Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q0ST19

- GSA_CLOPS

UniProt

Q0ST19 - GSA_CLOPS

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutamate-1-semialdehyde 2,1-aminomutase

Gene

hemL

Organism
Clostridium perfringens (strain SM101 / Type A)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-4-amino-5-oxopentanoate = 5-aminolevulinate.UniRule annotation

Cofactori

Pyridoxal phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. glutamate-1-semialdehyde 2,1-aminomutase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: InterPro
  3. transaminase activity Source: InterPro

GO - Biological processi

  1. protoporphyrinogen IX biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Porphyrin biosynthesis

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

BioCyciCPER289380:GI76-1432-MONOMER.
UniPathwayiUPA00251; UER00317.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate-1-semialdehyde 2,1-aminomutaseUniRule annotation (EC:5.4.3.8UniRule annotation)
Short name:
GSAUniRule annotation
Alternative name(s):
Glutamate-1-semialdehyde aminotransferaseUniRule annotation
Short name:
GSA-ATUniRule annotation
Gene namesi
Name:hemLUniRule annotation
Ordered Locus Names:CPR_1419
OrganismiClostridium perfringens (strain SM101 / Type A)
Taxonomic identifieri289380 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000001824: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 425425Glutamate-1-semialdehyde 2,1-aminomutasePRO_0000300903Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei265 – 2651N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi289380.CPR_1419.

Structurei

3D structure databases

ProteinModelPortaliQ0ST19.
SMRiQ0ST19. Positions 3-422.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0001.
HOGENOMiHOG000020210.
KOiK01845.
OMAiHGHANAF.
OrthoDBiEOG6QVRHN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPiMF_00375. HemL_aminotrans_3.
InterProiIPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00713. hemL. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0ST19-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDRNKEIFEE SKKYMPGGVN SPVRSFGSVG INPPVIKSGK GAMIKDENGN
60 70 80 90 100
EYIDFVLAWG PMILGHCDED VVEAIKKTSE ESIAFGASTK LELDLAKILC
110 120 130 140 150
ETLDNVDMIR MVNSGTEATM SAVKLARGYT KKDKIIKFAG CYHGHFDGFL
160 170 180 190 200
IEAGSGVLTE GIPGCLGVPE ESIKNTLIGI YNDEKQVEEL FEKYGNDIAG
210 220 230 240 250
IIIEPVAGNM GVVKCDPKFM RKLRELCDKY EALLIFDEVM CGFRVAYKGA
260 270 280 290 300
QTLFDVKPDL VTYAKIMGGG LPCGAYGGRR EIMENLSPLG GVYQAGTMSG
310 320 330 340 350
NPIVMSAGLA TVKKLYENPS YYDHIEKIGS KLEKGIIEIA KKKGLGLVVN
360 370 380 390 400
RQGGMMTLFF TDLKEVKCYD DVKTCDGERF KRYFLHMLNK GFNIPPSQFE
410 420
AMFLSVKHTE EHIDKFLEAF ESFEG
Length:425
Mass (Da):46,972
Last modified:September 19, 2006 - v1
Checksum:iA1FC7E498ABD03C0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000312 Genomic DNA. Translation: ABG87795.1.
RefSeqiWP_011592383.1. NC_008262.1.
YP_698738.1. NC_008262.1.

Genome annotation databases

EnsemblBacteriaiABG87795; ABG87795; CPR_1419.
GeneIDi4205980.
KEGGicpr:CPR_1419.
PATRICi19491129. VBICloPer122123_1394.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000312 Genomic DNA. Translation: ABG87795.1 .
RefSeqi WP_011592383.1. NC_008262.1.
YP_698738.1. NC_008262.1.

3D structure databases

ProteinModelPortali Q0ST19.
SMRi Q0ST19. Positions 3-422.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 289380.CPR_1419.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABG87795 ; ABG87795 ; CPR_1419 .
GeneIDi 4205980.
KEGGi cpr:CPR_1419.
PATRICi 19491129. VBICloPer122123_1394.

Phylogenomic databases

eggNOGi COG0001.
HOGENOMi HOG000020210.
KOi K01845.
OMAi HGHANAF.
OrthoDBi EOG6QVRHN.

Enzyme and pathway databases

UniPathwayi UPA00251 ; UER00317 .
BioCyci CPER289380:GI76-1432-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPi MF_00375. HemL_aminotrans_3.
InterProi IPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view ]
PANTHERi PTHR11986. PTHR11986. 1 hit.
Pfami PF00202. Aminotran_3. 1 hit.
[Graphical view ]
PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR00713. hemL. 1 hit.
PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SM101 / Type A.

Entry informationi

Entry nameiGSA_CLOPS
AccessioniPrimary (citable) accession number: Q0ST19
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 19, 2006
Last modified: October 29, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3