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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Clostridium perfringens (strain SM101 / Type A)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
Biological processCarbon dioxide fixation
LigandMagnesium

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:CPR_1157
OrganismiClostridium perfringens (strain SM101 / Type A)
Taxonomic identifieri289380 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000001824 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003095951 – 537Phosphoenolpyruvate carboxylaseAdd BLAST537

Proteomic databases

PRIDEiQ0STS8

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ0STS8
SMRiQ0STS8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000009826
KOiK01595
OMAiPAMNYGL

Family and domain databases

HAMAPiMF_01904 PEPcase_type2, 1 hit
InterProiView protein in InterPro
IPR007566 PEP_COase_arc-type
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PfamiView protein in Pfam
PF14010 PEPcase_2, 1 hit
PIRSFiPIRSF006677 UCP006677, 1 hit
SUPFAMiSSF51621 SSF51621, 1 hit
TIGRFAMsiTIGR02751 PEPCase_arch, 1 hit

Sequencei

Sequence statusi: Complete.

Q0STS8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIPCSMMTQ HPDNVETYIS IQQEPAEAIK GLTPQDKGGL GIEEVMIDFE
60 70 80 90 100
GKLTPYHQTS QIALGLISNG IIPGKDVRVT PRIPNANKES VFRQLMSIMS
110 120 130 140 150
IIETNVQSKE LTGTLAISEV VVPMIETGKE ISEFQDRVNS VVDMGNKNYK
160 170 180 190 200
TKLDLNSVRI IPLVEDVPAL VNIDRILDEH YQIEKSKGHV LKDLRIMIAR
210 220 230 240 250
SDTAMSYGLI SGVLSVLMAV DGAYKWGEKH GVTISPILGC GSLPFRGHFS
260 270 280 290 300
EENIDEILAT YSGIKTFTFQ SALRYDHGEE ATKHTVNELK AKIEESKPRN
310 320 330 340 350
FSEEDKDLMK EFIGICSKHY LQTFLKVIDT VSFVSDFIPK NRDRLTKAKT
360 370 380 390 400
GLEYNREVAN LDNVADLVKD EVLKQEILSI DNSKEYAVPR AISFTGAMYT
410 420 430 440 450
LGMPPELMGM GRALNEIKTK YGQEGIDKLL EIYPILRKDL AFAARFANGG
460 470 480 490 500
VSKKIIDEEA RQEYKEDMKY VNEILNLGLD YDFLNENEFY HTLLKTTKPI
510 520 530
IMHLMGLEEN VMRNSTEELK ILNEWIVRMG KVRGSIG
Length:537
Mass (Da):60,512
Last modified:September 5, 2006 - v1
Checksum:i852DD1D696D703F0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000312 Genomic DNA Translation: ABG87702.1

Genome annotation databases

EnsemblBacteriaiABG87702; ABG87702; CPR_1157
KEGGicpr:CPR_1157

Similar proteinsi

Entry informationi

Entry nameiCAPPA_CLOPS
AccessioniPrimary (citable) accession number: Q0STS8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: September 5, 2006
Last modified: May 23, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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