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Q0SWZ1

- GLGB1_CLOPS

UniProt

Q0SWZ1 - GLGB1_CLOPS

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Protein

1,4-alpha-glucan branching enzyme GlgB 1

Gene
glgB1, CPR_0081
Organism
Clostridium perfringens (strain SM101 / Type A)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei336 – 3361Nucleophile By similarity
Active sitei389 – 3891Proton donor By similarity

GO - Molecular functioni

  1. 1,4-alpha-glucan branching enzyme activity Source: UniProtKB-HAMAP
  2. cation binding Source: InterPro
  3. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

BioCyciCPER289380:GI76-90-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgB 1 (EC:2.4.1.18)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase 1
Alpha-(1->4)-glucan branching enzyme 1
Glycogen branching enzyme 1
Short name:
BE 1
Gene namesi
Name:glgB1
Ordered Locus Names:CPR_0081
OrganismiClostridium perfringens (strain SM101 / Type A)
Taxonomic identifieri289380 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000001824: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 6746741,4-alpha-glucan branching enzyme GlgB 1UniRule annotationPRO_0000260646Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi289380.CPR_0081.

Structurei

3D structure databases

ProteinModelPortaliQ0SWZ1.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0296.
HOGENOMiHOG000283037.
KOiK00700.
OMAiECHQNNI.
OrthoDBiEOG6JX7GT.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPiMF_00685. GlgB.
InterProiIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 2 hits.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 1 hit.
TIGRFAMsiTIGR01515. branching_enzym. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0SWZ1-1 [UniParc]FASTAAdd to Basket

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MTLVEVKDDK LEIKPVRLRK EKYKAQLENK IFNEDELYLF HEGRNYNAYN    50
FMGAHFTSEN RKRGVRFTLW APRAKNIFLV GDFSNWETKE ENKLNRINET 100
GLWSIFIPRL KEGIKYKYYI EQEDGKAVLK ADPYGIYSEV RPNTASILCE 150
KTKIRWSDKK WLNKREATNY FESPINIYEL HLGSWKRKDE DEFLSYDELS 200
VVLPKYVKEM GYTHVEFMPL NEHPLDASWG YQVTGYYSVT SRYGDIKGLK 250
RLINALHKND IGVILDWVPG HFCKDEQGLY MFDGTPTYEY EEKWKADNKG 300
WGTFNFDLGK PEVKSFLISN AFYFINEFHI DGLRVDAVSN MLYLNYGRNH 350
GEWIPNIYGG NENLEAIQFI KELNEAIKTY SKGVITIAEE STSWPNVTND 400
TEYGGLGFDF KWNMGWMNDT LEYNELDPIY RKYHHNKLTF PMMYNHSEKF 450
ILPISHDEVV HGKKSLIDKM QGDYWNKFSN LRAYMAYMYG HPGKKLMFMG 500
CEFGQFIEWR EYEELEWKLI DKFDMHRKTH NFFKDLNNFY KNNSELWELD 550
YDGDGFQWID ADNNEQSIYI FIRKSKNIEK YKIFVCNFTP MVYYDFNIGV 600
PEKGVYREIF NTDKKEYGGS GQVIKGNLFS RKGWCHNQPY TLTIKVPPMA 650
VSVFERIIEE NKTEEKIVKE DKYI 674
Length:674
Mass (Da):80,125
Last modified:September 5, 2006 - v1
Checksum:iCE0F1D56FAD0CC1E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000312 Genomic DNA. Translation: ABG86142.1.
RefSeqiWP_011591248.1. NC_008262.1.
YP_697420.1. NC_008262.1.

Genome annotation databases

EnsemblBacteriaiABG86142; ABG86142; CPR_0081.
GeneIDi4204755.
KEGGicpr:CPR_0081.
PATRICi19488429. VBICloPer122123_0070.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000312 Genomic DNA. Translation: ABG86142.1 .
RefSeqi WP_011591248.1. NC_008262.1.
YP_697420.1. NC_008262.1.

3D structure databases

ProteinModelPortali Q0SWZ1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 289380.CPR_0081.

Protein family/group databases

CAZyi CBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABG86142 ; ABG86142 ; CPR_0081 .
GeneIDi 4204755.
KEGGi cpr:CPR_0081.
PATRICi 19488429. VBICloPer122123_0070.

Phylogenomic databases

eggNOGi COG0296.
HOGENOMi HOG000283037.
KOi K00700.
OMAi ECHQNNI.
OrthoDBi EOG6JX7GT.

Enzyme and pathway databases

UniPathwayi UPA00164 .
BioCyci CPER289380:GI76-90-MONOMER.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPi MF_00685. GlgB.
InterProi IPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view ]
PANTHERi PTHR10357. PTHR10357. 1 hit.
Pfami PF00128. Alpha-amylase. 2 hits.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view ]
PIRSFi PIRSF000463. GlgB. 1 hit.
SUPFAMi SSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 1 hit.
TIGRFAMsi TIGR01515. branching_enzym. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SM101 / Type A.

Entry informationi

Entry nameiGLGB1_CLOPS
AccessioniPrimary (citable) accession number: Q0SWZ1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: September 5, 2006
Last modified: September 3, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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