Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

L-ribulose-5-phosphate 3-epimerase UlaE

Gene

ulaE

Organism
Shigella flexneri serotype 5b (strain 8401)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate. Is involved in the anaerobic L-ascorbate utilization.UniRule annotation

Catalytic activityi

L-ribulose 5-phosphate = L-xylulose 5-phosphate.UniRule annotation

Pathwayi: L-ascorbate degradation

This protein is involved in step 3 of the subpathway that synthesizes D-xylulose 5-phosphate from L-ascorbate.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. Probable L-ascorbate-6-phosphate lactonase UlaG (yjfR)
  2. 3-keto-L-gulonate-6-phosphate decarboxylase UlaD (ulaD)
  3. L-ribulose-5-phosphate 3-epimerase UlaE (ulaE)
  4. L-ribulose-5-phosphate 4-epimerase UlaF (ulaF)
This subpathway is part of the pathway L-ascorbate degradation, which is itself part of Cofactor degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-xylulose 5-phosphate from L-ascorbate, the pathway L-ascorbate degradation and in Cofactor degradation.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciSFLE373384:GHZM-4349-MONOMER.
UniPathwayiUPA00263; UER00379.

Names & Taxonomyi

Protein namesi
Recommended name:
L-ribulose-5-phosphate 3-epimerase UlaEUniRule annotation (EC:5.1.3.22UniRule annotation)
Alternative name(s):
L-ascorbate utilization protein EUniRule annotation
L-xylulose-5-phosphate 3-epimeraseUniRule annotation
Gene namesi
Name:ulaEUniRule annotation
Ordered Locus Names:SFV_4353
OrganismiShigella flexneri serotype 5b (strain 8401)
Taxonomic identifieri373384 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeShigella
Proteomesi
  • UP000000659 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 284284L-ribulose-5-phosphate 3-epimerase UlaEPRO_1000070635Add
BLAST

Expressioni

Inductioni

Induced by L-ascorbate. Repressed by UlaR.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ0SX88.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L-ribulose-5-phosphate 3-epimerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000126090.
KOiK03079.
OMAiQAGMGHI.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_01951. UlaE. 1 hit.
InterProiIPR004560. L-Ru-5P_3-Epase.
IPR023492. L-Ru-5P_3-Epase_Enterobacteria.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR00542. hxl6Piso_put. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0SX88-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSKQIPLGI YEKALPAGEC WLERLRLAKT LGFDFVEMSV DETNERLSRL
60 70 80 90 100
DWSRVQRLAL VNAIVETGVR VPSMCLSAHR RFPLVSEDDA VRAQGLEIMR
110 120 130 140 150
KAIQFAQDVG IRVIQLSGYD VYYQEANNET RRRFRDGLKE SVEMASRAQV
160 170 180 190 200
TLAMEIMDYP LMNSISKALG YAHYLNNPWF QLYPDIGNLS AWDNDVQMEL
210 220 230 240 250
QAGIGHIVAV HVKDTKPGVF KNVPFGEGVV DFERCFETLK QSGYCGPYLI
260 270 280
EMWSETAEDP AAEVVKACDW VKARMAKAGM VEAA
Length:284
Mass (Da):32,079
Last modified:September 5, 2006 - v1
Checksum:i4138EA24F37E0ACE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000266 Genomic DNA. Translation: ABF06327.1.
RefSeqiWP_000949548.1. NC_008258.1.

Genome annotation databases

EnsemblBacteriaiABF06327; ABF06327; SFV_4353.
KEGGisfv:SFV_4353.
PATRICi18733043. VBIShiFle33408_4940.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000266 Genomic DNA. Translation: ABF06327.1.
RefSeqiWP_000949548.1. NC_008258.1.

3D structure databases

ProteinModelPortaliQ0SX88.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABF06327; ABF06327; SFV_4353.
KEGGisfv:SFV_4353.
PATRICi18733043. VBIShiFle33408_4940.

Phylogenomic databases

HOGENOMiHOG000126090.
KOiK03079.
OMAiQAGMGHI.

Enzyme and pathway databases

UniPathwayiUPA00263; UER00379.
BioCyciSFLE373384:GHZM-4349-MONOMER.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_01951. UlaE. 1 hit.
InterProiIPR004560. L-Ru-5P_3-Epase.
IPR023492. L-Ru-5P_3-Epase_Enterobacteria.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR00542. hxl6Piso_put. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiULAE_SHIF8
AccessioniPrimary (citable) accession number: Q0SX88
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: September 5, 2006
Last modified: September 7, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.