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Q0SVB1 (SYQ_CLOPS) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine--tRNA ligase

EC=6.1.1.18
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS
Gene names
Name:glnS
Ordered Locus Names:CPR_0612
OrganismClostridium perfringens (strain SM101 / Type A) [Complete proteome] [HAMAP]
Taxonomic identifier289380 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length552 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP-Rule MF_00126

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00126

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00126.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutaminyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

glutamyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glutamine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 552552Glutamine--tRNA ligase HAMAP-Rule MF_00126
PRO_1000095485

Regions

Motif33 – 4311"HIGH" region HAMAP-Rule MF_00126
Motif266 – 2705"KMSKS" region HAMAP-Rule MF_00126

Sites

Binding site2691ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q0SVB1 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 1F7F17EAE88ABF3B

FASTA55264,061
        10         20         30         40         50         60 
MSNAEHSSNF IRNIIIDDLD SKKHDTIITR FPPEPNGYLH IGHAKSIVLN FELGKEFNGR 

        70         80         90        100        110        120 
TNLRFDDTNP IKEDTEYVES IKEDVHWLGY NWSELHFASN YFDEMYKRAL LLIKKGKAYV 

       130        140        150        160        170        180 
CDLTPEEIKE YRGTLTEPGK ESPYRNRSVE ENLDLFERMR KGEFEDGSKV LRAKIDMSSP 

       190        200        210        220        230        240 
NINFRDPIIY RIAHASHHNT GDKWCIYPMY DFAHPLEDAI EGITHSICTL EFADHRPLYD 

       250        260        270        280        290        300 
WFVKECEMEN IPRQIEFARL NITNTVMSKR KLKQLVDEGI VDGWDDPRMP TVAGLRRRGY 

       310        320        330        340        350        360 
TPKSIRNFCK AIGVAKADST VDYQMLEHFI REDLQETAPR AMAVINPLKL VITNYPEGKS 

       370        380        390        400        410        420 
EILEIENNPK DESAGKRAVT FSREIYIERE DFMENPPKKY FRLFPGNEVR LKGAYFVKCN 

       430        440        450        460        470        480 
EVIKDENGEV TEIHCTYDPE TKSGTGFTGR KVKGTIHWVD ANNCIPAEFR LYEPLILDDC 

       490        500        510        520        530        540 
EENEGKHFLE QINPNSLTIC KGFIEPSAKD AKPQDKYQLF RHGYFNVDPN FTSDDNLVFN 

       550 
RIVSLKSSFK LK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000312 Genomic DNA. Translation: ABG87127.1.
RefSeqYP_697939.1. NC_008262.1.

3D structure databases

ProteinModelPortalQ0SVB1.
SMRQ0SVB1. Positions 8-548.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING289380.CPR_0612.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABG87127; ABG87127; CPR_0612.
GeneID4205007.
KEGGcpr:CPR_0612.
PATRIC19489519. VBICloPer122123_0591.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0008.
HOGENOMHOG000259232.
KOK01886.
OMAHAGDKWF.
OrthoDBEOG6DRPF7.

Enzyme and pathway databases

BioCycCPER289380:GI76-632-MONOMER.

Family and domain databases

Gene3D1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPMF_00126. Gln_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF50715. SSF50715. 1 hit.
TIGRFAMsTIGR00440. glnS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYQ_CLOPS
AccessionPrimary (citable) accession number: Q0SVB1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 5, 2006
Last modified: May 14, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries