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Protein

Glutamate decarboxylase

Gene

CPR_2029

Organism
Clostridium perfringens (strain SM101 / Type A)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciCPER289380:GI76-2040-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:CPR_2029Imported
OrganismiClostridium perfringens (strain SM101 / Type A)Imported
Taxonomic identifieri289380 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
ProteomesiUP000001824 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi289380.CPR_2029.

Structurei

3D structure databases

ProteinModelPortaliQ0SRB9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiDPDLVWD.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q0SRB9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLFGKNELGS QFETPIFGTV ESNEPIPKYK LAKKSIAPQV AYRLIKDDLL
60 70 80 90 100
DEGNARQNLA TFCQTYMDDE AVKLMSETLE KNAIDKSEYP QTTDMENRCV
110 120 130 140 150
NILADLWHAP KELNYMGTST VGSSEACMLG GMAMKFRWRN RAKALGMDVT
160 170 180 190 200
SKKPNLVISS GYQVCWEKFC VYWDIEMRLV PMDEQHMSIN VDKVLDYVDD
210 220 230 240 250
YTIGVVGILG ITYTGKYDDI KALDKKLEEY NKTAKITVPI HVDGASGAMF
260 270 280 290 300
APFIEPDLKW DFQLKNVVSI STSGHKYGLV YPGIGWVLWK DKEYLPQELV
310 320 330 340 350
FEVSYLGGKM PTMAINFSRS ASQILGQYYN FLRYGFEGYR QIHQRTKDVA
360 370 380 390 400
MYLSSELEKT GLFEIYNNGE NLPIVCYKLK DDVKVNWTLY DLADRLLMKG
410 420 430 440 450
WQVPAYPLPE DLQNVIIQRF VCRADLSRNL ADLLMRDLKA AIEDLNNARI
460
LSKTQVDNKG VQGFTH
Length:466
Mass (Da):53,200
Last modified:September 4, 2006 - v1
Checksum:i141317A798F66613
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000312 Genomic DNA. Translation: ABG85385.1.
RefSeqiYP_699338.1. NC_008262.1.

Genome annotation databases

EnsemblBacteriaiABG85385; ABG85385; CPR_2029.
GeneIDi4204019.
KEGGicpr:CPR_2029.
PATRICi19492363. VBICloPer122123_2004.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000312 Genomic DNA. Translation: ABG85385.1.
RefSeqiYP_699338.1. NC_008262.1.

3D structure databases

ProteinModelPortaliQ0SRB9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi289380.CPR_2029.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABG85385; ABG85385; CPR_2029.
GeneIDi4204019.
KEGGicpr:CPR_2029.
PATRICi19492363. VBICloPer122123_2004.

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiDPDLVWD.
OrthoDBiEOG6TFCPW.

Enzyme and pathway databases

BioCyciCPER289380:GI76-2040-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SM101 / Type AImported.

Entry informationi

Entry nameiQ0SRB9_CLOPS
AccessioniPrimary (citable) accession number: Q0SRB9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 4, 2006
Last sequence update: September 4, 2006
Last modified: March 3, 2015
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.