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Q0SPA9

- PGK_BORAP

UniProt

Q0SPA9 - PGK_BORAP

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Protein

Phosphoglycerate kinase

Gene
pgk, BAPKO_0056, BafPKo_0055
Organism
Borrelia afzelii (strain PKo)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei37 – 371Substrate By similarity
Binding sitei119 – 1191Substrate By similarity
Binding sitei152 – 1521Substrate By similarity
Binding sitei202 – 2021ATP By similarity
Binding sitei293 – 2931ATP; via carbonyl oxygen By similarity
Binding sitei324 – 3241ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi350 – 3534ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:BAPKO_0056, BafPKo_0055
OrganismiBorrelia afzelii (strain PKo)
Taxonomic identifieri390236 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeBorreliaBorrelia burgdorferi group
ProteomesiUP000001825: Chromosome, UP000005216: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 393393Phosphoglycerate kinaseUniRule annotationPRO_1000192803Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi390236.BAPKO_0056.

Structurei

3D structure databases

ProteinModelPortaliQ0SPA9.
SMRiQ0SPA9. Positions 1-393.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni22 – 243Substrate binding By similarity
Regioni60 – 634Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiAGHPVGK.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q0SPA9-1 [UniParc]FASTAAdd to Basket

« Hide

MSIKTVKDFN SFAGKRVLVR CDFNVPLKEG SISDDTRIKA ALPTIEYLKE    50
RGARIVLVSH LGRPEGKKNL KYSLKPVANR LSGLLNQDVK MFSDCIGSEI 100
VNNTLQMKDG DVVLLENVRF YAEEEKNDKN FAKKLSENGD VFVSDAFGAA 150
HRAHASTVGV SDYLPSVGGF LMEKEDKFLG EVLKNPEKPF VSIIGGSKVS 200
SKIAVLESLL SKSNVVVIGG GMAYTFLYSK GYSIGKSLLE SEYIDTASSF 250
LRKAKELGVK VILPLDHIVA DDFNKNSTPE YIDSLNIPEN KIGMDIGVNT 300
LKEIEKVVKT AKTIIWNGPL GVFEFDSFSK GTAKVAEMVA SCSGLTVVGG 350
GDSVAAVNKF NLSDKITHVS TGGGASLEYL EGKILPGIKV LEK 393
Length:393
Mass (Da):42,545
Last modified:September 5, 2006 - v1
Checksum:i4F89DC04A79E8CE6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000395 Genomic DNA. Translation: ABH01319.1.
CP002933 Genomic DNA. Translation: AEL69288.1.
RefSeqiYP_005592278.1. NC_017238.1.
YP_709495.1. NC_008277.1.

Genome annotation databases

EnsemblBacteriaiABH01319; ABH01319; BAPKO_0056.
AEL69288; AEL69288; BafPKo_0055.
GeneIDi12159010.
4227599.
KEGGibaf:BAPKO_0056.
bafz:BafPKo_0055.
PATRICi37188409. VBIBorAfz3878_0122.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000395 Genomic DNA. Translation: ABH01319.1 .
CP002933 Genomic DNA. Translation: AEL69288.1 .
RefSeqi YP_005592278.1. NC_017238.1.
YP_709495.1. NC_008277.1.

3D structure databases

ProteinModelPortali Q0SPA9.
SMRi Q0SPA9. Positions 1-393.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 390236.BAPKO_0056.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABH01319 ; ABH01319 ; BAPKO_0056 .
AEL69288 ; AEL69288 ; BafPKo_0055 .
GeneIDi 12159010.
4227599.
KEGGi baf:BAPKO_0056.
bafz:BafPKo_0055.
PATRICi 37188409. VBIBorAfz3878_0122.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227108.
KOi K00927.
OMAi AGHPVGK.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative genome analysis: selection pressure on the Borrelia vls cassettes is essential for infectivity."
    Gloeckner G., Schulte-Spechtel U., Schilhabel M., Felder M., Suehnel J., Wilske B., Platzer M.
    BMC Genomics 7:211-211(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PKo.
  2. "Whole-genome sequences of two Borrelia afzelii and two Borrelia garinii Lyme disease agent isolates."
    Casjens S.R., Mongodin E.F., Qiu W.G., Dunn J.J., Luft B.J., Fraser-Liggett C.M., Schutzer S.E.
    J. Bacteriol. 193:6995-6996(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PKo.

Entry informationi

Entry nameiPGK_BORAP
AccessioniPrimary (citable) accession number: Q0SPA9
Secondary accession number(s): G0IQQ2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: September 5, 2006
Last modified: June 11, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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