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Protein

Elongation factor Tu

Gene

tuf1

more
Organism
Clostridium perfringens (strain SM101 / Type A)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi81 – 85GTPUniRule annotation5
Nucleotide bindingi136 – 139GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis
LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tuf1UniRule annotation
Ordered Locus Names:CPR_2402
AND
Name:tuf2UniRule annotation
Ordered Locus Names:CPR_2416
OrganismiClostridium perfringens (strain SM101 / Type A)
Taxonomic identifieri289380 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000001824 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003373651 – 397Elongation factor TuAdd BLAST397

Proteomic databases

PRIDEiQ0SQC8

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ0SQC8
SMRiQ0SQC8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 206tr-type GAdd BLAST197

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni19 – 26G1By similarity8
Regioni60 – 64G2By similarity5
Regioni81 – 84G3By similarity4
Regioni136 – 139G4By similarity4
Regioni174 – 176G5By similarity3

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000229290
KOiK02358
OMAiYGHIDCP

Family and domain databases

CDDicd03697 EFTU_II, 1 hit
HAMAPiMF_00118_B EF_Tu_B, 1 hit
InterProiView protein in InterPro
IPR004161 EFTu-like_2
IPR033720 EFTU_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR009001 Transl_elong_EF1A/Init_IF2_C
IPR004541 Transl_elong_EFTu/EF1A_bac/org
IPR004160 Transl_elong_EFTu/EF1A_C
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PF03143 GTP_EFTU_D3, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF50465 SSF50465, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00485 EF-Tu, 1 hit
TIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q0SQC8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKAKFERSK PHVNIGTIGH VDHGKTTLTA AITTVLAQAG GAEAFKYDEI
60 70 80 90 100
DKAPEEKERG ITINTAHVEY ETANRHYAHV DCPGHADYVK NMITGAAQMD
110 120 130 140 150
GAILVCSAAD GPMPQTREHI LLSSRVGVDH IVVFLNKADM VDDEELLELV
160 170 180 190 200
EMEVRELLSE YNFPGDDIPV IKGSALVALE NPTDEAATAC IRELMDAVDS
210 220 230 240 250
YIPTPERATD KPFLMPVEDV FTITGRGTVA TGRVERGVLH VGDEVEVIGL
260 270 280 290 300
TEERRKTVVT GIEMFRKLLD EAQAGDNIGA LLRGIQRTDI ERGQVLAQVG
310 320 330 340 350
TINPHKKFVG QVYVLKKEEG GRHTPFFDGY RPQFYFRTTD VTGSIKLPEG
360 370 380 390
MEMVMPGDHI DMEVELITEI AMDEGLRFAI REGGRTVGSG VVTSIIE
Length:397
Mass (Da):43,557
Last modified:September 5, 2006 - v1
Checksum:i8C21DF00AC399AB6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000312 Genomic DNA Translation: ABG86236.1
CP000312 Genomic DNA Translation: ABG86432.1
RefSeqiWP_003452162.1, NC_008262.1

Genome annotation databases

EnsemblBacteriaiABG86236; ABG86236; CPR_2416
ABG86432; ABG86432; CPR_2402
GeneIDi29570175
KEGGicpr:CPR_2402
cpr:CPR_2416

Similar proteinsi

Entry informationi

Entry nameiEFTU_CLOPS
AccessioniPrimary (citable) accession number: Q0SQC8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: September 5, 2006
Last modified: May 23, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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