ID   MSRB_CLOPS              Reviewed;         147 AA.
AC   Q0SSL4;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   16-JUN-2009, entry version 22.
DE   RecName: Full=Peptide methionine sulfoxide reductase msrB;
DE            EC=1.8.4.12;
DE   AltName: Full=Peptide-methionine (R)-S-oxide reductase;
GN   Name=msrB; OrderedLocusNames=CPR_1577;
OS   Clostridium perfringens (strain SM101 / Type A).
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=289380;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16825665; DOI=10.1101/gr.5238106;
RA   Myers G.S.A., Rasko D.A., Cheung J.K., Ravel J., Seshadri R.,
RA   DeBoy R.T., Ren Q., Varga J., Awad M.M., Brinkac L.M., Daugherty S.C.,
RA   Haft D.H., Dodson R.J., Madupu R., Nelson W.C., Rosovitz M.J.,
RA   Sullivan S.A., Khouri H., Dimitrov G.I., Watkins K.L., Mulligan S.,
RA   Benton J., Radune D., Fisher D.J., Atkins H.S., Hiscox T., Jost B.H.,
RA   Billington S.J., Songer J.G., McClane B.A., Titball R.W., Rood J.I.,
RA   Melville S.B., Paulsen I.T.;
RT   "Skewed genomic variability in strains of the toxigenic bacterial
RT   pathogen, Clostridium perfringens.";
RL   Genome Res. 16:1031-1040(2006).
CC   -!- CATALYTIC ACTIVITY: Peptide-L-methionine + thioredoxin disulfide +
CC       H(2)O = peptide-L-methionine (R)-S-oxide + thioredoxin.
CC   -!- SIMILARITY: Belongs to the msrB Met sulfoxide reductase family.
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DR   EMBL; CP000312; ABG86968.1; -; Genomic_DNA.
DR   RefSeq; YP_698893.1; -.
DR   GeneID; 4205120; -.
DR   GenomeReviews; CP000312_GR; CPR_1577.
DR   KEGG; cpr:CPR_1577; -.
DR   TIGR; CPR_1577; -.
DR   HOGENOM; Q0SSL4; -.
DR   OMA; Q0SSL4; KYESGCG.
DR   GO; GO:0033743; F:peptide-methionine (R)-S-oxide reductase ac...; IEA:EC.
DR   GO; GO:0008113; F:peptide-methionine-(S)-S-oxide reductase ac...; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_01400; -; 1.
DR   InterPro; IPR002579; Methionine_sulphoxide_MsrB.
DR   Gene3D; G3DSA:2.170.150.20; MsrB; 1.
DR   Pfam; PF01641; SelR; 1.
DR   ProDom; PD004057; DUF25; 1.
DR   TIGRFAMs; TIGR00357; MsrB; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Oxidoreductase.
FT   CHAIN         1    147       Peptide methionine sulfoxide reductase
FT                                msrB.
FT                                /FTId=PRO_1000068267.
FT   ACT_SITE    120    120       Nucleophile (By similarity).
SQ   SEQUENCE   147 AA;  17145 MW;  CC1F7FE270D73A87 CRC64;
     MKYKKKEKEE LKKILTEEEY YVTQENGTER PFTNEYWDFN GEGIYVDITT GEPLFTSKDK
     FHSSCGWPAF SKPIDRSIIK EKVDKSHGMV RTEVRSKLGD SHLGHVFCDG PEELGGLRYC
     INSASLKFIP KEELKEKGYE EYLELFK
//