Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q0SPA9

- PGK_BORAP

UniProt

Q0SPA9 - PGK_BORAP

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Borrelia afzelii (strain PKo)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei37 – 371SubstrateUniRule annotation
Binding sitei119 – 1191SubstrateUniRule annotation
Binding sitei152 – 1521SubstrateUniRule annotation
Binding sitei202 – 2021ATPUniRule annotation
Binding sitei293 – 2931ATP; via carbonyl oxygenUniRule annotation
Binding sitei324 – 3241ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi350 – 3534ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:BAPKO_0056, BafPKo_0055
OrganismiBorrelia afzelii (strain PKo)
Taxonomic identifieri390236 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeBorreliaBorrelia burgdorferi group
ProteomesiUP000001825: Chromosome, UP000005216: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 393393Phosphoglycerate kinasePRO_1000192803Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi390236.BAPKO_0056.

Structurei

3D structure databases

ProteinModelPortaliQ0SPA9.
SMRiQ0SPA9. Positions 1-393.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni22 – 243Substrate bindingUniRule annotation
Regioni60 – 634Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiAGHPVGK.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0SPA9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSIKTVKDFN SFAGKRVLVR CDFNVPLKEG SISDDTRIKA ALPTIEYLKE
60 70 80 90 100
RGARIVLVSH LGRPEGKKNL KYSLKPVANR LSGLLNQDVK MFSDCIGSEI
110 120 130 140 150
VNNTLQMKDG DVVLLENVRF YAEEEKNDKN FAKKLSENGD VFVSDAFGAA
160 170 180 190 200
HRAHASTVGV SDYLPSVGGF LMEKEDKFLG EVLKNPEKPF VSIIGGSKVS
210 220 230 240 250
SKIAVLESLL SKSNVVVIGG GMAYTFLYSK GYSIGKSLLE SEYIDTASSF
260 270 280 290 300
LRKAKELGVK VILPLDHIVA DDFNKNSTPE YIDSLNIPEN KIGMDIGVNT
310 320 330 340 350
LKEIEKVVKT AKTIIWNGPL GVFEFDSFSK GTAKVAEMVA SCSGLTVVGG
360 370 380 390
GDSVAAVNKF NLSDKITHVS TGGGASLEYL EGKILPGIKV LEK
Length:393
Mass (Da):42,545
Last modified:September 5, 2006 - v1
Checksum:i4F89DC04A79E8CE6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000395 Genomic DNA. Translation: ABH01319.1.
CP002933 Genomic DNA. Translation: AEL69288.1.
RefSeqiWP_011600803.1. NC_017238.1.
YP_005592278.1. NC_017238.1.
YP_709495.1. NC_008277.1.

Genome annotation databases

EnsemblBacteriaiABH01319; ABH01319; BAPKO_0056.
AEL69288; AEL69288; BafPKo_0055.
GeneIDi12159010.
4227599.
KEGGibaf:BAPKO_0056.
bafz:BafPKo_0055.
PATRICi37188409. VBIBorAfz3878_0122.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000395 Genomic DNA. Translation: ABH01319.1 .
CP002933 Genomic DNA. Translation: AEL69288.1 .
RefSeqi WP_011600803.1. NC_017238.1.
YP_005592278.1. NC_017238.1.
YP_709495.1. NC_008277.1.

3D structure databases

ProteinModelPortali Q0SPA9.
SMRi Q0SPA9. Positions 1-393.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 390236.BAPKO_0056.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABH01319 ; ABH01319 ; BAPKO_0056 .
AEL69288 ; AEL69288 ; BafPKo_0055 .
GeneIDi 12159010.
4227599.
KEGGi baf:BAPKO_0056.
bafz:BafPKo_0055.
PATRICi 37188409. VBIBorAfz3878_0122.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227108.
KOi K00927.
OMAi AGHPVGK.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative genome analysis: selection pressure on the Borrelia vls cassettes is essential for infectivity."
    Gloeckner G., Schulte-Spechtel U., Schilhabel M., Felder M., Suehnel J., Wilske B., Platzer M.
    BMC Genomics 7:211-211(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PKo.
  2. "Whole-genome sequences of two Borrelia afzelii and two Borrelia garinii Lyme disease agent isolates."
    Casjens S.R., Mongodin E.F., Qiu W.G., Dunn J.J., Luft B.J., Fraser-Liggett C.M., Schutzer S.E.
    J. Bacteriol. 193:6995-6996(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PKo.

Entry informationi

Entry nameiPGK_BORAP
AccessioniPrimary (citable) accession number: Q0SPA9
Secondary accession number(s): G0IQQ2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 5, 2006
Last modified: October 29, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3