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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Clostridium perfringens (strain SM101 / Type A)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei66L-glutamineUniRule annotation1
Binding sitei210L-glutamineUniRule annotation1
Binding sitei229ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi34 – 36ATPUniRule annotation3
Nucleotide bindingi40 – 46ATPUniRule annotation7
Nucleotide bindingi259 – 260ATPUniRule annotation2
Nucleotide bindingi267 – 269ATPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCPER289380:GI76-632-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:CPR_0612
OrganismiClostridium perfringens (strain SM101 / Type A)
Taxonomic identifieri289380 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000001824 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000954851 – 552Glutamine--tRNA ligaseAdd BLAST552

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ0SVB1.
SMRiQ0SVB1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi33 – 43"HIGH" regionUniRule annotationAdd BLAST11
Motifi266 – 270"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000259232.
KOiK01886.
OMAiVTHSICT.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 3 hits.
HAMAPiMF_00126. Gln_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
PfamiView protein in Pfam
PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0SVB1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNAEHSSNF IRNIIIDDLD SKKHDTIITR FPPEPNGYLH IGHAKSIVLN
60 70 80 90 100
FELGKEFNGR TNLRFDDTNP IKEDTEYVES IKEDVHWLGY NWSELHFASN
110 120 130 140 150
YFDEMYKRAL LLIKKGKAYV CDLTPEEIKE YRGTLTEPGK ESPYRNRSVE
160 170 180 190 200
ENLDLFERMR KGEFEDGSKV LRAKIDMSSP NINFRDPIIY RIAHASHHNT
210 220 230 240 250
GDKWCIYPMY DFAHPLEDAI EGITHSICTL EFADHRPLYD WFVKECEMEN
260 270 280 290 300
IPRQIEFARL NITNTVMSKR KLKQLVDEGI VDGWDDPRMP TVAGLRRRGY
310 320 330 340 350
TPKSIRNFCK AIGVAKADST VDYQMLEHFI REDLQETAPR AMAVINPLKL
360 370 380 390 400
VITNYPEGKS EILEIENNPK DESAGKRAVT FSREIYIERE DFMENPPKKY
410 420 430 440 450
FRLFPGNEVR LKGAYFVKCN EVIKDENGEV TEIHCTYDPE TKSGTGFTGR
460 470 480 490 500
KVKGTIHWVD ANNCIPAEFR LYEPLILDDC EENEGKHFLE QINPNSLTIC
510 520 530 540 550
KGFIEPSAKD AKPQDKYQLF RHGYFNVDPN FTSDDNLVFN RIVSLKSSFK

LK
Length:552
Mass (Da):64,061
Last modified:September 5, 2006 - v1
Checksum:i1F7F17EAE88ABF3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000312 Genomic DNA. Translation: ABG87127.1.

Genome annotation databases

EnsemblBacteriaiABG87127; ABG87127; CPR_0612.
KEGGicpr:CPR_0612.

Similar proteinsi

Entry informationi

Entry nameiSYQ_CLOPS
AccessioniPrimary (citable) accession number: Q0SVB1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 5, 2006
Last modified: August 30, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families