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Q0STN1 (UPPP_CLOPS) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Ordered Locus Names:CPR_1204
OrganismClostridium perfringens (strain SM101 / Type A) [Complete proteome] [HAMAP]
Taxonomic identifier289380 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium

Protein attributes

Sequence length304 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 304304Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000290702

Regions

Transmembrane5 – 2521Helical; Potential
Transmembrane47 – 6721Helical; Potential
Transmembrane72 – 9221Helical; Potential
Transmembrane111 – 13121Helical; Potential
Transmembrane137 – 15721Helical; Potential
Transmembrane209 – 23123Helical; Potential
Transmembrane248 – 26821Helical; Potential
Transmembrane282 – 30221Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q0STN1 [UniParc].

Last modified September 5, 2006. Version 1.
Checksum: 6E800314D2552F72

FASTA30433,623
        10         20         30         40         50         60 
MGIDFLFILK ALIIAIVEGL TEFVPVSSTG HMILVGDLIH FNTQSGGFPE MYEVVIQLGA 

        70         80         90        100        110        120 
ILAVVVLYWR KISSSVVEFL SYIFSFIGLK ASGDKRKYEK RLAESKTGFR FGINVIIGTI 

       130        140        150        160        170        180 
PAAILGLLFH DEIKEYLFST KTVAIGFIVG GILLIVIENN FRKRAKRSKI VKDIDKMTYG 

       190        200        210        220        230        240 
QSLLVGCFQC LSLWPGMSRS ASTIMGGWIS GLSTTVATEF TFFLAIPAMV GASGLDLFKF 

       250        260        270        280        290        300 
DYSQMNATNL ISLILGFIVA FIVSLVVIDK FINYLKKKPM RIFAIYRVFA GIVLAILIFT 


KVIS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000312 Genomic DNA. Translation: ABG85316.1.
RefSeqYP_698526.1. NC_008262.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING289380.CPR_1204.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABG85316; ABG85316; CPR_1204.
GeneID4204038.
KEGGcpr:CPR_1204.
PATRIC19490701. VBICloPer122123_1181.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAWRKISSS.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycCPER289380:GI76-1220-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP_CLOPS
AccessionPrimary (citable) accession number: Q0STN1
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: September 5, 2006
Last modified: May 14, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families