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Q0STN6

- PYRF_CLOPS

UniProt

Q0STN6 - PYRF_CLOPS

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Protein
Orotidine 5'-phosphate decarboxylase
Gene
pyrF, CPR_1199
Organism
Clostridium perfringens (strain SM101 / Type A)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Orotidine 5'-phosphate = UMP + CO2.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei97 – 971Proton donor By similarity

GO - Molecular functioni

  1. orotidine-5'-phosphate decarboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway
  2. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Biological processi

Pyrimidine biosynthesis

Enzyme and pathway databases

BioCyciCPER289380:GI76-1215-MONOMER.
UniPathwayiUPA00070; UER00120.

Names & Taxonomyi

Protein namesi
Recommended name:
Orotidine 5'-phosphate decarboxylase (EC:4.1.1.23)
Alternative name(s):
OMP decarboxylase
Short name:
OMPDCase
Short name:
OMPdecase
Gene namesi
Name:pyrF
Ordered Locus Names:CPR_1199
OrganismiClostridium perfringens (strain SM101 / Type A)
Taxonomic identifieri289380 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000001824: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 287287Orotidine 5'-phosphate decarboxylaseUniRule annotation
PRO_1000066466Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi289380.CPR_1199.

Structurei

3D structure databases

ProteinModelPortaliQ0STN6.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0284.
HOGENOMiHOG000245747.
KOiK01591.
OMAiCRTSNAG.
OrthoDBiEOG6DZF33.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_01215. OMPdecase_type2.
InterProiIPR013785. Aldolase_TIM.
IPR018089. OMPdecase_AS.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTiSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
TIGRFAMsiTIGR02127. pyrF_sub2. 1 hit.
PROSITEiPS00156. OMPDECASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0STN6-1 [UniParc]FASTAAdd to Basket

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MIADKLFEKV EKNGVVCVGL DTSLDYIPEE FKSKFSNESD MLFAFNKEII    50
DATLDVSACF KVQIAYYEAL GLKGLEAYKN TLSYLREKNA LIIADIKRGD 100
IAATAKMYAK AHFEGDFESD FITLNPYMGM DSIDPYLPYI EKNEKGVFVL 150
VRTSNKGAQD IEYLEAGDGK KVYDVVGEKL NTLGKNYLGK HGYSSIGGVV 200
GCTHQEEAKE MRDKLDTMPF LIPGYGAQGG TAKDVASYLK NGNGGIVNSS 250
RKILLAYKAM EDNKNFAECA RKEAISMRDS IREAILK 287
Length:287
Mass (Da):31,816
Last modified:September 5, 2006 - v1
Checksum:i8E9264A216A395C6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000312 Genomic DNA. Translation: ABG86353.1.
RefSeqiWP_011592196.1. NC_008262.1.
YP_698521.1. NC_008262.1.

Genome annotation databases

EnsemblBacteriaiABG86353; ABG86353; CPR_1199.
GeneIDi4204771.
KEGGicpr:CPR_1199.
PATRICi19490691. VBICloPer122123_1176.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000312 Genomic DNA. Translation: ABG86353.1 .
RefSeqi WP_011592196.1. NC_008262.1.
YP_698521.1. NC_008262.1.

3D structure databases

ProteinModelPortali Q0STN6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 289380.CPR_1199.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABG86353 ; ABG86353 ; CPR_1199 .
GeneIDi 4204771.
KEGGi cpr:CPR_1199.
PATRICi 19490691. VBICloPer122123_1176.

Phylogenomic databases

eggNOGi COG0284.
HOGENOMi HOG000245747.
KOi K01591.
OMAi CRTSNAG.
OrthoDBi EOG6DZF33.

Enzyme and pathway databases

UniPathwayi UPA00070 ; UER00120 .
BioCyci CPER289380:GI76-1215-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_01215. OMPdecase_type2.
InterProi IPR013785. Aldolase_TIM.
IPR018089. OMPdecase_AS.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00215. OMPdecase. 1 hit.
[Graphical view ]
SMARTi SM00934. OMPdecase. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
TIGRFAMsi TIGR02127. pyrF_sub2. 1 hit.
PROSITEi PS00156. OMPDECASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SM101 / Type A.

Entry informationi

Entry nameiPYRF_CLOPS
AccessioniPrimary (citable) accession number: Q0STN6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: September 5, 2006
Last modified: September 3, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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