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Q0STS8 (CAPPA_CLOPS) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase
Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppcA
Ordered Locus Names:CPR_1157
OrganismClostridium perfringens (strain SM101 / Type A) [Complete proteome] [HAMAP]
Taxonomic identifier289380 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length537 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP MF_01904

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP MF_01904

Cofactor

Magnesium By similarity. HAMAP MF_01904

Subunit structure

Homotetramer By similarity. HAMAP MF_01904

Sequence similarities

Belongs to the PEPCase type 2 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-KW

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular functionphosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 537537Phosphoenolpyruvate carboxylase HAMAP MF_01904
PRO_0000309595

Sequences

Sequence LengthMass (Da)Tools
Q0STS8 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 852DD1D696D703F0

FASTA53760,512
        10         20         30         40         50         60 
MKIPCSMMTQ HPDNVETYIS IQQEPAEAIK GLTPQDKGGL GIEEVMIDFE GKLTPYHQTS 

        70         80         90        100        110        120 
QIALGLISNG IIPGKDVRVT PRIPNANKES VFRQLMSIMS IIETNVQSKE LTGTLAISEV 

       130        140        150        160        170        180 
VVPMIETGKE ISEFQDRVNS VVDMGNKNYK TKLDLNSVRI IPLVEDVPAL VNIDRILDEH 

       190        200        210        220        230        240 
YQIEKSKGHV LKDLRIMIAR SDTAMSYGLI SGVLSVLMAV DGAYKWGEKH GVTISPILGC 

       250        260        270        280        290        300 
GSLPFRGHFS EENIDEILAT YSGIKTFTFQ SALRYDHGEE ATKHTVNELK AKIEESKPRN 

       310        320        330        340        350        360 
FSEEDKDLMK EFIGICSKHY LQTFLKVIDT VSFVSDFIPK NRDRLTKAKT GLEYNREVAN 

       370        380        390        400        410        420 
LDNVADLVKD EVLKQEILSI DNSKEYAVPR AISFTGAMYT LGMPPELMGM GRALNEIKTK 

       430        440        450        460        470        480 
YGQEGIDKLL EIYPILRKDL AFAARFANGG VSKKIIDEEA RQEYKEDMKY VNEILNLGLD 

       490        500        510        520        530 
YDFLNENEFY HTLLKTTKPI IMHLMGLEEN VMRNSTEELK ILNEWIVRMG KVRGSIG

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000312 Genomic DNA. Translation: ABG87702.1.
RefSeqYP_698479.1. NC_008262.1.

3D structure databases

ProteinModelPortalQ0STS8.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ0STS8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4206081.
GenomeReviewsGene locus CPR_1157 in contig CP000312_GR.
KEGGcpr:CPR_1157.
PATRIC19490609. VBICloPer122123_1135.
TIGRCPR_1157.

Phylogenomic databases

eggNOGCOG1892.
HOGENOMHBG538207.
ProtClustDBPRK13655.

Enzyme and pathway databases

BioCycCPER289380:CPR_1157-MONOMER.

Family and domain databases

HAMAPMF_01904. PEPcase_type2.
[Tree]
InterProIPR021135. PEP_COase.
IPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase.
[Graphical view]
Gene3DG3DSA:3.20.20.60. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
KOK01595.
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PIRSFPIRSF006677. UCP006677. 1 hit.
SUPFAMSSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
TIGRFAMsTIGR02751. PEPCase_arch. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCAPPA_CLOPS
AccessionPrimary (citable) accession number: Q0STS8
Entry history
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: September 5, 2006
Last modified: January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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