Q0SPE9 (URK_BORAP) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 43.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Uridine kinase EC=2.7.1.48 Alternative name(s): Cytidine monophosphokinase Uridine monophosphokinase | ||||
| Gene names |
| ||||
| Organism | Borrelia afzelii (strain PKo) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 390236 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group |
Protein attributes
| Sequence length | 207 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | ATP + uridine = ADP + UMP. HAMAP MF_00551 ATP + cytidine = ADP + CMP. HAMAP MF_00551 |
| Pathway | Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3. HAMAP MF_00551 Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1. HAMAP MF_00551 |
| Subcellular location | Cytoplasm By similarity HAMAP MF_00551. |
| Sequence similarities | Belongs to the uridine kinase family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphotransferase activity, alcohol group as acceptorInferred from electronic annotation. Source: InterPro uridine kinase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 207 | 207 | Uridine kinase HAMAP MF_00551 | PRO_1000017868 | |||||
Regions | |||||||||
| Nucleotide binding | 9 – 16 | 8 | ATP Potential | ||||||
Sequences
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References
| [1] | "Comparative genome analysis: selection pressure on the Borrelia vls cassettes is essential for infectivity." Gloeckner G., Schulte-Spechtel U., Schilhabel M., Felder M., Suehnel J., Wilske B., Platzer M. BMC Genomics 7:211-211(2006) [PubMed: 16914037] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PKo. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000395 Genomic DNA. Translation: ABH01279.1. |
| RefSeq | YP_709455.1. NC_008277.1. |
3D structure databases | |
| ProteinModelPortal | Q0SPE9. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q0SPE9. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBBORT00000003757; EBBORP00000003375; EBBORG00000003757. |
| GeneID | 4227180. |
| GenomeReviews | Gene locus BAPKO_0014 in contig CP000395_GR. |
| KEGG | baf:BAPKO_0014. |
| NMPDR | fig|390236.5.peg.82. |
| PATRIC | 37188329. VBIBorAfz3878_0083. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0572. |
| GeneTree | EBGT00050000007051. |
| HOGENOM | HBG527126. |
| OMA | NQFVEPT. |
| ProtClustDB | PRK05480. |
Enzyme and pathway databases | |
| BioCyc | BAFZ390236:BAPKO_0014-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00551. Uridine_kinase. [Tree] |
| InterPro | IPR006083. PRK/URK. IPR000764. Uridine_kinase. [Graphical view] |
| KO | K00876. |
| Pfam | PF00485. PRK. 1 hit. [Graphical view] |
| PRINTS | PR00988. URIDINKINASE. |
| TIGRFAMs | TIGR00235. Udk. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | URK_BORAP | ||||||||
| Accession | Primary (citable) accession number: Q0SPE9 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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