:SFV_4068; -.
DR   HOGENOM; Q0SY04; -.
DR   OMA; Q0SY04; SPCIIVA.
DR   BioCyc; SFLE373384:SFV_4068-MON; -.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP.
DR   GO; GO:0030145; F:manganese ion binding; IEA:HAMAP.
DR   GO; GO:0000210; F:NAD+ diphosphatase activity; IEA:HAMAP.
DR   HAMAP; MF_00297; -; 1.
DR   InterPro; IPR015375; NADH_PPase-like_N.
DR   InterPro; IPR000086; NUDIX_hydrolase_core.
DR   InterPro; IPR015376; Znr_NADH_PPase.
DR   Gene3D; G3DSA:3.90.79.10; NUDIX_hydrolase; 1.
DR   Pfam; PF00293; NUDIX; 1.
DR   Pfam; PF09296; NUDIX-like; 1.
DR   Pfam; PF09297; zf-NADH-PPase; 1.
DR   PROSITE; PS00893; NUDIX; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase; Magnesium; Manganese; NAD.
FT   CHAIN         1    257       NADH pyrophosphatase.
FT                                /FTId=PRO_1000021915.
FT   MOTIF       159    180       Nudix box.
SQ   SEQUENCE   257 AA;  29703 MW;  D488D3DD32A83FAB CRC64;
     MDRIIEKLDH GWWVVSHEQK LWLPKGELPY GEAANFDLVG QRALQIGEWQ GEPVWLIQQQ
     RRHDMGSVRQ VIDLDVGLFQ LAGRGVQLAE FYRSHKYCGY CGHEMYPSKT EWAMLCSHCR
     ERYYPQIAPC IIVAIRRDDS ILLAQHTRHR NGVHTVLAGF VEVGETLEQA VAREVMEESG
     IKVKNLRYVT SQPWPFPQSL MTAFMAEYDS GDIVIDPKEL LEANWYRYDD LPLLPPPGTV
     ARRLIEDTVA MCRAEYE
//