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Protein

16S rRNA (cytosine(967)-C(5))-methyltransferase

Gene

sun

Organism
Clostridium perfringens (strain SM101 / Type A)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei280S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei307S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei325S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei378NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotationImported, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciCPER289380:GI76-1723-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
16S rRNA (cytosine(967)-C(5))-methyltransferaseSAAS annotation (EC:2.1.1.176SAAS annotation)
Gene namesi
Name:sunImported
Ordered Locus Names:CPR_1712Imported
OrganismiClostridium perfringens (strain SM101 / Type A)Imported
Taxonomic identifieri289380 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000001824 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ0SS80.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini166 – 439SAM_MT_RSMB_NOPInterPro annotationAdd BLAST274

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000037300.
KOiK03500.
OMAiLRVNRQH.

Family and domain databases

Gene3Di1.10.940.10. 1 hit.
InterProiView protein in InterPro
IPR001678. MeTrfase_RsmB/NOP2.
IPR011023. Nop2p.
IPR006027. NusB_RsmB_TIM44.
IPR023267. RCMT.
IPR004573. rRNA_ssu_MeTfrase_B.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF01029. NusB. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
SUPFAMiSSF48013. SSF48013. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00446. nop2p. 1 hit.
TIGR00563. rsmB. 1 hit.
PROSITEiView protein in PROSITE
PS51686. SAM_MT_RSMB_NOP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0SS80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNARKIIVEI LDNVLLNGAY SNIEINKQFA SNDIDPKDKG LITEVVYGTI
60 70 80 90 100
KYKKMIDIIL SNFVADIGKI DESVVNILRS AIYQMKFLDR VPPYAIVNEA
110 120 130 140 150
VNLTKETEPN LAKFVNGVLR NYLRNENKNF KVGLRNNEAL CYDFSFDRWM
160 170 180 190 200
IEMFIKQYGK DDALRILRGL NTIPYVTVRV NTCKADYDEV YERLEEEGYD
210 220 230 240 250
IEEGAFSPEA IIIKKGSAIE KNKLYQEGLI TVQDESAMLV APLFDLKDDE
260 270 280 290 300
QVMDLCSAPG TKATHIGELM MNKGKVVAFD IHDHKLTLIK ENIDRLGLTN
310 320 330 340 350
VEVELGDATK INSKYINWAD RVLLDVPCSG LGIIRKKPEI KWNKKNNDLT
360 370 380 390 400
EVVKVQKEIL KNAWNYLREG GELVYSTCTL NKKENEEVID WFVEKNSDCE
410 420 430 440
VEKVFLGKAD NVVYNDNGSV TILPNKYMDG FFIAKLKKKE SK
Length:442
Mass (Da):50,488
Last modified:September 5, 2006 - v1
Checksum:i7FF30BA21F334F08
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000312 Genomic DNA. Translation: ABG87308.1.

Genome annotation databases

EnsemblBacteriaiABG87308; ABG87308; CPR_1712.
KEGGicpr:CPR_1712.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ0SS80_CLOPS
AccessioniPrimary (citable) accession number: Q0SS80
Entry historyiIntegrated into UniProtKB/TrEMBL: September 5, 2006
Last sequence update: September 5, 2006
Last modified: June 7, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported